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7H51

Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with Z1198183601 (A71EV2A-x1180)

Functional Information from GO Data
ChainGOidnamespacecontents
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0016032biological_processviral process
B0006508biological_processproteolysis
B0008233molecular_functionpeptidase activity
B0016032biological_processviral process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsACT_SITE: For protease 2A activity => ECO:0000250|UniProtKB:P03300
ChainResidueDetails
AHIS21
AASP39
ACYS110
BHIS21
BASP39
BCYS110

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q9QF31
ChainResidueDetails
ACYS56
ACYS58
ACYS116
AHIS118
BCYS56
BCYS58
BCYS116
BHIS118

site_idSWS_FT_FI3
Number of Residues2
DetailsSITE: Cleavage; by protease 3C => ECO:0000250|UniProtKB:P03301
ChainResidueDetails
AGLN150
BGLN150

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PDB entries from 2024-10-30

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