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7H2Y

Group deposition for crystallographic fragment screening of Coxsackievirus A16 (G-10) 2A protease -- Crystal structure of Coxsackievirus A16 (G-10) 2A protease in complex with Z425757818 (A71EV2A-x0228)

Functional Information from GO Data
ChainGOidnamespacecontents
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0016032biological_processviral process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsACT_SITE: For protease 2A activity => ECO:0000250|UniProtKB:P03300
ChainResidueDetails
AHIS21
AASP39
ACYS110

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q9QF31
ChainResidueDetails
ACYS56
ACYS58
ACYS116
AHIS118

site_idSWS_FT_FI3
Number of Residues1
DetailsSITE: Cleavage; by protease 3C => ECO:0000250|UniProtKB:P03301
ChainResidueDetails
AGLN150

226707

PDB entries from 2024-10-30

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