7FF0

Pseudomonas aeruginosa Virulence Factor Regulator with cAMP ligand and auranofin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000976	molecular_function	transcription cis-regulatory region binding
A	0001216	molecular_function	DNA-binding transcription activator activity
A	0001217	molecular_function	DNA-binding transcription repressor activity
A	0003677	molecular_function	DNA binding
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0005829	cellular_component	cytosol
A	0006351	biological_process	DNA-templated transcription
A	0006355	biological_process	regulation of DNA-templated transcription
A	0030552	molecular_function	cAMP binding
A	0032993	cellular_component	protein-DNA complex
A	0043565	molecular_function	sequence-specific DNA binding
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
B	0000976	molecular_function	transcription cis-regulatory region binding
B	0001216	molecular_function	DNA-binding transcription activator activity
B	0001217	molecular_function	DNA-binding transcription repressor activity
B	0003677	molecular_function	DNA binding
B	0003700	molecular_function	DNA-binding transcription factor activity
B	0005829	cellular_component	cytosol
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0030552	molecular_function	cAMP binding
B	0032993	cellular_component	protein-DNA complex
B	0043565	molecular_function	sequence-specific DNA binding
B	0045892	biological_process	negative regulation of DNA-templated transcription
B	0045893	biological_process	positive regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00042
Number of Residues	24
Details	HTH_CRP_1 Crp-type HTH domain signature. ITRqeIGrIVGcSreMv.GRvLksL

Chain	Residue	Details
A	ILE172-LEU195

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site_id	PS00888
Number of Residues	17
Details	CNMP_BINDING_1 Cyclic nucleotide-binding domain signature 1. IIyAGDrCEtLFFIikG

Chain	Residue	Details
A	ILE31-GLY47

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site_id	PS00889
Number of Residues	22
Details	CNMP_BINDING_2 Cyclic nucleotide-binding domain signature 2. FGElGLfekegseqe..RSAwVrA

Chain	Residue	Details
A	PHE72-ALA93

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	38
Details	DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00387

Chain	Residue	Details
A	ARG174-LYS193
B	ARG174-LYS193

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:21665969, ECO:0007744|PDB:2OZ6

Chain	Residue	Details
A	ARG59
A	ARG87
A	THR132
A	ARG179
A	ARG185
B	ARG59
B	GLY73
B	ARG87
B	THR132
B	ARG179
B	ARG185
A	GLY73

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