7F94

Structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel with two conformationally different hemichannels

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005922	cellular_component	connexin complex
A	0007154	biological_process	cell communication
B	0005922	cellular_component	connexin complex
B	0007154	biological_process	cell communication
C	0005922	cellular_component	connexin complex
C	0007154	biological_process	cell communication
D	0005922	cellular_component	connexin complex
D	0007154	biological_process	cell communication
E	0005922	cellular_component	connexin complex
E	0007154	biological_process	cell communication
F	0005922	cellular_component	connexin complex
F	0007154	biological_process	cell communication
G	0005922	cellular_component	connexin complex
G	0007154	biological_process	cell communication
H	0005922	cellular_component	connexin complex
H	0007154	biological_process	cell communication
I	0005922	cellular_component	connexin complex
I	0007154	biological_process	cell communication
J	0005922	cellular_component	connexin complex
J	0007154	biological_process	cell communication
K	0005922	cellular_component	connexin complex
K	0007154	biological_process	cell communication
L	0005922	cellular_component	connexin complex
L	0007154	biological_process	cell communication

Functional Information from PROSITE/UniProt

site_id	PS00407
Number of Residues	14
Details	CONNEXINS_1 Connexins signature 1. CNTqQPGCenVCYD

Chain	Residue	Details
A	CYS54-ASP67

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site_id	PS00408
Number of Residues	17
Details	CONNEXINS_2 Connexins signature 2. Ckrd.PCphqVDCFLSRP

Chain	Residue	Details
A	CYS187-PRO203

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	252
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"UniProtKB","id":"P08050","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	960
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	732
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"UniProtKB","id":"P08050","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	12
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P08050","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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