Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008239 | molecular_function | dipeptidyl-peptidase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0050784 | biological_process | cocaine catabolic process |
| A | 0052689 | molecular_function | carboxylic ester hydrolase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 95 |
| Details | Region: {"description":"2"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 113 |
| Details | Region: {"description":"1B"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 219 |
| Details | Region: {"description":"3"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"PubMed","id":"11742345","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"11742345","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Probably involved in activating the substrate carbonyl and the acyl enzyme for hydrolysis"} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 6 |
| Details | M-CSA 465 |
| Chain | Residue | Details |
| A | TYR44 | transition state stabiliser |
| A | ALA117 | covalent catalysis, proton shuttle (general acid/base) |
| A | TYR118 | electrostatic stabiliser |
| A | TRP166 | activator |
| A | ASP259 | activator, electrostatic stabiliser |
| A | HIS287 | proton shuttle (general acid/base) |
