7F20

L-lactate oxidase with L-lactate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016491	molecular_function	oxidoreductase activity
B	0016491	molecular_function	oxidoreductase activity

Functional Information from PROSITE/UniProt

site_id	PS00557
Number of Residues	7
Details	FMN_HYDROXY_ACID_DH_1 FMN-dependent alpha-hydroxy acid dehydrogenases active site. SNHGARQ

Chain	Residue	Details
A	SER-105-GLN-99
A	SER263-GLN269

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:27302031

Chain	Residue	Details
A	PRO-87
B	PRO-87

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:17517371, ECO:0000269|PubMed:25423902, ECO:0007744|PDB:2E77, ECO:0007744|PDB:4RJE

Chain	Residue	Details
A	TYR-312
B	ALA-137
B	PRO-87
B	ALA-84
A	TYR-206
A	PRO-171
A	ALA-137
A	PRO-87
A	ALA-84
B	TYR-312
B	TYR-206
B	PRO-171

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:17517371, ECO:0000269|PubMed:18367206, ECO:0007744|PDB:2DU2, ECO:0007744|PDB:2E77, ECO:0007744|PDB:2NLI

Chain	Residue	Details
A	PRO-259
A	GLY-56
A	SER-32
B	PRO-259
B	GLY-56
B	SER-32

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site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:17517371, ECO:0000269|PubMed:18367206, ECO:0007744|PDB:2E77, ECO:0007744|PDB:2NLI

Chain	Residue	Details
A	SER-230
A	THR-180
A	ALA-111
A	THR-89
B	SER-230
B	THR-180
B	ALA-111
B	THR-89

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site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:17517371, ECO:0007744|PDB:2E77

Chain	Residue	Details
A	GLN-208
B	GLN-208

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site_id	SWS_FT_FI6
Number of Residues	2
Details	SITE: Is suggested to participate in control of opening/closing motions of the active-site lid in A.viridans LOX => ECO:0000305|PubMed:27302031

Chain	Residue	Details
A	ALA-137
B	ALA-137

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