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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

7EWL

cryo-EM structure of apo GPR158

Functional Information from GO Data
ChainGOidnamespacecontents
A0004930molecular_functionG protein-coupled receptor activity
A0007186biological_processG protein-coupled receptor signaling pathway
A0016020cellular_componentmembrane
B0004930molecular_functionG protein-coupled receptor activity
B0007186biological_processG protein-coupled receptor signaling pathway
B0016020cellular_componentmembrane
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues42
DetailsTransmembrane: {"description":"Helical; Name=1","evidences":[{"source":"PubMed","id":"34793198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34815401","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues48
DetailsTopological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"34793198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34815401","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues44
DetailsTransmembrane: {"description":"Helical; Name=2","evidences":[{"source":"PubMed","id":"34793198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34815401","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues6
DetailsTopological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"34793198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34815401","evidenceCode":"ECO:0000269"},{"evidenceCode":"ECO:0000305"},{"source":"PDB","id":"7EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues44
DetailsTransmembrane: {"description":"Helical; Name=3","evidences":[{"source":"PubMed","id":"34793198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34815401","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues42
DetailsTransmembrane: {"description":"Helical; Name=4","evidences":[{"source":"PubMed","id":"34793198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34815401","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues72
DetailsTopological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"34793198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34815401","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues40
DetailsTransmembrane: {"description":"Helical; Name=5","evidences":[{"source":"PubMed","id":"34793198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34815401","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues42
DetailsTransmembrane: {"description":"Helical; Name=6","evidences":[{"source":"PubMed","id":"34793198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34815401","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues42
DetailsTransmembrane: {"description":"Helical; Name=7","evidences":[{"source":"PubMed","id":"34793198","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34815401","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7EWL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7EWR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7SHF","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues8
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"36996198","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues10
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246905

PDB entries from 2025-12-31

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