7EVV
Co-crystal Structure of Toxoplasma gondii Prolyl tRNA Synthetase (TgPRS) in complex with JE6 and L-pro
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004827 | molecular_function | proline-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006433 | biological_process | prolyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue JE6 A 901 |
| Chain | Residue |
| A | ARG470 |
| A | ALA557 |
| A | THR558 |
| A | GLY590 |
| A | THR592 |
| A | ARG594 |
| A | PRO902 |
| A | HOH1103 |
| A | HOH1120 |
| A | GLU472 |
| A | LYS474 |
| A | PHE479 |
| A | LEU480 |
| A | ARG481 |
| A | THR482 |
| A | PHE485 |
| A | GLN555 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue PRO A 902 |
| Chain | Residue |
| A | THR439 |
| A | GLU441 |
| A | ARG470 |
| A | TRP487 |
| A | GLU489 |
| A | PHE534 |
| A | THR558 |
| A | HIS560 |
| A | SER588 |
| A | TRP589 |
| A | GLY590 |
| A | JE6901 |
| A | HOH1036 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue CL A 903 |
| Chain | Residue |
| A | GLN379 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue MPD A 904 |
| Chain | Residue |
| A | ILE356 |
| A | TYR365 |
| A | MET367 |
| A | PHE479 |
| A | THR482 |
| A | GLU484 |
| A | THR593 |
| A | HOH1196 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue MPD A 905 |
| Chain | Residue |
| A | GLU497 |
