7EIP
Crystal structure of ligand-free chondroitin ABC lyase I
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0006027 | biological_process | glycosaminoglycan catabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030246 | molecular_function | carbohydrate binding |
| A | 0034000 | molecular_function | chondroitin-sulfate-ABC endolyase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000269|PubMed:15691229, ECO:0000269|PubMed:16108757 |
| Chain | Residue | Details |
| A | HIS501 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor => ECO:0000255 |
| Chain | Residue | Details |
| A | TYR508 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12706721, ECO:0007744|PDB:1HN0 |
| Chain | Residue | Details |
| A | HIS43 | |
| A | MET70 | |
| A | GLN73 | |
| A | ASP211 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Transition state stabilizer => ECO:0000255 |
| Chain | Residue | Details |
| A | ARG560 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Important for catalytic activity |
| Chain | Residue | Details |
| A | GLU653 |
