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7EGE

TFIID in canonical conformation

Functional Information from GO Data
ChainGOidnamespacecontents
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0000209biological_processprotein polyubiquitination
A0000785cellular_componentchromatin
A0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
A0001091molecular_functionRNA polymerase II general transcription initiation factor binding
A0001181molecular_functionRNA polymerase I general transcription initiation factor activity
A0002039molecular_functionp53 binding
A0003677molecular_functionDNA binding
A0004402molecular_functionhistone acetyltransferase activity
A0004672molecular_functionprotein kinase activity
A0004674molecular_functionprotein serine/threonine kinase activity
A0004676molecular_function3-phosphoinositide-dependent protein kinase activity
A0004677molecular_functionDNA-dependent protein kinase activity
A0004679molecular_functionAMP-activated protein kinase activity
A0004694molecular_functioneukaryotic translation initiation factor 2alpha kinase activity
A0004711molecular_functionribosomal protein S6 kinase activity
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005667cellular_componenttranscription regulator complex
A0005669cellular_componenttranscription factor TFIID complex
A0005730cellular_componentnucleolus
A0006325biological_processchromatin organization
A0006338biological_processchromatin remodeling
A0006352biological_processDNA-templated transcription initiation
A0006361biological_processtranscription initiation at RNA polymerase I promoter
A0006366biological_processtranscription by RNA polymerase II
A0006367biological_processtranscription initiation at RNA polymerase II promoter
A0006468biological_processprotein phosphorylation
A0006511biological_processubiquitin-dependent protein catabolic process
A0006974biological_processDNA damage response
A0010629biological_processnegative regulation of gene expression
A0016251molecular_functionRNA polymerase II general transcription initiation factor activity
A0016301molecular_functionkinase activity
A0016746molecular_functionacyltransferase activity
A0016922molecular_functionnuclear receptor binding
A0017025molecular_functionTBP-class protein binding
A0018105biological_processpeptidyl-serine phosphorylation
A0018107biological_processpeptidyl-threonine phosphorylation
A0030901biological_processmidbrain development
A0032092biological_processpositive regulation of protein binding
A0032436biological_processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
A0032931molecular_functionhistone H3K56 acetyltransferase activity
A0034644biological_processcellular response to UV
A0035175molecular_functionhistone H3S10 kinase activity
A0035402molecular_functionhistone H3T11 kinase activity
A0035403molecular_functionhistone H3T6 kinase activity
A0035979molecular_functionhistone H2AXS139 kinase activity
A0036408molecular_functionhistone H3K14 acetyltransferase activity
A0042789biological_processmRNA transcription by RNA polymerase II
A0043565molecular_functionsequence-specific DNA binding
A0043992molecular_functionhistone H3K9 acetyltransferase activity
A0043993molecular_functionhistone H3K18 acetyltransferase activity
A0043994molecular_functionhistone H3K23 acetyltransferase activity
A0043995molecular_functionhistone H4K5 acetyltransferase activity
A0043996molecular_functionhistone H4K8 acetyltransferase activity
A0043997molecular_functionhistone H4K12 acetyltransferase activity
A0043999molecular_functionhistone H2AK5 acetyltransferase activity
A0044012molecular_functionhistone H2AK9 acetyltransferase activity
A0044014molecular_functionhistone H2BK5 acetyltransferase activity
A0044015molecular_functionhistone H2BK12 acetyltransferase activity
A0044016molecular_functionhistone H3K4 acetyltransferase activity
A0044017molecular_functionhistone H3K27 acetyltransferase activity
A0044018molecular_functionhistone H3K36 acetyltransferase activity
A0044022molecular_functionhistone H3S28 kinase activity
A0044023molecular_functionhistone H4S1 kinase activity
A0044024molecular_functionhistone H2AS1 kinase activity
A0044025molecular_functionhistone H2BS14 kinase activity
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0046777biological_processprotein autophosphorylation
A0046972molecular_functionhistone H4K16 acetyltransferase activity
A0046982molecular_functionprotein heterodimerization activity
A0050821biological_processprotein stabilization
A0051123biological_processRNA polymerase II preinitiation complex assembly
A0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
A0061628molecular_functionH3K27me3 modified histone binding
A0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
A0061631molecular_functionubiquitin conjugating enzyme activity
A0061733molecular_functionpeptide-lysine-N-acetyltransferase activity
A0070577molecular_functionlysine-acetylated histone binding
A0071318biological_processcellular response to ATP
A0071339cellular_componentMLL1 complex
A0072354molecular_functionhistone H3T3 kinase activity
A0072371molecular_functionhistone H2AS121 kinase activity
A0072518molecular_functionRho-dependent protein serine/threonine kinase activity
A0106310molecular_functionprotein serine kinase activity
A0140416molecular_functiontranscription regulator inhibitor activity
A0140566molecular_functionhistone reader activity
A0140823molecular_functionhistone H2BS36 kinase activity
A0140855molecular_functionhistone H3S57 kinase activity
A0140857molecular_functionhistone H3T45 kinase activity
A0140908molecular_functionhistone H3K122 acetyltransferase activity
A1901796biological_processregulation of signal transduction by p53 class mediator
A1902806biological_processregulation of cell cycle G1/S phase transition
A1905502molecular_functionacetyl-CoA binding
A1905524biological_processnegative regulation of protein autoubiquitination
A1990244molecular_functionhistone H2AT120 kinase activity
A2000059biological_processnegative regulation of ubiquitin-dependent protein catabolic process
A2000825biological_processpositive regulation of androgen receptor activity
B0000086biological_processG2/M transition of mitotic cell cycle
B0000976molecular_functiontranscription cis-regulatory region binding
B0003682molecular_functionchromatin binding
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005669cellular_componenttranscription factor TFIID complex
B0006282biological_processregulation of DNA repair
B0006357biological_processregulation of transcription by RNA polymerase II
B0006367biological_processtranscription initiation at RNA polymerase II promoter
B0014070biological_processresponse to organic cyclic compound
B0016251molecular_functionRNA polymerase II general transcription initiation factor activity
B0033276cellular_componenttranscription factor TFTC complex
B0042789biological_processmRNA transcription by RNA polymerase II
B0045893biological_processpositive regulation of DNA-templated transcription
B0051123biological_processRNA polymerase II preinitiation complex assembly
B0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
D0000785cellular_componentchromatin
D0001046molecular_functioncore promoter sequence-specific DNA binding
D0001541biological_processovarian follicle development
D0001673cellular_componentmale germ cell nucleus
D0003677molecular_functionDNA binding
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005667cellular_componenttranscription regulator complex
D0005669cellular_componenttranscription factor TFIID complex
D0005829cellular_componentcytosol
D0006282biological_processregulation of DNA repair
D0006351biological_processDNA-templated transcription
D0006352biological_processDNA-templated transcription initiation
D0006357biological_processregulation of transcription by RNA polymerase II
D0006366biological_processtranscription by RNA polymerase II
D0006367biological_processtranscription initiation at RNA polymerase II promoter
D0016251molecular_functionRNA polymerase II general transcription initiation factor activity
D0017162molecular_functionaryl hydrocarbon receptor binding
D0032991cellular_componentprotein-containing complex
D0033276cellular_componenttranscription factor TFTC complex
D0042789biological_processmRNA transcription by RNA polymerase II
D0045893biological_processpositive regulation of DNA-templated transcription
D0046982molecular_functionprotein heterodimerization activity
D0051123biological_processRNA polymerase II preinitiation complex assembly
D0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
D0071339cellular_componentMLL1 complex
E0000124cellular_componentSAGA complex
E0000785cellular_componentchromatin
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005669cellular_componenttranscription factor TFIID complex
E0005730cellular_componentnucleolus
E0006282biological_processregulation of DNA repair
E0006352biological_processDNA-templated transcription initiation
E0006357biological_processregulation of transcription by RNA polymerase II
E0006367biological_processtranscription initiation at RNA polymerase II promoter
E0015629cellular_componentactin cytoskeleton
E0016251molecular_functionRNA polymerase II general transcription initiation factor activity
E0033276cellular_componenttranscription factor TFTC complex
E0042789biological_processmRNA transcription by RNA polymerase II
E0042802molecular_functionidentical protein binding
E0045893biological_processpositive regulation of DNA-templated transcription
E0051123biological_processRNA polymerase II preinitiation complex assembly
E0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
F0000124cellular_componentSAGA complex
F0003677molecular_functionDNA binding
F0003713molecular_functiontranscription coactivator activity
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005669cellular_componenttranscription factor TFIID complex
F0005829cellular_componentcytosol
F0006282biological_processregulation of DNA repair
F0006352biological_processDNA-templated transcription initiation
F0006357biological_processregulation of transcription by RNA polymerase II
F0006366biological_processtranscription by RNA polymerase II
F0006367biological_processtranscription initiation at RNA polymerase II promoter
F0006915biological_processapoptotic process
F0016251molecular_functionRNA polymerase II general transcription initiation factor activity
F0017162molecular_functionaryl hydrocarbon receptor binding
F0032991cellular_componentprotein-containing complex
F0033276cellular_componenttranscription factor TFTC complex
F0042789biological_processmRNA transcription by RNA polymerase II
F0045786biological_processnegative regulation of cell cycle
F0045893biological_processpositive regulation of DNA-templated transcription
F0046695cellular_componentSLIK (SAGA-like) complex
F0046982molecular_functionprotein heterodimerization activity
F0051123biological_processRNA polymerase II preinitiation complex assembly
F0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
F0071339cellular_componentMLL1 complex
G0000122biological_processnegative regulation of transcription by RNA polymerase II
G0000296biological_processspermine transport
G0000976molecular_functiontranscription cis-regulatory region binding
G0001097molecular_functionTFIIH-class transcription factor complex binding
G0001673cellular_componentmale germ cell nucleus
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005654cellular_componentnucleoplasm
G0005667cellular_componenttranscription regulator complex
G0005669cellular_componenttranscription factor TFIID complex
G0005737cellular_componentcytoplasm
G0006282biological_processregulation of DNA repair
G0006352biological_processDNA-templated transcription initiation
G0006357biological_processregulation of transcription by RNA polymerase II
G0006366biological_processtranscription by RNA polymerase II
G0006367biological_processtranscription initiation at RNA polymerase II promoter
G0006469biological_processnegative regulation of protein kinase activity
G0016251molecular_functionRNA polymerase II general transcription initiation factor activity
G0030520biological_processestrogen receptor signaling pathway
G0033276cellular_componenttranscription factor TFTC complex
G0035035molecular_functionhistone acetyltransferase binding
G0042789biological_processmRNA transcription by RNA polymerase II
G0042809molecular_functionnuclear vitamin D receptor binding
G0045344biological_processnegative regulation of MHC class I biosynthetic process
G0045347biological_processnegative regulation of MHC class II biosynthetic process
G0045892biological_processnegative regulation of DNA-templated transcription
G0045893biological_processpositive regulation of DNA-templated transcription
G0045944biological_processpositive regulation of transcription by RNA polymerase II
G0046966molecular_functionnuclear thyroid hormone receptor binding
G0046982molecular_functionprotein heterodimerization activity
G0051123biological_processRNA polymerase II preinitiation complex assembly
G0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
G0061628molecular_functionH3K27me3 modified histone binding
G0071339cellular_componentMLL1 complex
G0106140molecular_functionP-TEFb complex binding
G0140297molecular_functionDNA-binding transcription factor binding
H0001112biological_processDNA-templated transcription open complex formation
H0001833biological_processinner cell mass cell proliferation
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005669cellular_componenttranscription factor TFIID complex
H0005737cellular_componentcytoplasm
H0006367biological_processtranscription initiation at RNA polymerase II promoter
H0016251molecular_functionRNA polymerase II general transcription initiation factor activity
H0030154biological_processcell differentiation
H0042789biological_processmRNA transcription by RNA polymerase II
H0045598biological_processregulation of fat cell differentiation
H0046982molecular_functionprotein heterodimerization activity
H0048471cellular_componentperinuclear region of cytoplasm
H0051123biological_processRNA polymerase II preinitiation complex assembly
H0051457biological_processmaintenance of protein location in nucleus
H0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
I0000124cellular_componentSAGA complex
I0000492biological_processbox C/D snoRNP assembly
I0000976molecular_functiontranscription cis-regulatory region binding
I0002039molecular_functionp53 binding
I0003677molecular_functionDNA binding
I0003713molecular_functiontranscription coactivator activity
I0004402molecular_functionhistone acetyltransferase activity
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005669cellular_componenttranscription factor TFIID complex
I0006282biological_processregulation of DNA repair
I0006338biological_processchromatin remodeling
I0006352biological_processDNA-templated transcription initiation
I0006355biological_processregulation of DNA-templated transcription
I0006357biological_processregulation of transcription by RNA polymerase II
I0006974biological_processDNA damage response
I0016251molecular_functionRNA polymerase II general transcription initiation factor activity
I0032435biological_processnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
I0033276cellular_componenttranscription factor TFTC complex
I0042789biological_processmRNA transcription by RNA polymerase II
I0043066biological_processnegative regulation of apoptotic process
I0043484biological_processregulation of RNA splicing
I0045893biological_processpositive regulation of DNA-templated transcription
I0045944biological_processpositive regulation of transcription by RNA polymerase II
I0046982molecular_functionprotein heterodimerization activity
I0050821biological_processprotein stabilization
I0051117molecular_functionATPase binding
I0051123biological_processRNA polymerase II preinitiation complex assembly
I0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
I0060760biological_processpositive regulation of response to cytokine stimulus
I0070555biological_processresponse to interleukin-1
I0070742molecular_functionC2H2 zinc finger domain binding
I0070761cellular_componentpre-snoRNP complex
I0071339cellular_componentMLL1 complex
I0140297molecular_functionDNA-binding transcription factor binding
I1902065biological_processresponse to L-glutamate
I1902166biological_processnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
J0000082biological_processG1/S transition of mitotic cell cycle
J0000124cellular_componentSAGA complex
J0001673cellular_componentmale germ cell nucleus
J0001701biological_processin utero embryonic development
J0001756biological_processsomitogenesis
J0001889biological_processliver development
J0001892biological_processembryonic placenta development
J0003677molecular_functionDNA binding
J0004402molecular_functionhistone acetyltransferase activity
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0005654cellular_componentnucleoplasm
J0005669cellular_componenttranscription factor TFIID complex
J0005737cellular_componentcytoplasm
J0006282biological_processregulation of DNA repair
J0006338biological_processchromatin remodeling
J0006352biological_processDNA-templated transcription initiation
J0006355biological_processregulation of DNA-templated transcription
J0006357biological_processregulation of transcription by RNA polymerase II
J0006366biological_processtranscription by RNA polymerase II
J0006367biological_processtranscription initiation at RNA polymerase II promoter
J0006915biological_processapoptotic process
J0010467biological_processgene expression
J0010468biological_processregulation of gene expression
J0016251molecular_functionRNA polymerase II general transcription initiation factor activity
J0019899molecular_functionenzyme binding
J0030331molecular_functionnuclear estrogen receptor binding
J0033276cellular_componenttranscription factor TFTC complex
J0035264biological_processmulticellular organism growth
J0036285biological_processSAGA complex assembly
J0042789biological_processmRNA transcription by RNA polymerase II
J0042802molecular_functionidentical protein binding
J0043484biological_processregulation of RNA splicing
J0045893biological_processpositive regulation of DNA-templated transcription
J0048371biological_processlateral mesodermal cell differentiation
J0048471cellular_componentperinuclear region of cytoplasm
J0051123biological_processRNA polymerase II preinitiation complex assembly
J0060173biological_processlimb development
J0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
J0065003biological_processprotein-containing complex assembly
J0070063molecular_functionRNA polymerase binding
J0070365biological_processhepatocyte differentiation
J0097550cellular_componenttranscription preinitiation complex
J1905069biological_processallantois development
J1990841molecular_functionpromoter-specific chromatin binding
L0000124cellular_componentSAGA complex
L0003677molecular_functionDNA binding
L0003713molecular_functiontranscription coactivator activity
L0005515molecular_functionprotein binding
L0005634cellular_componentnucleus
L0005654cellular_componentnucleoplasm
L0005669cellular_componenttranscription factor TFIID complex
L0006282biological_processregulation of DNA repair
L0006352biological_processDNA-templated transcription initiation
L0006355biological_processregulation of DNA-templated transcription
L0006357biological_processregulation of transcription by RNA polymerase II
L0006366biological_processtranscription by RNA polymerase II
L0006367biological_processtranscription initiation at RNA polymerase II promoter
L0016251molecular_functionRNA polymerase II general transcription initiation factor activity
L0017025molecular_functionTBP-class protein binding
L0033276cellular_componenttranscription factor TFTC complex
L0042789biological_processmRNA transcription by RNA polymerase II
L0043484biological_processregulation of RNA splicing
L0045893biological_processpositive regulation of DNA-templated transcription
L0045944biological_processpositive regulation of transcription by RNA polymerase II
L0046982molecular_functionprotein heterodimerization activity
L0051123biological_processRNA polymerase II preinitiation complex assembly
L0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
L0140297molecular_functionDNA-binding transcription factor binding
P0000785cellular_componentchromatin
P0000791cellular_componenteuchromatin
P0000976molecular_functiontranscription cis-regulatory region binding
P0000978molecular_functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
P0000979molecular_functionRNA polymerase II core promoter sequence-specific DNA binding
P0000995molecular_functionRNA polymerase III general transcription initiation factor activity
P0001046molecular_functioncore promoter sequence-specific DNA binding
P0001091molecular_functionRNA polymerase II general transcription initiation factor binding
P0001093molecular_functionTFIIB-class transcription factor binding
P0001164molecular_functionRNA polymerase I core promoter sequence-specific DNA binding
P0001188biological_processRNA polymerase I preinitiation complex assembly
P0001673cellular_componentmale germ cell nucleus
P0001674cellular_componentfemale germ cell nucleus
P0001939cellular_componentfemale pronucleus
P0001940cellular_componentmale pronucleus
P0003677molecular_functionDNA binding
P0005515molecular_functionprotein binding
P0005634cellular_componentnucleus
P0005654cellular_componentnucleoplasm
P0005668cellular_componentRNA polymerase transcription factor SL1 complex
P0005669cellular_componenttranscription factor TFIID complex
P0005672cellular_componenttranscription factor TFIIA complex
P0005737cellular_componentcytoplasm
P0006352biological_processDNA-templated transcription initiation
P0006366biological_processtranscription by RNA polymerase II
P0006367biological_processtranscription initiation at RNA polymerase II promoter
P0006383biological_processtranscription by RNA polymerase III
P0007283biological_processspermatogenesis
P0016251molecular_functionRNA polymerase II general transcription initiation factor activity
P0017162molecular_functionaryl hydrocarbon receptor binding
P0019899molecular_functionenzyme binding
P0032991cellular_componentprotein-containing complex
P0042789biological_processmRNA transcription by RNA polymerase II
P0045120cellular_componentpronucleus
P0045893biological_processpositive regulation of DNA-templated transcription
P0051123biological_processRNA polymerase II preinitiation complex assembly
P0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
P0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
P0140297molecular_functionDNA-binding transcription factor binding
c0000122biological_processnegative regulation of transcription by RNA polymerase II
c0001673cellular_componentmale germ cell nucleus
c0002039molecular_functionp53 binding
c0005515molecular_functionprotein binding
c0005634cellular_componentnucleus
c0005654cellular_componentnucleoplasm
c0005669cellular_componenttranscription factor TFIID complex
c0016251molecular_functionRNA polymerase II general transcription initiation factor activity
c0031965cellular_componentnuclear membrane
c0042789biological_processmRNA transcription by RNA polymerase II
c0043433biological_processnegative regulation of DNA-binding transcription factor activity
c0045944biological_processpositive regulation of transcription by RNA polymerase II
c0046872molecular_functionmetal ion binding
c0046982molecular_functionprotein heterodimerization activity
c0051123biological_processRNA polymerase II preinitiation complex assembly
c0051457biological_processmaintenance of protein location in nucleus
c0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
c0140416molecular_functiontranscription regulator inhibitor activity
d0000785cellular_componentchromatin
d0001046molecular_functioncore promoter sequence-specific DNA binding
d0001541biological_processovarian follicle development
d0001673cellular_componentmale germ cell nucleus
d0003677molecular_functionDNA binding
d0005515molecular_functionprotein binding
d0005634cellular_componentnucleus
d0005654cellular_componentnucleoplasm
d0005667cellular_componenttranscription regulator complex
d0005669cellular_componenttranscription factor TFIID complex
d0005829cellular_componentcytosol
d0006282biological_processregulation of DNA repair
d0006351biological_processDNA-templated transcription
d0006352biological_processDNA-templated transcription initiation
d0006357biological_processregulation of transcription by RNA polymerase II
d0006366biological_processtranscription by RNA polymerase II
d0006367biological_processtranscription initiation at RNA polymerase II promoter
d0016251molecular_functionRNA polymerase II general transcription initiation factor activity
d0017162molecular_functionaryl hydrocarbon receptor binding
d0032991cellular_componentprotein-containing complex
d0033276cellular_componenttranscription factor TFTC complex
d0042789biological_processmRNA transcription by RNA polymerase II
d0045893biological_processpositive regulation of DNA-templated transcription
d0046982molecular_functionprotein heterodimerization activity
d0051123biological_processRNA polymerase II preinitiation complex assembly
d0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
d0071339cellular_componentMLL1 complex
e0000124cellular_componentSAGA complex
e0000785cellular_componentchromatin
e0005515molecular_functionprotein binding
e0005634cellular_componentnucleus
e0005654cellular_componentnucleoplasm
e0005669cellular_componenttranscription factor TFIID complex
e0005730cellular_componentnucleolus
e0006282biological_processregulation of DNA repair
e0006352biological_processDNA-templated transcription initiation
e0006357biological_processregulation of transcription by RNA polymerase II
e0006367biological_processtranscription initiation at RNA polymerase II promoter
e0015629cellular_componentactin cytoskeleton
e0016251molecular_functionRNA polymerase II general transcription initiation factor activity
e0033276cellular_componenttranscription factor TFTC complex
e0042789biological_processmRNA transcription by RNA polymerase II
e0042802molecular_functionidentical protein binding
e0045893biological_processpositive regulation of DNA-templated transcription
e0051123biological_processRNA polymerase II preinitiation complex assembly
e0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
f0000124cellular_componentSAGA complex
f0003677molecular_functionDNA binding
f0003713molecular_functiontranscription coactivator activity
f0005515molecular_functionprotein binding
f0005634cellular_componentnucleus
f0005654cellular_componentnucleoplasm
f0005669cellular_componenttranscription factor TFIID complex
f0005829cellular_componentcytosol
f0006282biological_processregulation of DNA repair
f0006352biological_processDNA-templated transcription initiation
f0006357biological_processregulation of transcription by RNA polymerase II
f0006366biological_processtranscription by RNA polymerase II
f0006367biological_processtranscription initiation at RNA polymerase II promoter
f0006915biological_processapoptotic process
f0016251molecular_functionRNA polymerase II general transcription initiation factor activity
f0017162molecular_functionaryl hydrocarbon receptor binding
f0032991cellular_componentprotein-containing complex
f0033276cellular_componenttranscription factor TFTC complex
f0042789biological_processmRNA transcription by RNA polymerase II
f0045786biological_processnegative regulation of cell cycle
f0045893biological_processpositive regulation of DNA-templated transcription
f0046695cellular_componentSLIK (SAGA-like) complex
f0046982molecular_functionprotein heterodimerization activity
f0051123biological_processRNA polymerase II preinitiation complex assembly
f0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
f0071339cellular_componentMLL1 complex
i0000124cellular_componentSAGA complex
i0000492biological_processbox C/D snoRNP assembly
i0000976molecular_functiontranscription cis-regulatory region binding
i0002039molecular_functionp53 binding
i0003677molecular_functionDNA binding
i0003713molecular_functiontranscription coactivator activity
i0004402molecular_functionhistone acetyltransferase activity
i0005515molecular_functionprotein binding
i0005634cellular_componentnucleus
i0005654cellular_componentnucleoplasm
i0005669cellular_componenttranscription factor TFIID complex
i0006282biological_processregulation of DNA repair
i0006338biological_processchromatin remodeling
i0006352biological_processDNA-templated transcription initiation
i0006355biological_processregulation of DNA-templated transcription
i0006357biological_processregulation of transcription by RNA polymerase II
i0006974biological_processDNA damage response
i0016251molecular_functionRNA polymerase II general transcription initiation factor activity
i0032435biological_processnegative regulation of proteasomal ubiquitin-dependent protein catabolic process
i0033276cellular_componenttranscription factor TFTC complex
i0042789biological_processmRNA transcription by RNA polymerase II
i0043066biological_processnegative regulation of apoptotic process
i0043484biological_processregulation of RNA splicing
i0045893biological_processpositive regulation of DNA-templated transcription
i0045944biological_processpositive regulation of transcription by RNA polymerase II
i0046982molecular_functionprotein heterodimerization activity
i0050821biological_processprotein stabilization
i0051117molecular_functionATPase binding
i0051123biological_processRNA polymerase II preinitiation complex assembly
i0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
i0060760biological_processpositive regulation of response to cytokine stimulus
i0070555biological_processresponse to interleukin-1
i0070742molecular_functionC2H2 zinc finger domain binding
i0070761cellular_componentpre-snoRNP complex
i0071339cellular_componentMLL1 complex
i0140297molecular_functionDNA-binding transcription factor binding
i1902065biological_processresponse to L-glutamate
i1902166biological_processnegative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
j0000082biological_processG1/S transition of mitotic cell cycle
j0000124cellular_componentSAGA complex
j0001673cellular_componentmale germ cell nucleus
j0001701biological_processin utero embryonic development
j0001756biological_processsomitogenesis
j0001889biological_processliver development
j0001892biological_processembryonic placenta development
j0003677molecular_functionDNA binding
j0004402molecular_functionhistone acetyltransferase activity
j0005515molecular_functionprotein binding
j0005634cellular_componentnucleus
j0005654cellular_componentnucleoplasm
j0005669cellular_componenttranscription factor TFIID complex
j0005737cellular_componentcytoplasm
j0006282biological_processregulation of DNA repair
j0006338biological_processchromatin remodeling
j0006352biological_processDNA-templated transcription initiation
j0006355biological_processregulation of DNA-templated transcription
j0006357biological_processregulation of transcription by RNA polymerase II
j0006366biological_processtranscription by RNA polymerase II
j0006367biological_processtranscription initiation at RNA polymerase II promoter
j0006915biological_processapoptotic process
j0010467biological_processgene expression
j0010468biological_processregulation of gene expression
j0016251molecular_functionRNA polymerase II general transcription initiation factor activity
j0019899molecular_functionenzyme binding
j0030331molecular_functionnuclear estrogen receptor binding
j0033276cellular_componenttranscription factor TFTC complex
j0035264biological_processmulticellular organism growth
j0036285biological_processSAGA complex assembly
j0042789biological_processmRNA transcription by RNA polymerase II
j0042802molecular_functionidentical protein binding
j0043484biological_processregulation of RNA splicing
j0045893biological_processpositive regulation of DNA-templated transcription
j0048371biological_processlateral mesodermal cell differentiation
j0048471cellular_componentperinuclear region of cytoplasm
j0051123biological_processRNA polymerase II preinitiation complex assembly
j0060173biological_processlimb development
j0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
j0065003biological_processprotein-containing complex assembly
j0070063molecular_functionRNA polymerase binding
j0070365biological_processhepatocyte differentiation
j0097550cellular_componenttranscription preinitiation complex
j1905069biological_processallantois development
j1990841molecular_functionpromoter-specific chromatin binding
k0003677molecular_functionDNA binding
k0003713molecular_functiontranscription coactivator activity
k0005515molecular_functionprotein binding
k0005634cellular_componentnucleus
k0005654cellular_componentnucleoplasm
k0005669cellular_componenttranscription factor TFIID complex
k0005794cellular_componentGolgi apparatus
k0006366biological_processtranscription by RNA polymerase II
k0006367biological_processtranscription initiation at RNA polymerase II promoter
k0016251molecular_functionRNA polymerase II general transcription initiation factor activity
k0017025molecular_functionTBP-class protein binding
k0042789biological_processmRNA transcription by RNA polymerase II
k0042809molecular_functionnuclear vitamin D receptor binding
k0043923biological_processpositive regulation by host of viral transcription
k0046966molecular_functionnuclear thyroid hormone receptor binding
k0046982molecular_functionprotein heterodimerization activity
k0051123biological_processRNA polymerase II preinitiation complex assembly
k0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
l0000124cellular_componentSAGA complex
l0003677molecular_functionDNA binding
l0003713molecular_functiontranscription coactivator activity
l0005515molecular_functionprotein binding
l0005634cellular_componentnucleus
l0005654cellular_componentnucleoplasm
l0005669cellular_componenttranscription factor TFIID complex
l0006282biological_processregulation of DNA repair
l0006352biological_processDNA-templated transcription initiation
l0006355biological_processregulation of DNA-templated transcription
l0006357biological_processregulation of transcription by RNA polymerase II
l0006366biological_processtranscription by RNA polymerase II
l0006367biological_processtranscription initiation at RNA polymerase II promoter
l0016251molecular_functionRNA polymerase II general transcription initiation factor activity
l0017025molecular_functionTBP-class protein binding
l0033276cellular_componenttranscription factor TFTC complex
l0042789biological_processmRNA transcription by RNA polymerase II
l0043484biological_processregulation of RNA splicing
l0045893biological_processpositive regulation of DNA-templated transcription
l0045944biological_processpositive regulation of transcription by RNA polymerase II
l0046982molecular_functionprotein heterodimerization activity
l0051123biological_processRNA polymerase II preinitiation complex assembly
l0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
l0140297molecular_functionDNA-binding transcription factor binding
m0003677molecular_functionDNA binding
m0005515molecular_functionprotein binding
m0005634cellular_componentnucleus
m0005654cellular_componentnucleoplasm
m0005669cellular_componenttranscription factor TFIID complex
m0005730cellular_componentnucleolus
m0006352biological_processDNA-templated transcription initiation
m0006366biological_processtranscription by RNA polymerase II
m0006367biological_processtranscription initiation at RNA polymerase II promoter
m0016251molecular_functionRNA polymerase II general transcription initiation factor activity
m0017025molecular_functionTBP-class protein binding
m0042789biological_processmRNA transcription by RNA polymerase II
m0046982molecular_functionprotein heterodimerization activity
m0051123biological_processRNA polymerase II preinitiation complex assembly
m0060261biological_processpositive regulation of transcription initiation by RNA polymerase II
Functional Information from PROSITE/UniProt
site_idPS00351
Number of Residues50
DetailsTFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePRttaLIFsSGKMvctGAKseeqsrlAarkyarvV
ChainResidueDetails
PTYR192-VAL241
PTYR283-LEU332

site_idPS00633
Number of Residues58
DetailsBROMODOMAIN_1 Bromodomain signature. TypFhtpvNakvvk..DYYkiItrpMdlqtLrenvrkrl..Ypsreefrehlel.IvkNSatY
ChainResidueDetails
ATHR1402-TYR1459
ASER1525-TYR1582

site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. VATGsaDrTVRLWDV
ChainResidueDetails
EVAL642-VAL656
ELEU684-ILE698
ELEU726-ALA740

site_idPS01359
Number of Residues45
DetailsZF_PHD_1 Zinc finger PHD-type signature. CpgCnkpddgspm....................................IgCdd..Cddw.YHwpCvgimtappeemq.................................WfCpkC
ChainResidueDetails
cCYS868-CYS912

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N-acetylserine => ECO:0007744|PubMed:19413330
ChainResidueDetails
JSER2
jSER2
PLYS218
PASN257
PARG294

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
JSER44
jSER44
dARG424
dARG435
cHIS891
cCYS894
cCYS909
cCYS912

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569
ChainResidueDetails
JTHR48
dLYS595
dLYS597
dLYS605
dLYS611
dLYS621
dLYS631
dLYS658
jTHR48
DLYS597
DLYS605
DLYS611
DLYS621
DLYS631
DLYS658
dLYS594

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: N6,N6,N6-trimethyllysine; alternate => ECO:0000269|PubMed:15099517, ECO:0000269|PubMed:16415881, ECO:0000269|PubMed:25959397
ChainResidueDetails
JLYS189
jLYS189
iSER152
iSER196

site_idSWS_FT_FI5
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8VI33
ChainResidueDetails
ISER155
iSER155
ASER1799
ASER1802
AILE1820

site_idSWS_FT_FI6
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332
ChainResidueDetails
ISER158
iSER158

site_idSWS_FT_FI7
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332
ChainResidueDetails
ITHR159
iTHR159
fSER634
fSER636

site_idSWS_FT_FI8
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648
ChainResidueDetails
ITHR161
iTHR161

site_idSWS_FT_FI9
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q8VI33
ChainResidueDetails
ITHR164
iTHR164

site_idSWS_FT_FI10
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
ITHR178
iTHR178
fLYS196

site_idSWS_FT_FI11
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648
ChainResidueDetails
ISER181
iSER181

227561

PDB entries from 2024-11-20

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