Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7EG3

Crystal structure of the apoAequorin complex with (S)-HM-daCTZ

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0008218	biological_process	bioluminescence
A	0046872	molecular_function	metal ion binding
B	0005509	molecular_function	calcium ion binding
B	0008218	biological_process	bioluminescence
B	0046872	molecular_function	metal ion binding
C	0005509	molecular_function	calcium ion binding
C	0008218	biological_process	bioluminescence
C	0046872	molecular_function	metal ion binding
D	0005509	molecular_function	calcium ion binding
D	0008218	biological_process	bioluminescence
D	0046872	molecular_function	metal ion binding
E	0005509	molecular_function	calcium ion binding
E	0008218	biological_process	bioluminescence
E	0046872	molecular_function	metal ion binding
F	0005509	molecular_function	calcium ion binding
F	0008218	biological_process	bioluminescence
F	0046872	molecular_function	metal ion binding
G	0005509	molecular_function	calcium ion binding
G	0008218	biological_process	bioluminescence
G	0046872	molecular_function	metal ion binding
H	0005509	molecular_function	calcium ion binding
H	0008218	biological_process	bioluminescence
H	0046872	molecular_function	metal ion binding
I	0005509	molecular_function	calcium ion binding
I	0008218	biological_process	bioluminescence
I	0046872	molecular_function	metal ion binding
J	0005509	molecular_function	calcium ion binding
J	0008218	biological_process	bioluminescence
J	0046872	molecular_function	metal ion binding
K	0005509	molecular_function	calcium ion binding
K	0008218	biological_process	bioluminescence
K	0046872	molecular_function	metal ion binding
L	0005509	molecular_function	calcium ion binding
L	0008218	biological_process	bioluminescence
L	0046872	molecular_function	metal ion binding
M	0005509	molecular_function	calcium ion binding
M	0008218	biological_process	bioluminescence
M	0046872	molecular_function	metal ion binding
N	0005509	molecular_function	calcium ion binding
N	0008218	biological_process	bioluminescence
N	0046872	molecular_function	metal ion binding
O	0005509	molecular_function	calcium ion binding
O	0008218	biological_process	bioluminescence
O	0046872	molecular_function	metal ion binding
P	0005509	molecular_function	calcium ion binding
P	0008218	biological_process	bioluminescence
P	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue J2U A 201

Chain	Residue
A	HIS16
A	LEU112
A	TYR132
A	MET165
A	HIS169
A	TRP173
A	TYR184
A	HOH302
A	MET19
A	ALA40
A	PHE66
A	TYR82
A	TRP86
A	ILE105
A	TRP108
A	GLY109

site_id	AC2
Number of Residues	17
Details	binding site for residue J2U B 201

Chain	Residue
B	HIS16
B	MET19
B	LEU23
B	LYS39
B	ALA40
B	TYR82
B	TRP86
B	ILE105
B	TRP108
B	GLY109
B	LEU112
B	PHE113
B	TYR132
B	HIS169
B	TRP173
B	TYR184
B	HOH303

site_id	AC3
Number of Residues	19
Details	binding site for residue J2U C 201

Chain	Residue
C	HIS16
C	MET19
C	LEU23
C	LYS39
C	ALA40
C	PHE66
C	TYR82
C	TRP86
C	ILE105
C	TRP108
C	GLY109
C	LEU112
C	PHE113
C	TYR132
C	MET165
C	HIS169
C	TRP173
C	TYR184
C	HOH309

site_id	AC4
Number of Residues	18
Details	binding site for residue J2U D 201

Chain	Residue
D	HIS16
D	MET19
D	LYS39
D	ALA40
D	TYR82
D	TRP86
D	ILE105
D	TRP108
D	GLY109
D	LEU112
D	PHE113
D	TYR132
D	ILE138
D	MET165
D	HIS169
D	TRP173
D	TYR184
D	HOH316

site_id	AC5
Number of Residues	17
Details	binding site for residue J2U E 201

Chain	Residue
E	HIS16
E	MET19
E	LEU23
E	LYS39
E	ALA40
E	TYR82
E	TRP86
E	ILE105
E	GLY109
E	LEU112
E	PHE113
E	TYR132
E	MET165
E	HIS169
E	TRP173
E	TYR184
E	HOH315

site_id	AC6
Number of Residues	17
Details	binding site for residue J2U F 201

Chain	Residue
F	MET165
F	HIS169
F	TRP173
F	TYR184
F	HOH320
F	HIS16
F	MET19
F	LYS39
F	ALA40
F	TYR82
F	TRP86
F	ILE105
F	TRP108
F	GLY109
F	LEU112
F	PHE113
F	TYR132

site_id	AC7
Number of Residues	19
Details	binding site for residue J2U G 201

Chain	Residue
G	HIS16
G	MET19
G	LEU23
G	LYS39
G	ALA40
G	PHE66
G	TYR82
G	TRP86
G	ILE105
G	TRP108
G	GLY109
G	LEU112
G	PHE113
G	TYR132
G	MET165
G	HIS169
G	TRP173
G	TYR184
G	HOH325

site_id	AC8
Number of Residues	17
Details	binding site for residue J2U H 201

Chain	Residue
H	HIS16
H	MET19
H	LEU23
H	LYS39
H	ALA40
H	TYR82
H	TRP86
H	ILE105
H	TRP108
H	GLY109
H	LEU112
H	PHE113
H	TYR132
H	HIS169
H	TRP173
H	TYR184
H	HOH305

site_id	AC9
Number of Residues	17
Details	binding site for residue J2U I 201

Chain	Residue
I	HIS16
I	MET19
I	LYS39
I	ALA40
I	TYR82
I	TRP86
I	ILE105
I	TRP108
I	GLY109
I	LEU112
I	PHE113
I	TYR132
I	MET165
I	HIS169
I	TRP173
I	TYR184
I	HOH337

site_id	AD1
Number of Residues	17
Details	binding site for residue J2U J 201

Chain	Residue
J	HIS16
J	MET19
J	LYS39
J	ALA40
J	TYR82
J	TRP86
J	ILE105
J	TRP108
J	GLY109
J	LEU112
J	PHE113
J	TYR132
J	MET165
J	HIS169
J	TRP173
J	TYR184
J	HOH318

site_id	AD2
Number of Residues	19
Details	binding site for residue J2U K 201

Chain	Residue
K	HIS16
K	MET19
K	LEU23
K	LYS39
K	ALA40
K	TYR82
K	TRP86
K	ILE105
K	TRP108
K	GLY109
K	LEU112
K	PHE113
K	TYR132
K	ILE138
K	MET165
K	HIS169
K	TRP173
K	TYR184
K	HOH304

site_id	AD3
Number of Residues	18
Details	binding site for residue J2U L 201

Chain	Residue
L	HIS16
L	MET19
L	LEU23
L	LYS39
L	ALA40
L	TYR82
L	TRP86
L	ILE105
L	TRP108
L	GLY109
L	LEU112
L	PHE113
L	TYR132
L	MET165
L	HIS169
L	TRP173
L	TYR184
L	HOH317

site_id	AD4
Number of Residues	18
Details	binding site for residue J2U M 201

Chain	Residue
M	HIS16
M	MET19
M	LEU23
M	LYS39
M	ALA40
M	TYR82
M	TRP86
M	ILE105
M	TRP108
M	GLY109
M	LEU112
M	PHE113
M	TYR132
M	MET165
M	HIS169
M	TRP173
M	TYR184
M	HOH305

site_id	AD5
Number of Residues	17
Details	binding site for residue J2U N 201

Chain	Residue
N	HIS16
N	MET19
N	LYS39
N	ALA40
N	TYR82
N	TRP86
N	ILE105
N	TRP108
N	GLY109
N	LEU112
N	PHE113
N	TYR132
N	MET165
N	HIS169
N	TRP173
N	TYR184
N	HOH321

site_id	AD6
Number of Residues	17
Details	binding site for residue J2U O 201

Chain	Residue
O	HIS16
O	MET19
O	LEU23
O	LYS39
O	TYR82
O	TRP86
O	ILE105
O	TRP108
O	GLY109
O	LEU112
O	PHE113
O	TYR132
O	MET165
O	HIS169
O	TRP173
O	TYR184
O	HOH327

site_id	AD7
Number of Residues	18
Details	binding site for residue J2U P 201

Chain	Residue
P	HIS16
P	MET19
P	LEU23
P	LYS39
P	ALA40
P	TYR82
P	TRP86
P	ILE105
P	TRP108
P	GLY109
P	LEU112
P	PHE113
P	TYR132
P	MET165
P	HIS169
P	TRP173
P	TYR184
P	HOH318

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DVNHNGKISldEM

Chain	Residue	Details
A	ASP24-MET36
A	ASP117-TRP129
A	ASP153-MET165

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	560
Details	Domain: {"description":"EF-hand 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	864
Details	Domain: {"description":"EF-hand 2","evidences":[{"source":"PubMed","id":"10830969","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	464
Details	Domain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	560
Details	Domain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	480
Details	Region: {"description":"May interact with the chromophore"}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	224
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	16
Details	Site: {"description":"Required for bioluminescence"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)