7EER

Crystal structure of Tryptophanyl-tRNA synthetase from Bacillus stearothermophilus in complex with 05E6 and ATP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004830	molecular_function	tryptophan-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006436	biological_process	tryptophanyl-tRNA aminoacylation
B	0000166	molecular_function	nucleotide binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004830	molecular_function	tryptophan-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006412	biological_process	translation
B	0006418	biological_process	tRNA aminoacylation for protein translation
B	0006436	biological_process	tryptophanyl-tRNA aminoacylation
C	0000166	molecular_function	nucleotide binding
C	0004812	molecular_function	aminoacyl-tRNA ligase activity
C	0004830	molecular_function	tryptophan-tRNA ligase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006412	biological_process	translation
C	0006418	biological_process	tRNA aminoacylation for protein translation
C	0006436	biological_process	tryptophanyl-tRNA aminoacylation
D	0000166	molecular_function	nucleotide binding
D	0004812	molecular_function	aminoacyl-tRNA ligase activity
D	0004830	molecular_function	tryptophan-tRNA ligase activity
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0006412	biological_process	translation
D	0006418	biological_process	tRNA aminoacylation for protein translation
D	0006436	biological_process	tryptophanyl-tRNA aminoacylation

Functional Information from PROSITE/UniProt

site_id	PS00178
Number of Residues	10
Details	AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. P..SGvITIGNY

Chain	Residue	Details
A	PRO10-TYR19

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00140, ECO:0000269|PubMed:26555258, ECO:0007744|PDB:5DK4

Chain	Residue	Details
A	GLN9
B	GLY144
B	ILE183
B	LYS192
C	GLN9
C	GLY17
C	ASP132
C	GLY144
C	ILE183
C	LYS192
D	GLN9
A	GLY17
D	GLY17
D	ASP132
D	GLY144
D	ILE183
D	LYS192
A	ASP132
A	GLY144
A	ILE183
A	LYS192
B	GLN9
B	GLY17
B	ASP132

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	3
Details	M-CSA 481

Chain	Residue	Details
A	LYS111	electrostatic stabiliser
A	LYS192	electrostatic stabiliser
A	LYS195	electrostatic stabiliser

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site_id	MCSA2
Number of Residues	3
Details	M-CSA 481

Chain	Residue	Details
B	LYS111	electrostatic stabiliser
B	LYS192	electrostatic stabiliser
B	LYS195	electrostatic stabiliser

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site_id	MCSA3
Number of Residues	3
Details	M-CSA 481

Chain	Residue	Details
C	LYS111	electrostatic stabiliser
C	LYS192	electrostatic stabiliser
C	LYS195	electrostatic stabiliser

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site_id	MCSA4
Number of Residues	3
Details	M-CSA 481

Chain	Residue	Details
D	LYS111	electrostatic stabiliser
D	LYS192	electrostatic stabiliser
D	LYS195	electrostatic stabiliser

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