7EAO
The structure of the A20-binding inhibitor of NF-kB 1 in complex with tri-ubiquitin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0002755 | biological_process | MyD88-dependent toll-like receptor signaling pathway |
| B | 0043124 | biological_process | negative regulation of I-kappaB kinase/NF-kappaB signaling |
| B | 0050727 | biological_process | regulation of inflammatory response |
| B | 0070373 | biological_process | negative regulation of ERK1 and ERK2 cascade |
| C | 0002755 | biological_process | MyD88-dependent toll-like receptor signaling pathway |
| C | 0043124 | biological_process | negative regulation of I-kappaB kinase/NF-kappaB signaling |
| C | 0050727 | biological_process | regulation of inflammatory response |
| C | 0070373 | biological_process | negative regulation of ERK1 and ERK2 cascade |
Functional Information from PROSITE/UniProt
| site_id | PS00299 |
| Number of Residues | 26 |
| Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
| Chain | Residue | Details |
| A | LYS27-ASP52 | |
| A | LYS127-ASP152 | |
| A | LYS227-ASP252 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 75 |
| Details | Domain: {"description":"Ubiquitin-like 7","evidences":[{"source":"PROSITE-ProRule","id":"PRU00214","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 75 |
| Details | Domain: {"description":"Ubiquitin-like 8","evidences":[{"source":"PROSITE-ProRule","id":"PRU00214","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 116 |
| Details | Region: {"description":"Ubiquitin-binding domain (UBD)"} |
| Chain | Residue | Details |
