7E9S
Archaeal oligosaccharyltransferase AglB from Archaeoglobus fulgidus in complex with an inhibitory peptide and a dolichol-phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004576 | molecular_function | oligosaccharyl transferase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006486 | biological_process | protein glycosylation |
| A | 0016020 | cellular_component | membrane |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 62 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:24127570 |
| Chain | Residue | Details |
| A | MET1-VAL16 | |
| A | PHE132-ASP133 | |
| A | LYS185-ALA199 | |
| A | VAL239-ALA241 | |
| A | GLY304-GLY312 | |
| A | TYR397-SER404 | |
| A | TYR453-TYR468 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 271 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:24127570 |
| Chain | Residue | Details |
| A | LEU17-VAL36 | |
| A | LEU374-ALA396 | |
| A | PHE405-GLY423 | |
| A | ALA428-LEU452 | |
| A | PHE469-SER494 | |
| A | GLY102-VAL131 | |
| A | LYS134-GLN153 | |
| A | HIS163-TRP184 | |
| A | TYR200-VAL212 | |
| A | GLY216-PHE238 | |
| A | ASP242-LEU262 | |
| A | GLN280-VAL303 | |
| A | ARG313-LEU330 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 508 |
| Details | TOPO_DOM: Extracellular => ECO:0000305|PubMed:24127570 |
| Chain | Residue | Details |
| A | PHE37-SER101 | |
| A | ARG154-HIS162 | |
| A | LEU213-TRP215 | |
| A | PRO263-PHE279 | |
| A | PHE331-THR373 | |
| A | GLN424-PHE427 | |
| A | TYR495-LEU868 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:24127570, ECO:0000269|PubMed:27997792, ECO:0007744|PDB:3WAK |
| Chain | Residue | Details |
| A | ASP47 | |
| A | ASP161 | |
| A | HIS163 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:24127570 |
| Chain | Residue | Details |
| A | HIS81 | |
| A | HIS162 | |
| A | ARG426 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | SITE: Interacts with target acceptor peptide in protein substrate => ECO:0000269|PubMed:27997792 |
| Chain | Residue | Details |
| A | ASP47 | |
| A | GLU360 | |
| A | LYS618 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | SITE: Important for catalytic activity => ECO:0000250|UniProtKB:B9KDD4 |
| Chain | Residue | Details |
| A | ARG154 |
