7E8P

Crystal structure of a Flavin-dependent Monooxygenase HadA wild type complexed with reduced FAD and 4-nitrophenol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
B	0004497	molecular_function	monooxygenase activity
B	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
C	0004497	molecular_function	monooxygenase activity
C	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
D	0004497	molecular_function	monooxygenase activity
D	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors

Functional Information from PDB Data

site_id	AC1
Number of Residues	26
Details	binding site for residue FDA A 600

Chain	Residue
A	ARG101
A	ASP254
A	PHE443
A	PHE446
A	ASN447
A	THR449
A	HOH704
A	HOH713
A	HOH738
A	HOH753
A	HOH853
A	PRO152
B	ARG326
B	ASP383
B	LEU384
B	ARG387
B	HOH724
B	HOH743
B	HOH773
A	PHE154
A	VAL155
A	GLN158
A	ARG161
A	ILE191
A	GLY192
A	THR193

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site_id	AC2
Number of Residues	6
Details	binding site for residue NPO A 601

Chain	Residue
A	PHE206
A	ARG208
A	PHE286
A	HIS290
A	GLY448
A	THR449

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site_id	AC3
Number of Residues	22
Details	binding site for residue FDA B 600

Chain	Residue
A	ILE320
A	ARG326
A	ASP383
A	LEU384
A	GLY386
A	ARG387
A	HOH734
A	HOH790
A	HOH823
B	ARG101
B	PRO152
B	PHE154
B	VAL155
B	GLN158
B	ARG161
B	ILE191
B	THR193
B	PHE443
B	PHE446
B	ASN447
B	PRO450
B	HOH742

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site_id	AC4
Number of Residues	27
Details	binding site for residue FDA C 601

Chain	Residue
C	ARG101
C	PRO152
C	PHE154
C	VAL155
C	GLN158
C	ARG161
C	ILE191
C	THR193
C	PHE443
C	PHE446
C	ASN447
C	THR449
C	PRO450
C	HOH730
C	HOH742
C	HOH816
C	HOH818
C	HOH854
D	ILE320
D	ARG326
D	ASP383
D	LEU384
D	GLY386
D	ARG387
D	HOH723
D	HOH751
D	HOH771

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site_id	AC5
Number of Residues	4
Details	binding site for residue NPO C 602

Chain	Residue
C	PHE432
C	SER438
C	PHE441
D	NPO602

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site_id	AC6
Number of Residues	28
Details	binding site for residue FDA D 601

Chain	Residue
D	ARG161
D	ILE191
D	THR193
D	ARG208
D	ASP254
D	PHE443
D	PHE446
D	ASN447
D	HOH705
D	HOH736
D	HOH747
D	HOH762
D	HOH774
D	HOH789
C	ILE320
C	ARG326
C	ASP383
C	LEU384
C	GLY386
C	ARG387
C	HOH778
C	HOH797
C	HOH833
D	ARG101
D	PRO152
D	PHE154
D	VAL155
D	GLN158

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site_id	AC7
Number of Residues	6
Details	binding site for residue NPO D 602

Chain	Residue
C	ILE378
C	PHE432
C	NPO602
D	PHE432
D	SER438
D	PHE441

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