7E4X
Structure of Enolase from Mycobacterium tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000015 | cellular_component | phosphopyruvate hydratase complex |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004634 | molecular_function | phosphopyruvate hydratase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006096 | biological_process | glycolytic process |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0009986 | cellular_component | cell surface |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000015 | cellular_component | phosphopyruvate hydratase complex |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004634 | molecular_function | phosphopyruvate hydratase activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006096 | biological_process | glycolytic process |
| B | 0009274 | cellular_component | peptidoglycan-based cell wall |
| B | 0009986 | cellular_component | cell surface |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000015 | cellular_component | phosphopyruvate hydratase complex |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0004634 | molecular_function | phosphopyruvate hydratase activity |
| C | 0005576 | cellular_component | extracellular region |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0006096 | biological_process | glycolytic process |
| C | 0009274 | cellular_component | peptidoglycan-based cell wall |
| C | 0009986 | cellular_component | cell surface |
| C | 0016829 | molecular_function | lyase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000015 | cellular_component | phosphopyruvate hydratase complex |
| D | 0000287 | molecular_function | magnesium ion binding |
| D | 0004634 | molecular_function | phosphopyruvate hydratase activity |
| D | 0005576 | cellular_component | extracellular region |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0006096 | biological_process | glycolytic process |
| D | 0009274 | cellular_component | peptidoglycan-based cell wall |
| D | 0009986 | cellular_component | cell surface |
| D | 0016829 | molecular_function | lyase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0000015 | cellular_component | phosphopyruvate hydratase complex |
| E | 0000287 | molecular_function | magnesium ion binding |
| E | 0004634 | molecular_function | phosphopyruvate hydratase activity |
| E | 0005576 | cellular_component | extracellular region |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0006096 | biological_process | glycolytic process |
| E | 0009274 | cellular_component | peptidoglycan-based cell wall |
| E | 0009986 | cellular_component | cell surface |
| E | 0016829 | molecular_function | lyase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0000015 | cellular_component | phosphopyruvate hydratase complex |
| F | 0000287 | molecular_function | magnesium ion binding |
| F | 0004634 | molecular_function | phosphopyruvate hydratase activity |
| F | 0005576 | cellular_component | extracellular region |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0005886 | cellular_component | plasma membrane |
| F | 0006096 | biological_process | glycolytic process |
| F | 0009274 | cellular_component | peptidoglycan-based cell wall |
| F | 0009986 | cellular_component | cell surface |
| F | 0016829 | molecular_function | lyase activity |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0000015 | cellular_component | phosphopyruvate hydratase complex |
| G | 0000287 | molecular_function | magnesium ion binding |
| G | 0004634 | molecular_function | phosphopyruvate hydratase activity |
| G | 0005576 | cellular_component | extracellular region |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0005886 | cellular_component | plasma membrane |
| G | 0006096 | biological_process | glycolytic process |
| G | 0009274 | cellular_component | peptidoglycan-based cell wall |
| G | 0009986 | cellular_component | cell surface |
| G | 0016829 | molecular_function | lyase activity |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0000015 | cellular_component | phosphopyruvate hydratase complex |
| H | 0000287 | molecular_function | magnesium ion binding |
| H | 0004634 | molecular_function | phosphopyruvate hydratase activity |
| H | 0005576 | cellular_component | extracellular region |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0005886 | cellular_component | plasma membrane |
| H | 0006096 | biological_process | glycolytic process |
| H | 0009274 | cellular_component | peptidoglycan-based cell wall |
| H | 0009986 | cellular_component | cell surface |
| H | 0016829 | molecular_function | lyase activity |
| H | 0046872 | molecular_function | metal ion binding |
Functional Information from PROSITE/UniProt
| site_id | PS00164 |
| Number of Residues | 14 |
| Details | ENOLASE Enolase signature. LLVKvNQIGTLTET |
| Chain | Residue | Details |
| A | LEU332-THR345 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"37860976","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"37860976","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37860976","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7E4F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37860976","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CLL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"37860976","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6L7D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CLK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CLL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7DLR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7E4F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00318","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"37860976","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CKP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 32 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37860976","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7DLR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7E4F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37860976","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6L7D","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CLK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CLL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"37860976","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CLK","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 88 |
| Details | Modified residue: {"description":"Glutamate methyl ester (Glu)","evidences":[{"source":"PubMed","id":"37385399","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 56 |
| Details | Modified residue: {"description":"Aspartate methyl ester","evidences":[{"source":"PubMed","id":"37385399","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"37385399","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"37385399","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 16 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"37385399","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
