7E44

Crystal structure of NudC complexed with dpCoA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000210	molecular_function	NAD+ diphosphatase activity
A	0000287	molecular_function	magnesium ion binding
A	0006402	biological_process	mRNA catabolic process
A	0006734	biological_process	NADH metabolic process
A	0006742	biological_process	NADP catabolic process
A	0008270	molecular_function	zinc ion binding
A	0016787	molecular_function	hydrolase activity
A	0019677	biological_process	NAD catabolic process
A	0030145	molecular_function	manganese ion binding
A	0035529	molecular_function	NADH pyrophosphatase activity
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
A	0048255	biological_process	mRNA stabilization
A	0110153	molecular_function	RNA NAD-cap (NMN-forming) hydrolase activity
A	0110155	biological_process	NAD-cap decapping
B	0000210	molecular_function	NAD+ diphosphatase activity
B	0000287	molecular_function	magnesium ion binding
B	0006402	biological_process	mRNA catabolic process
B	0006734	biological_process	NADH metabolic process
B	0006742	biological_process	NADP catabolic process
B	0008270	molecular_function	zinc ion binding
B	0016787	molecular_function	hydrolase activity
B	0019677	biological_process	NAD catabolic process
B	0030145	molecular_function	manganese ion binding
B	0035529	molecular_function	NADH pyrophosphatase activity
B	0042803	molecular_function	protein homodimerization activity
B	0046872	molecular_function	metal ion binding
B	0048255	biological_process	mRNA stabilization
B	0110153	molecular_function	RNA NAD-cap (NMN-forming) hydrolase activity
B	0110155	biological_process	NAD-cap decapping
E	0000210	molecular_function	NAD+ diphosphatase activity
E	0000287	molecular_function	magnesium ion binding
E	0006402	biological_process	mRNA catabolic process
E	0006734	biological_process	NADH metabolic process
E	0006742	biological_process	NADP catabolic process
E	0008270	molecular_function	zinc ion binding
E	0016787	molecular_function	hydrolase activity
E	0019677	biological_process	NAD catabolic process
E	0030145	molecular_function	manganese ion binding
E	0035529	molecular_function	NADH pyrophosphatase activity
E	0042803	molecular_function	protein homodimerization activity
E	0046872	molecular_function	metal ion binding
E	0048255	biological_process	mRNA stabilization
E	0110153	molecular_function	RNA NAD-cap (NMN-forming) hydrolase activity
E	0110155	biological_process	NAD-cap decapping
F	0000210	molecular_function	NAD+ diphosphatase activity
F	0000287	molecular_function	magnesium ion binding
F	0006402	biological_process	mRNA catabolic process
F	0006734	biological_process	NADH metabolic process
F	0006742	biological_process	NADP catabolic process
F	0008270	molecular_function	zinc ion binding
F	0016787	molecular_function	hydrolase activity
F	0019677	biological_process	NAD catabolic process
F	0030145	molecular_function	manganese ion binding
F	0035529	molecular_function	NADH pyrophosphatase activity
F	0042803	molecular_function	protein homodimerization activity
F	0046872	molecular_function	metal ion binding
F	0048255	biological_process	mRNA stabilization
F	0110153	molecular_function	RNA NAD-cap (NMN-forming) hydrolase activity
F	0110155	biological_process	NAD-cap decapping

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:27428510, ECO:0007744|PDB:5IW4

Chain	Residue	Details
A	LYS25
B	LYS25
E	LYS25
F	LYS25

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:27428510, ECO:0007744|PDB:5IW5

Chain	Residue	Details
A	ARG69
B	ARG69
E	ARG69
F	ARG69

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:27428510, ECO:0000269|PubMed:27561816, ECO:0000269|Ref.8, ECO:0007744|PDB:1VK6, ECO:0007744|PDB:2GB5, ECO:0007744|PDB:5ISY, ECO:0007744|PDB:5IW4, ECO:0007744|PDB:5IW5

Chain	Residue	Details
A	CYS98
E	CYS101
E	CYS116
E	CYS119
F	CYS98
F	CYS101
F	CYS116
F	CYS119
A	CYS101
A	CYS116
A	CYS119
B	CYS98
B	CYS101
B	CYS116
B	CYS119
E	CYS98

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:27561816, ECO:0007744|PDB:5ISY

Chain	Residue	Details
A	GLU111
B	GLU111
E	GLU111
F	GLU111

---

site_id	SWS_FT_FI5
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:27428510, ECO:0000269|PubMed:27561816, ECO:0007744|PDB:5ISY, ECO:0007744|PDB:5IW4

Chain	Residue	Details
A	TYR124
F	TYR124
F	GLN192
F	ALA241
A	GLN192
A	ALA241
B	TYR124
B	GLN192
B	ALA241
E	TYR124
E	GLN192
E	ALA241

---

site_id	SWS_FT_FI6
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9DCN1

Chain	Residue	Details
A	ALA158
E	GLU174
E	GLN178
E	GLU219
F	ALA158
F	GLU174
F	GLN178
F	GLU219
A	GLU174
A	GLN178
A	GLU219
B	ALA158
B	GLU174
B	GLN178
B	GLU219
E	ALA158

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