7E27

Structure of PfFNT in complex with MMV007839

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0015513	molecular_function	high-affinity secondary active nitrite transmembrane transporter activity
A	0015650	molecular_function	lactate:proton symporter activity
A	0015706	biological_process	nitrate transmembrane transport
A	0015707	biological_process	nitrite transport
A	0016020	cellular_component	membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0035873	biological_process	lactate transmembrane transport
A	0055085	biological_process	transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0015513	molecular_function	high-affinity secondary active nitrite transmembrane transporter activity
B	0015650	molecular_function	lactate:proton symporter activity
B	0015706	biological_process	nitrate transmembrane transport
B	0015707	biological_process	nitrite transport
B	0016020	cellular_component	membrane
B	0022857	molecular_function	transmembrane transporter activity
B	0035873	biological_process	lactate transmembrane transport
B	0055085	biological_process	transmembrane transport
C	0005886	cellular_component	plasma membrane
C	0015513	molecular_function	high-affinity secondary active nitrite transmembrane transporter activity
C	0015650	molecular_function	lactate:proton symporter activity
C	0015706	biological_process	nitrate transmembrane transport
C	0015707	biological_process	nitrite transport
C	0016020	cellular_component	membrane
C	0022857	molecular_function	transmembrane transporter activity
C	0035873	biological_process	lactate transmembrane transport
C	0055085	biological_process	transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0015513	molecular_function	high-affinity secondary active nitrite transmembrane transporter activity
D	0015650	molecular_function	lactate:proton symporter activity
D	0015706	biological_process	nitrate transmembrane transport
D	0015707	biological_process	nitrite transport
D	0016020	cellular_component	membrane
D	0022857	molecular_function	transmembrane transporter activity
D	0035873	biological_process	lactate transmembrane transport
D	0055085	biological_process	transmembrane transport
E	0005886	cellular_component	plasma membrane
E	0015513	molecular_function	high-affinity secondary active nitrite transmembrane transporter activity
E	0015650	molecular_function	lactate:proton symporter activity
E	0015706	biological_process	nitrate transmembrane transport
E	0015707	biological_process	nitrite transport
E	0016020	cellular_component	membrane
E	0022857	molecular_function	transmembrane transporter activity
E	0035873	biological_process	lactate transmembrane transport
E	0055085	biological_process	transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue HV6 A 401

Chain	Residue
A	TYR31
A	GLY107
A	VAL196
A	VAL220
A	PHE223
A	HIS230
A	VAL54
A	PHE90
A	ALA93
A	PHE94
A	ILE97
A	ILE98
A	LEU104
A	THR106

---

site_id	AC2
Number of Residues	14
Details	binding site for residue HV6 B 401

Chain	Residue
B	TYR31
B	VAL54
B	PHE90
B	ALA93
B	PHE94
B	ILE97
B	ILE98
B	LEU104
B	THR106
B	GLY107
B	VAL196
B	VAL220
B	PHE223
B	HIS230

---

site_id	AC3
Number of Residues	14
Details	binding site for residue HV6 C 401

Chain	Residue
C	TYR31
C	VAL54
C	PHE90
C	ALA93
C	PHE94
C	ILE97
C	ILE98
C	LEU104
C	THR106
C	GLY107
C	VAL196
C	VAL220
C	PHE223
C	HIS230

---

site_id	AC4
Number of Residues	14
Details	binding site for residue HV6 D 401

Chain	Residue
D	TYR31
D	VAL54
D	PHE90
D	ALA93
D	PHE94
D	ILE97
D	ILE98
D	LEU104
D	THR106
D	GLY107
D	VAL196
D	VAL220
D	PHE223
D	HIS230

---

site_id	AC5
Number of Residues	14
Details	binding site for residue HV6 E 401

Chain	Residue
E	TYR31
E	VAL54
E	PHE90
E	ALA93
E	PHE94
E	ILE97
E	ILE98
E	LEU104
E	THR106
E	GLY107
E	VAL196
E	VAL220
E	PHE223
E	HIS230

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Functional Information from PROSITE/UniProt

site_id	PS01006
Number of Residues	11
Details	FORMATE_NITRITE_TP_2 Formate and nitrite transporters signature 2. AvgCNIFVCLA

Chain	Residue	Details
A	ALA189-ALA199

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