7E13
Caprylic acid targets a serine hydroxymethyltransferase to kill horseweed
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
A | 0019264 | biological_process | glycine biosynthetic process from serine |
A | 0030170 | molecular_function | pyridoxal phosphate binding |
A | 0035999 | biological_process | tetrahydrofolate interconversion |
B | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
B | 0019264 | biological_process | glycine biosynthetic process from serine |
B | 0030170 | molecular_function | pyridoxal phosphate binding |
B | 0035999 | biological_process | tetrahydrofolate interconversion |
C | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
C | 0019264 | biological_process | glycine biosynthetic process from serine |
C | 0030170 | molecular_function | pyridoxal phosphate binding |
C | 0035999 | biological_process | tetrahydrofolate interconversion |
D | 0004372 | molecular_function | glycine hydroxymethyltransferase activity |
D | 0019264 | biological_process | glycine biosynthetic process from serine |
D | 0030170 | molecular_function | pyridoxal phosphate binding |
D | 0035999 | biological_process | tetrahydrofolate interconversion |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | binding site for residue PLP A 601 |
Chain | Residue |
A | SER144 |
A | THR279 |
A | HIS281 |
A | LYS282 |
B | TYR98 |
B | GLY326 |
B | GLY327 |
A | GLY145 |
A | SER146 |
A | HIS173 |
A | SER175 |
A | SER228 |
A | ASP253 |
A | ALA255 |
A | HIS256 |
site_id | AC2 |
Number of Residues | 15 |
Details | binding site for residue PLP B 601 |
Chain | Residue |
A | TYR98 |
A | GLY326 |
A | GLY327 |
B | SER144 |
B | GLY145 |
B | SER146 |
B | HIS173 |
B | ALA227 |
B | SER228 |
B | ASP253 |
B | ALA255 |
B | HIS256 |
B | THR279 |
B | HIS281 |
B | LYS282 |
site_id | AC3 |
Number of Residues | 15 |
Details | binding site for residue PLP C 601 |
Chain | Residue |
C | SER144 |
C | GLY145 |
C | SER146 |
C | HIS173 |
C | ALA227 |
C | SER228 |
C | ASP253 |
C | ALA255 |
C | HIS256 |
C | THR279 |
C | HIS281 |
C | LYS282 |
D | TYR98 |
D | GLY326 |
D | GLY327 |
Functional Information from PROSITE/UniProt
site_id | PS00096 |
Number of Residues | 17 |
Details | SHMT Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. DVvTTTTHKSLrGPRGA |
Chain | Residue | Details |
A | ASP274-ALA290 |