7DYR

CryoEM Structure of Mannose Transporter ManYZ and Microcin E492 (MceA) complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006811	biological_process	monoatomic ion transport
A	0031640	biological_process	killing of cells of another organism
A	0034220	biological_process	monoatomic ion transmembrane transport
A	0042742	biological_process	defense response to bacterium
B	0005886	cellular_component	plasma membrane
B	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
B	0015761	biological_process	mannose transmembrane transport
B	0015764	biological_process	N-acetylglucosamine transport
B	0016020	cellular_component	membrane
B	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
B	0098708	biological_process	D-glucose import across plasma membrane
B	1990539	biological_process	fructose import across plasma membrane
C	0005886	cellular_component	plasma membrane
C	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
C	0015761	biological_process	mannose transmembrane transport
C	0015764	biological_process	N-acetylglucosamine transport
C	0016020	cellular_component	membrane
C	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
C	0098708	biological_process	D-glucose import across plasma membrane
C	1990539	biological_process	fructose import across plasma membrane
D	0006811	biological_process	monoatomic ion transport
D	0031640	biological_process	killing of cells of another organism
D	0034220	biological_process	monoatomic ion transmembrane transport
D	0042742	biological_process	defense response to bacterium
E	0005886	cellular_component	plasma membrane
E	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
E	0015761	biological_process	mannose transmembrane transport
E	0015764	biological_process	N-acetylglucosamine transport
E	0016020	cellular_component	membrane
E	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
E	0098708	biological_process	D-glucose import across plasma membrane
E	1990539	biological_process	fructose import across plasma membrane
F	0005886	cellular_component	plasma membrane
F	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
F	0015761	biological_process	mannose transmembrane transport
F	0015764	biological_process	N-acetylglucosamine transport
F	0016020	cellular_component	membrane
F	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
F	0098708	biological_process	D-glucose import across plasma membrane
F	1990539	biological_process	fructose import across plasma membrane
G	0006811	biological_process	monoatomic ion transport
G	0031640	biological_process	killing of cells of another organism
G	0034220	biological_process	monoatomic ion transmembrane transport
G	0042742	biological_process	defense response to bacterium
Y	0005886	cellular_component	plasma membrane
Y	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
Y	0015761	biological_process	mannose transmembrane transport
Y	0015764	biological_process	N-acetylglucosamine transport
Y	0016020	cellular_component	membrane
Y	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
Y	0098708	biological_process	D-glucose import across plasma membrane
Y	1990539	biological_process	fructose import across plasma membrane
Z	0005886	cellular_component	plasma membrane
Z	0009401	biological_process	phosphoenolpyruvate-dependent sugar phosphotransferase system
Z	0015761	biological_process	mannose transmembrane transport
Z	0015764	biological_process	N-acetylglucosamine transport
Z	0016020	cellular_component	membrane
Z	0022870	molecular_function	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity
Z	0098708	biological_process	D-glucose import across plasma membrane
Z	1990539	biological_process	fructose import across plasma membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"31209249","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32710850","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	438
Details	Intramembrane: {"evidences":[{"source":"PubMed","id":"32710850","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	177
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"32710850","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	699
Details	Transmembrane: {"evidences":[{"source":"PubMed","id":"32710850","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	120
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"32710850","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	702
Details	Domain: {"description":"PTS EIIC type-4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00429","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	3
Details	Modified residue: {"description":"N-formylmethionine","evidences":[{"source":"PubMed","id":"2951378","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	6
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"15919996","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31209249","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"8774730","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"32710850","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	810
Details	Domain: {"description":"PTS EIID","evidences":[{"source":"PROSITE-ProRule","id":"PRU00431","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---