7DPR
E. coli GyrB ATPase domain in complex with methyl 3,4-dihydroxybenzoate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006265 | biological_process | DNA topological change |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003918 | molecular_function | DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue HE9 A 301 |
| Chain | Residue |
| A | VAL43 |
| A | ASN46 |
| A | ALA47 |
| A | VAL71 |
| A | ASP73 |
| A | ILE94 |
| A | VAL120 |
| A | THR165 |
| A | VAL167 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue AX7 A 302 |
| Chain | Residue |
| A | HIS147 |
| A | GLU174 |
| B | ARG20 |
| B | HIS147 |
| B | GLU174 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 303 |
| Chain | Residue |
| A | HIS64 |
| A | ARG168 |
| A | LYS208 |
| A | HOH426 |
| A | HOH451 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 A 304 |
| Chain | Residue |
| A | ARG20 |
| A | LYS21 |
| A | PRO23 |
| A | HOH405 |
| B | PRO150 |
| B | GLN151 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 A 305 |
| Chain | Residue |
| A | SER195 |
| A | HIS215 |
| A | PHE216 |
| A | HIS217 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue HE9 B 301 |
| Chain | Residue |
| B | VAL43 |
| B | ASN46 |
| B | ALA47 |
| B | GLU50 |
| B | VAL71 |
| B | ASP73 |
| B | ILE94 |
| B | MET95 |
| B | VAL120 |
| B | THR165 |
| B | VAL167 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue PO4 B 302 |
| Chain | Residue |
| B | HIS55 |
| B | HIS64 |
| B | ARG76 |
| B | ARG168 |
| B | LYS208 |
| B | HOH434 |
| B | HOH472 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 B 303 |
| Chain | Residue |
| A | GLN151 |
| B | ARG20 |
| B | LYS21 |
| B | PRO23 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor (ATPase activity)","evidences":[{"source":"PubMed","id":"10734094","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"8248233","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10734094","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25202966","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25849408","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"25849408","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
