7DOA
Crystal structure of Catabolite repressor acivator from E. coli in complex with HEPES
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0006351 | biological_process | DNA-templated transcription |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0009750 | biological_process | response to fructose |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0006351 | biological_process | DNA-templated transcription |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0009750 | biological_process | response to fructose |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EPE A 401 |
| Chain | Residue |
| A | SER75 |
| A | ARG197 |
| A | GLY274 |
| A | VAL289 |
| A | ALA290 |
| A | GLN291 |
| A | ARG323 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue EPE B 401 |
| Chain | Residue |
| B | SER246 |
| B | PHE247 |
| B | GLY274 |
| B | GLN291 |
| B | ARG323 |
| B | SER75 |
| B | ARG197 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EPE B 402 |
| Chain | Residue |
| A | LEU278 |
| A | PHE281 |
| A | GLN283 |
| B | LEU264 |
| B | LEU278 |
| B | GLN283 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 403 |
| Chain | Residue |
| A | LYS176 |
| A | ARG327 |
| B | TYR82 |
| B | ARG85 |
Functional Information from PROSITE/UniProt
| site_id | PS00356 |
| Number of Residues | 19 |
| Details | HTH_LACI_1 LacI-type HTH domain signature. LdEIArlAgVSrtTAsyVI |
| Chain | Residue | Details |
| A | LEU3-ILE21 |
