7DNU

mRNA-decapping enzyme g5Rp with inhibitor insp6 complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003824	molecular_function	catalytic activity
A	0004081	molecular_function	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity
A	0006167	biological_process	AMP biosynthetic process
A	0006754	biological_process	ATP biosynthetic process
A	0008486	molecular_function	diphosphoinositol-polyphosphate diphosphatase activity
A	0016787	molecular_function	hydrolase activity
A	0039657	biological_process	symbiont-mediated suppression of host gene expression
A	0044168	cellular_component	host cell rough endoplasmic reticulum
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	binding site for residue IHP A 301

Chain	Residue
A	GLN6
A	LYS8
A	LYS94
A	LYS95
A	LYS98
A	LYS133

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Functional Information from PROSITE/UniProt

site_id	PS00893
Number of Residues	22
Details	NUDIX_BOX Nudix box signature. GkpkedEsdltCAiREFeEEtG

Chain	Residue	Details
A	GLY132-GLY153

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	142
Details	Domain: {"description":"Nudix hydrolase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00794","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	21
Details	Motif: {"description":"Nudix box","evidences":[{"source":"PROSITE-ProRule","id":"PRU00794","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"19695654","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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