7DNR

Crystal Structure of Zn-bound SIS Domain of Glucosamine-6-P Synthase from E. coli

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004360	molecular_function	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A	0097367	molecular_function	carbohydrate derivative binding
A	1901135	biological_process	carbohydrate derivative metabolic process
A	1901137	biological_process	carbohydrate derivative biosynthetic process
B	0004360	molecular_function	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B	0097367	molecular_function	carbohydrate derivative binding
B	1901135	biological_process	carbohydrate derivative metabolic process
B	1901137	biological_process	carbohydrate derivative biosynthetic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: For Fru-6P isomerization activity

Chain	Residue	Details
A	LYS604
B	LYS604

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 82

Chain	Residue	Details
A	GLU482	electrostatic stabiliser, hydrogen bond acceptor
A	LYS486	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	GLU489	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
A	HIS505	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

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site_id	MCSA2
Number of Residues	4
Details	M-CSA 82

Chain	Residue	Details
B	GLU482	electrostatic stabiliser, hydrogen bond acceptor
B	LYS486	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
B	GLU489	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor
B	HIS505	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor

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