7DMG
Short chain dehydrogenase 2 (SCR2) crystal structure with NADP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004090 | molecular_function | carbonyl reductase (NADPH) activity |
| A | 0005575 | cellular_component | cellular_component |
| A | 0008150 | biological_process | biological_process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0050664 | molecular_function | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004090 | molecular_function | carbonyl reductase (NADPH) activity |
| B | 0005575 | cellular_component | cellular_component |
| B | 0008150 | biological_process | biological_process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0050664 | molecular_function | oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 35 |
| Details | binding site for residue NAP A 301 |
| Chain | Residue |
| A | GLY41 |
| A | ASN91 |
| A | ILE92 |
| A | ASN118 |
| A | ALA119 |
| A | GLY120 |
| A | VAL121 |
| A | LEU143 |
| A | THR170 |
| A | SER171 |
| A | SER172 |
| A | SER43 |
| A | TYR187 |
| A | LYS191 |
| A | PRO216 |
| A | GLY217 |
| A | TYR218 |
| A | ILE219 |
| A | THR221 |
| A | HOH401 |
| A | HOH402 |
| A | HOH427 |
| A | GLY44 |
| A | HOH433 |
| A | HOH465 |
| A | HOH468 |
| A | HOH471 |
| A | HOH477 |
| A | HOH493 |
| A | GLY45 |
| A | ILE46 |
| A | ASN66 |
| A | SER67 |
| A | HIS68 |
| A | CYS90 |
| site_id | AC2 |
| Number of Residues | 33 |
| Details | binding site for residue NAP B 301 |
| Chain | Residue |
| B | GLY41 |
| B | SER43 |
| B | GLY44 |
| B | GLY45 |
| B | ILE46 |
| B | ASN66 |
| B | SER67 |
| B | HIS68 |
| B | CYS90 |
| B | ASN91 |
| B | ILE92 |
| B | ASN118 |
| B | ALA119 |
| B | GLY120 |
| B | VAL121 |
| B | LEU143 |
| B | THR170 |
| B | SER171 |
| B | SER172 |
| B | TYR187 |
| B | LYS191 |
| B | PRO216 |
| B | GLY217 |
| B | ILE219 |
| B | HOH404 |
| B | HOH422 |
| B | HOH443 |
| B | HOH444 |
| B | HOH477 |
| B | HOH492 |
| B | HOH497 |
| B | HOH528 |
| B | HOH545 |
