7DGQ

Activity optimized supercomplex state1

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0003954	molecular_function	NADH dehydrogenase activity
1	0005739	cellular_component	mitochondrion
1	0005743	cellular_component	mitochondrial inner membrane
1	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
1	0009060	biological_process	aerobic respiration
1	0016020	cellular_component	membrane
1	0032981	biological_process	mitochondrial respiratory chain complex I assembly
1	0045271	cellular_component	respiratory chain complex I
1	1902600	biological_process	proton transmembrane transport
2	0005739	cellular_component	mitochondrion
2	0005743	cellular_component	mitochondrial inner membrane
2	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
2	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
2	0032981	biological_process	mitochondrial respiratory chain complex I assembly
2	0045271	cellular_component	respiratory chain complex I
2	1902600	biological_process	proton transmembrane transport
3	0005739	cellular_component	mitochondrion
3	0005743	cellular_component	mitochondrial inner membrane
3	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
3	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
3	0045271	cellular_component	respiratory chain complex I
3	1902600	biological_process	proton transmembrane transport
4	0003954	molecular_function	NADH dehydrogenase activity
4	0005739	cellular_component	mitochondrion
4	0005743	cellular_component	mitochondrial inner membrane
4	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
4	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
4	0009060	biological_process	aerobic respiration
4	0015990	biological_process	electron transport coupled proton transport
4	0032981	biological_process	mitochondrial respiratory chain complex I assembly
4	0042773	biological_process	ATP synthesis coupled electron transport
4	0045271	cellular_component	respiratory chain complex I
4	0048039	molecular_function	ubiquinone binding
5	0005739	cellular_component	mitochondrion
5	0005743	cellular_component	mitochondrial inner membrane
5	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
5	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
5	0042773	biological_process	ATP synthesis coupled electron transport
5	0045271	cellular_component	respiratory chain complex I
5	1902600	biological_process	proton transmembrane transport
6	0003954	molecular_function	NADH dehydrogenase activity
6	0005739	cellular_component	mitochondrion
6	0005743	cellular_component	mitochondrial inner membrane
6	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
6	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
6	0015990	biological_process	electron transport coupled proton transport
6	0032981	biological_process	mitochondrial respiratory chain complex I assembly
6	0042773	biological_process	ATP synthesis coupled electron transport
6	0045271	cellular_component	respiratory chain complex I
7	0005739	cellular_component	mitochondrion
7	0005743	cellular_component	mitochondrial inner membrane
7	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
7	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
7	0032981	biological_process	mitochondrial respiratory chain complex I assembly
7	1902600	biological_process	proton transmembrane transport
8	0005739	cellular_component	mitochondrion
8	0005743	cellular_component	mitochondrial inner membrane
8	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
8	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
8	0010181	molecular_function	FMN binding
8	0016491	molecular_function	oxidoreductase activity
8	0045271	cellular_component	respiratory chain complex I
8	0046872	molecular_function	metal ion binding
8	0051287	molecular_function	NAD binding
8	0051539	molecular_function	4 iron, 4 sulfur cluster binding
8	1902600	biological_process	proton transmembrane transport
9	0016491	molecular_function	oxidoreductase activity
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0005758	cellular_component	mitochondrial intermembrane space
A	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0009055	molecular_function	electron transfer activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
A	0032981	biological_process	mitochondrial respiratory chain complex I assembly
A	0042773	biological_process	ATP synthesis coupled electron transport
A	0045271	cellular_component	respiratory chain complex I
A	0045333	biological_process	cellular respiration
A	0046872	molecular_function	metal ion binding
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	1902600	biological_process	proton transmembrane transport
A0	0005739	cellular_component	mitochondrion
A0	0005743	cellular_component	mitochondrial inner membrane
A0	0006119	biological_process	oxidative phosphorylation
A0	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
A0	0045277	cellular_component	respiratory chain complex IV
A1	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
A1	0016020	cellular_component	membrane
A1	0051537	molecular_function	2 iron, 2 sulfur cluster binding
A2	0005739	cellular_component	mitochondrion
A2	0005743	cellular_component	mitochondrial inner membrane
A2	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
A2	0045275	cellular_component	respiratory chain complex III
A3	0005739	cellular_component	mitochondrion
A3	0005743	cellular_component	mitochondrial inner membrane
A3	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
A3	0045275	cellular_component	respiratory chain complex III
A4	0005739	cellular_component	mitochondrion
A4	0005743	cellular_component	mitochondrial inner membrane
A4	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
A5	0005739	cellular_component	mitochondrion
A5	0005740	cellular_component	mitochondrial envelope
A5	0005743	cellular_component	mitochondrial inner membrane
A5	0006119	biological_process	oxidative phosphorylation
A5	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
A5	0045277	cellular_component	respiratory chain complex IV
A5	0046872	molecular_function	metal ion binding
A6	0005739	cellular_component	mitochondrion
A6	0005743	cellular_component	mitochondrial inner membrane
A6	0006119	biological_process	oxidative phosphorylation
A6	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
A6	0016491	molecular_function	oxidoreductase activity
A6	0030234	molecular_function	enzyme regulator activity
A6	0045277	cellular_component	respiratory chain complex IV
A7	0004129	molecular_function	cytochrome-c oxidase activity
A7	0005739	cellular_component	mitochondrion
A7	0005743	cellular_component	mitochondrial inner membrane
A7	0006119	biological_process	oxidative phosphorylation
A7	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
A7	0045277	cellular_component	respiratory chain complex IV
A7	1902600	biological_process	proton transmembrane transport
A8	0005739	cellular_component	mitochondrion
A8	0005743	cellular_component	mitochondrial inner membrane
A8	0006119	biological_process	oxidative phosphorylation
A8	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
A8	0045277	cellular_component	respiratory chain complex IV
A9	0004129	molecular_function	cytochrome-c oxidase activity
A9	0005739	cellular_component	mitochondrion
A9	0005743	cellular_component	mitochondrial inner membrane
A9	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
A9	0008535	biological_process	respiratory chain complex IV assembly
A9	0009055	molecular_function	electron transfer activity
A9	0016020	cellular_component	membrane
A9	0019646	biological_process	aerobic electron transport chain
A9	0022904	biological_process	respiratory electron transport chain
A9	0045277	cellular_component	respiratory chain complex IV
A9	1902600	biological_process	proton transmembrane transport
B	0003954	molecular_function	NADH dehydrogenase activity
B	0005654	cellular_component	nucleoplasm
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
B	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
B	0016491	molecular_function	oxidoreductase activity
B	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
B	0019826	molecular_function	oxygen sensor activity
B	0022008	biological_process	neurogenesis
B	0031625	molecular_function	ubiquitin protein ligase binding
B	0032981	biological_process	mitochondrial respiratory chain complex I assembly
B	0042063	biological_process	gliogenesis
B	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
B	0045271	cellular_component	respiratory chain complex I
B	0046872	molecular_function	metal ion binding
B	0048038	molecular_function	quinone binding
B	0051287	molecular_function	NAD binding
B	0051539	molecular_function	4 iron, 4 sulfur cluster binding
B	0061351	biological_process	neural precursor cell proliferation
B	0071453	biological_process	cellular response to oxygen levels
B	1902600	biological_process	proton transmembrane transport
B2	0002082	biological_process	regulation of oxidative phosphorylation
B2	0005739	cellular_component	mitochondrion
B2	0005743	cellular_component	mitochondrial inner membrane
B2	0006119	biological_process	oxidative phosphorylation
B2	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
B2	0016491	molecular_function	oxidoreductase activity
B2	0045277	cellular_component	respiratory chain complex IV
B2	0097250	biological_process	mitochondrial respirasome assembly
B2	0098803	cellular_component	respiratory chain complex
B3	0005739	cellular_component	mitochondrion
B3	0005743	cellular_component	mitochondrial inner membrane
B3	0006119	biological_process	oxidative phosphorylation
B3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
B3	0007417	biological_process	central nervous system development
B3	0045277	cellular_component	respiratory chain complex IV
B4	0004129	molecular_function	cytochrome-c oxidase activity
B4	0005739	cellular_component	mitochondrion
B4	0005743	cellular_component	mitochondrial inner membrane
B4	0006119	biological_process	oxidative phosphorylation
B4	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
B4	0045277	cellular_component	respiratory chain complex IV
B4	0046872	molecular_function	metal ion binding
B4	1902600	biological_process	proton transmembrane transport
B5	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
B6	0005739	cellular_component	mitochondrion
B6	0005743	cellular_component	mitochondrial inner membrane
B6	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
B6	0045275	cellular_component	respiratory chain complex III
B7	0005739	cellular_component	mitochondrion
B7	0005743	cellular_component	mitochondrial inner membrane
B7	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
B7	0045275	cellular_component	respiratory chain complex III
C	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
C	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
C0	0005739	cellular_component	mitochondrion
C0	0005743	cellular_component	mitochondrial inner membrane
C0	0006119	biological_process	oxidative phosphorylation
C0	0045277	cellular_component	respiratory chain complex IV
C1	0004129	molecular_function	cytochrome-c oxidase activity
C1	0005507	molecular_function	copper ion binding
C1	0005739	cellular_component	mitochondrion
C1	0005743	cellular_component	mitochondrial inner membrane
C1	0016020	cellular_component	membrane
C1	0016491	molecular_function	oxidoreductase activity
C1	0022900	biological_process	electron transport chain
C1	0042773	biological_process	ATP synthesis coupled electron transport
C1	0045277	cellular_component	respiratory chain complex IV
C1	0046872	molecular_function	metal ion binding
C1	1902600	biological_process	proton transmembrane transport
C2	0005739	cellular_component	mitochondrion
C2	0005743	cellular_component	mitochondrial inner membrane
C2	0006119	biological_process	oxidative phosphorylation
C2	0045277	cellular_component	respiratory chain complex IV
C3	0004129	molecular_function	cytochrome-c oxidase activity
C3	0005739	cellular_component	mitochondrion
C3	0005743	cellular_component	mitochondrial inner membrane
C3	0006119	biological_process	oxidative phosphorylation
C3	0006123	biological_process	mitochondrial electron transport, cytochrome c to oxygen
C3	0009060	biological_process	aerobic respiration
C3	0015990	biological_process	electron transport coupled proton transport
C3	0016020	cellular_component	membrane
C3	0020037	molecular_function	heme binding
C3	0045277	cellular_component	respiratory chain complex IV
C3	0046872	molecular_function	metal ion binding
D	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
D	0048038	molecular_function	quinone binding
D	0051536	molecular_function	iron-sulfur cluster binding
D	0051539	molecular_function	4 iron, 4 sulfur cluster binding
E	0016020	cellular_component	membrane
E	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
E	0051539	molecular_function	4 iron, 4 sulfur cluster binding
F	0005739	cellular_component	mitochondrion
F	0045271	cellular_component	respiratory chain complex I
G	0022900	biological_process	electron transport chain
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005758	cellular_component	mitochondrial intermembrane space
H	0032981	biological_process	mitochondrial respiratory chain complex I assembly
H	0045271	cellular_component	respiratory chain complex I
I	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0032981	biological_process	mitochondrial respiratory chain complex I assembly
J	0045271	cellular_component	respiratory chain complex I
K	0005739	cellular_component	mitochondrion
K	0005743	cellular_component	mitochondrial inner membrane
K	0031966	cellular_component	mitochondrial membrane
K	0032981	biological_process	mitochondrial respiratory chain complex I assembly
K	0045271	cellular_component	respiratory chain complex I
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0032981	biological_process	mitochondrial respiratory chain complex I assembly
L	0045271	cellular_component	respiratory chain complex I
M	0006633	biological_process	fatty acid biosynthetic process
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0022904	biological_process	respiratory electron transport chain
N	0032981	biological_process	mitochondrial respiratory chain complex I assembly
N	0045271	cellular_component	respiratory chain complex I
O	0005739	cellular_component	mitochondrion
O	0005743	cellular_component	mitochondrial inner membrane
O	0006979	biological_process	response to oxidative stress
O	0032981	biological_process	mitochondrial respiratory chain complex I assembly
O	0045271	cellular_component	respiratory chain complex I
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
P	0016491	molecular_function	oxidoreductase activity
P	0042773	biological_process	ATP synthesis coupled electron transport
P	0045271	cellular_component	respiratory chain complex I
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005758	cellular_component	mitochondrial intermembrane space
Q	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
Q	0032981	biological_process	mitochondrial respiratory chain complex I assembly
Q	0045271	cellular_component	respiratory chain complex I
R	0005739	cellular_component	mitochondrion
R	0005759	cellular_component	mitochondrial matrix
R	0032981	biological_process	mitochondrial respiratory chain complex I assembly
R	0044877	molecular_function	protein-containing complex binding
R	0045271	cellular_component	respiratory chain complex I
R	1901006	biological_process	ubiquinone-6 biosynthetic process
S	0005737	cellular_component	cytoplasm
S	0005739	cellular_component	mitochondrion
S	0005759	cellular_component	mitochondrial matrix
S	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
S	0032981	biological_process	mitochondrial respiratory chain complex I assembly
S	0045271	cellular_component	respiratory chain complex I
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0032981	biological_process	mitochondrial respiratory chain complex I assembly
T	0045271	cellular_component	respiratory chain complex I
U	0005739	cellular_component	mitochondrion
U	0005743	cellular_component	mitochondrial inner membrane
U	0006979	biological_process	response to oxidative stress
U	0016020	cellular_component	membrane
U	0032981	biological_process	mitochondrial respiratory chain complex I assembly
U	0045271	cellular_component	respiratory chain complex I
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005737	cellular_component	cytoplasm
V	0005739	cellular_component	mitochondrion
V	0005743	cellular_component	mitochondrial inner membrane
V	0006915	biological_process	apoptotic process
V	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
V	0032981	biological_process	mitochondrial respiratory chain complex I assembly
V	0045271	cellular_component	respiratory chain complex I
V	0045892	biological_process	negative regulation of DNA-templated transcription
V	1902600	biological_process	proton transmembrane transport
W	0006633	biological_process	fatty acid biosynthetic process
X	0005739	cellular_component	mitochondrion
X	0005743	cellular_component	mitochondrial inner membrane
X	0032981	biological_process	mitochondrial respiratory chain complex I assembly
X	0045271	cellular_component	respiratory chain complex I
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0045271	cellular_component	respiratory chain complex I
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0022900	biological_process	electron transport chain
Z	0032981	biological_process	mitochondrial respiratory chain complex I assembly
Z	0045271	cellular_component	respiratory chain complex I
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0032981	biological_process	mitochondrial respiratory chain complex I assembly
a	0045271	cellular_component	respiratory chain complex I
c	0005654	cellular_component	nucleoplasm
c	0005739	cellular_component	mitochondrion
c	0005743	cellular_component	mitochondrial inner membrane
c	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
c	0031966	cellular_component	mitochondrial membrane
c	0032981	biological_process	mitochondrial respiratory chain complex I assembly
c	0042775	biological_process	mitochondrial ATP synthesis coupled electron transport
c	0045271	cellular_component	respiratory chain complex I
d	0005739	cellular_component	mitochondrion
e	0005739	cellular_component	mitochondrion
e	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
f	0005739	cellular_component	mitochondrion
f	0005743	cellular_component	mitochondrial inner membrane
f	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
f	0032981	biological_process	mitochondrial respiratory chain complex I assembly
f	0045271	cellular_component	respiratory chain complex I
g	0005739	cellular_component	mitochondrion
g	0005743	cellular_component	mitochondrial inner membrane
g	0032981	biological_process	mitochondrial respiratory chain complex I assembly
g	0045271	cellular_component	respiratory chain complex I
i	0005739	cellular_component	mitochondrion
i	0045271	cellular_component	respiratory chain complex I
j	0005739	cellular_component	mitochondrion
j	0005743	cellular_component	mitochondrial inner membrane
j	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
j	0032981	biological_process	mitochondrial respiratory chain complex I assembly
j	0045271	cellular_component	respiratory chain complex I
k	0005739	cellular_component	mitochondrion
k	0005743	cellular_component	mitochondrial inner membrane
k	0046872	molecular_function	metal ion binding
l	0004222	molecular_function	metalloendopeptidase activity
l	0005739	cellular_component	mitochondrion
l	0005743	cellular_component	mitochondrial inner membrane
l	0006508	biological_process	proteolysis
l	0046872	molecular_function	metal ion binding
m	0005739	cellular_component	mitochondrion
m	0005743	cellular_component	mitochondrial inner membrane
m	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
m	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
m	0009055	molecular_function	electron transfer activity
m	0016020	cellular_component	membrane
m	0016491	molecular_function	oxidoreductase activity
m	0020037	molecular_function	heme binding
m	0022904	biological_process	respiratory electron transport chain
m	0031966	cellular_component	mitochondrial membrane
m	0045275	cellular_component	respiratory chain complex III
m	0046872	molecular_function	metal ion binding
m	0048039	molecular_function	ubiquinone binding
m	1902600	biological_process	proton transmembrane transport
o	0005739	cellular_component	mitochondrion
o	0005743	cellular_component	mitochondrial inner membrane
o	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
o	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
o	0009055	molecular_function	electron transfer activity
o	0020037	molecular_function	heme binding
o	0045275	cellular_component	respiratory chain complex III
o	0046872	molecular_function	metal ion binding
o	1902600	biological_process	proton transmembrane transport
p	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
p	0016020	cellular_component	membrane
p	0051537	molecular_function	2 iron, 2 sulfur cluster binding
q	0005739	cellular_component	mitochondrion
q	0005743	cellular_component	mitochondrial inner membrane
q	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
q	0045275	cellular_component	respiratory chain complex III
r	0005739	cellular_component	mitochondrion
r	0005743	cellular_component	mitochondrial inner membrane
r	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
r	0045275	cellular_component	respiratory chain complex III
s	0005739	cellular_component	mitochondrion
s	0005743	cellular_component	mitochondrial inner membrane
s	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
s	0045275	cellular_component	respiratory chain complex III
t	0005739	cellular_component	mitochondrion
t	0005743	cellular_component	mitochondrial inner membrane
t	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
u	0005739	cellular_component	mitochondrion
u	0005743	cellular_component	mitochondrial inner membrane
u	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
u	0045275	cellular_component	respiratory chain complex III
v	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
w	0005739	cellular_component	mitochondrion
w	0005743	cellular_component	mitochondrial inner membrane
w	0046872	molecular_function	metal ion binding
x	0004222	molecular_function	metalloendopeptidase activity
x	0005739	cellular_component	mitochondrion
x	0005743	cellular_component	mitochondrial inner membrane
x	0006508	biological_process	proteolysis
x	0046872	molecular_function	metal ion binding
y	0005739	cellular_component	mitochondrion
y	0005743	cellular_component	mitochondrial inner membrane
y	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
y	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
y	0009055	molecular_function	electron transfer activity
y	0016020	cellular_component	membrane
y	0016491	molecular_function	oxidoreductase activity
y	0020037	molecular_function	heme binding
y	0022904	biological_process	respiratory electron transport chain
y	0031966	cellular_component	mitochondrial membrane
y	0045275	cellular_component	respiratory chain complex III
y	0046872	molecular_function	metal ion binding
y	0048039	molecular_function	ubiquinone binding
y	1902600	biological_process	proton transmembrane transport
z	0005739	cellular_component	mitochondrion
z	0005743	cellular_component	mitochondrial inner membrane
z	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
z	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
z	0009055	molecular_function	electron transfer activity
z	0020037	molecular_function	heme binding
z	0045275	cellular_component	respiratory chain complex III
z	0046872	molecular_function	metal ion binding
z	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue PC1 3 200

Chain	Residue
1	MET302
3	ALA99
3	TRP106
L	VAL12
L	GLU16
L	LEU19
L	PHE23

---

site_id	AC2
Number of Residues	12
Details	binding site for residue 3PE 1 401

Chain	Residue
3	LEU7
3	PHE11
7	ILE34
7	GLY38
7	VAL39
7	SER50
7	LEU54
7	PHE57
J	ALA39
V	PHE140
1	MET98
1	ASN99

---

site_id	AC3
Number of Residues	7
Details	binding site for residue FES 9 301

Chain	Residue
9	CYS135
9	THR137
9	CYS140
9	CYS176
9	LEU177
9	ALA179
9	CYS180

---

site_id	AC4
Number of Residues	6
Details	binding site for residue 3PE 4 501

Chain	Residue
2	ILE276
2	ILE277
4	TYR166
4	SER191
4	ALA198
T	TRP133

---

site_id	AC5
Number of Residues	11
Details	binding site for residue CDL 6 701

Chain	Residue
4	PRO353
4	LEU354
4	ALA356
4	THR357
6	MET20
6	MET22
6	SER23
6	LYS116
6	LYS119
6	TYR120
b	LEU68

---

site_id	AC6
Number of Residues	4
Details	binding site for residue 3PE 2 401

Chain	Residue
2	PRO238
2	ILE239
4	TRP16
j	LEU43

---

site_id	AC7
Number of Residues	9
Details	binding site for residue PC1 2 402

Chain	Residue
2	SER126
2	ILE129
2	ILE210
2	SER213
2	THR217
2	LEU319
2	LYS321
2	LEU326
S	PRO28

---

site_id	AC8
Number of Residues	12
Details	binding site for residue FMN 8 501

Chain	Residue
8	ARG88
8	GLY89
8	LYS98
8	ASN116
8	ASP118
8	GLU119
8	GLY120
8	CYS206
8	GLY207
8	VAL242
8	ALA243
8	ASN244

---

site_id	AC9
Number of Residues	7
Details	binding site for residue SF4 8 502

Chain	Residue
8	TYR204
8	SER378
8	CYS379
8	GLY380
8	CYS382
8	CYS385
8	CYS425

---

site_id	AD1
Number of Residues	3
Details	binding site for residue CU C3 601

Chain	Residue
C3	HIS240
C3	HIS290
C3	HIS291

---

site_id	AD2
Number of Residues	23
Details	binding site for residue HEA C3 602

Chain	Residue
C3	ARG439
C3	MET468
C3	GLY27
C3	MET28
C3	SER34
C3	ILE37
C3	ARG38
C3	TYR54
C3	VAL58
C3	HIS61
C3	ALA62
C3	MET65
C3	ILE66
C3	VAL70
C3	GLY125
C3	TRP126
C3	TYR371
C3	PHE377
C3	HIS378
C3	SER382
C3	PHE425
C3	GLN428
C3	ARG438

---

site_id	AD3
Number of Residues	22
Details	binding site for residue HEA C3 603

Chain	Residue
C3	TRP126
C3	TRP236
C3	VAL243
C3	TYR244
C3	HIS290
C3	HIS291
C3	THR309
C3	ALA313
C3	THR316
C3	GLY317
C3	GLY352
C3	LEU353
C3	GLY355
C3	ILE356
C3	LEU358
C3	ALA359
C3	ASP364
C3	HIS368
C3	HIS376
C3	PHE377
C3	VAL380
C3	ARG438

---

site_id	AD4
Number of Residues	3
Details	binding site for residue MG C1 301

Chain	Residue
C1	GLU198
C3	HIS368
C3	ASP369

---

site_id	AD5
Number of Residues	5
Details	binding site for residue CU C1 302

Chain	Residue
C1	HIS161
C1	CYS196
C1	CYS200
C1	MET207
C1	CU303

---

site_id	AD6
Number of Residues	5
Details	binding site for residue CU C1 303

Chain	Residue
C1	CYS196
C1	GLU198
C1	CYS200
C1	HIS204
C1	CU302

---

site_id	AD7
Number of Residues	4
Details	binding site for residue ZN A5 101

Chain	Residue
A5	CYS60
A5	CYS62
A5	CYS82
A5	CYS85

---

site_id	AD8
Number of Residues	7
Details	binding site for residue SF4 A 801

Chain	Residue
A	HIS124
A	ASP127
A	CYS128
A	CYS131
A	CYS137
A	GLN140
A	ARG175

---

site_id	AD9
Number of Residues	9
Details	binding site for residue SF4 A 802

Chain	Residue
A	CYS176
A	GLN178
A	CYS179
A	THR180
A	ARG181
A	CYS182
A	CYS226
A	PRO227
A	ALA230

---

site_id	AE1
Number of Residues	8
Details	binding site for residue FES A 803

Chain	Residue
A	PHE63
A	CYS64
A	TYR65
A	ALA72
A	GLY73
A	CYS75
A	CYS78
A	CYS92

---

site_id	AE2
Number of Residues	11
Details	binding site for residue 3PE B 501

Chain	Residue
1	MET183
1	MET184
1	TYR277
1	ASN292
1	LEU296
B	ARG266
B	ASN270
E	LEU61
E	TRP63
L	ILE25
V	ILE40

---

site_id	AE3
Number of Residues	6
Details	binding site for residue SF4 D 301

Chain	Residue
D	ALA90
D	CYS91
D	CYS92
D	THR128
D	CYS156
D	CYS186

---

site_id	AE4
Number of Residues	8
Details	binding site for residue SF4 E 301

Chain	Residue
E	CYS123
E	PRO124
E	CYS152
E	ILE153
E	TYR154
E	CYS155
E	CYS158
E	GLU169

---

site_id	AE5
Number of Residues	8
Details	binding site for residue SF4 E 302

Chain	Residue
E	CYS113
E	ILE114
E	CYS116
E	LYS117
E	CYS119
E	TYR145
E	CYS162
E	ALA166

---

site_id	AE6
Number of Residues	3
Details	binding site for residue ZN I 300

Chain	Residue
I	CYS87
I	HIS96
I	CYS115

---

site_id	AE7
Number of Residues	12
Details	binding site for residue CDL J 101

Chain	Residue
J	TRP2
J	PHE3
J	LEU6
P	ARG6
P	PHE7
P	ILE8
U	GLU2
U	LEU3
U	VAL6
U	LEU7
U	GLN13
U	ARG34

---

site_id	AE8
Number of Residues	6
Details	binding site for residue PC1 Q 201

Chain	Residue
2	PRO256
2	MET335
4	LEU55
Q	TRP170
Q	THR171
Q	MET172

---

site_id	AE9
Number of Residues	17
Details	binding site for residue NAP R 601

Chain	Residue
D	ARG215
R	THR62
R	GLY63
R	LEU65
R	ARG85
R	GLU87
R	LEU129
R	VAL130
R	GLY131
R	ARG132
R	VAL144
R	ILE167
R	SER168
R	TYR180
R	PRO203
R	ALA204
R	ILE206

---

site_id	AF1
Number of Residues	2
Details	binding site for residue PC1 S 401

Chain	Residue
S	MET284
S	VAL286

---

site_id	AF2
Number of Residues	10
Details	binding site for residue CDL b 201

Chain	Residue
4	LEU447
4	LEU449
4	ASN450
6	SER23
6	TRP66
b	ALA83
b	ILE84
h	VAL106
h	ALA107
h	TYR108

---

site_id	AF3
Number of Residues	6
Details	binding site for residue PC1 j 201

Chain	Residue
H	PRO2
H	PHE4
H	VAL6
j	PHE11
j	GLN12
j	PHE13

---

site_id	AF4
Number of Residues	7
Details	binding site for residue 3PE j 202

Chain	Residue
2	THR324
2	MET329
j	LEU63
j	TYR64
j	SER67
j	PHE68
j	VAL71

---

site_id	AF5
Number of Residues	15
Details	binding site for residue HEM m 401

Chain	Residue
m	LEU41
m	GLN44
m	ILE45
m	GLY48
m	LEU49
m	LEU51
m	HIS83
m	ALA84
m	THR126
m	ALA127
m	GLY130
m	LEU133
m	PRO134
m	HIS182
m	PHE183

---

site_id	AF6
Number of Residues	16
Details	binding site for residue HEM m 402

Chain	Residue
m	TRP31
m	GLY34
m	LEU37
m	PHE90
m	LEU94
m	HIS97
m	ARG100
m	SER106
m	TRP113
m	GLY116
m	VAL117
m	LEU119
m	HIS196
m	LEU200
m	SER205
m	ASN206

---

site_id	AF7
Number of Residues	12
Details	binding site for residue HEC o 301

Chain	Residue
o	VAL36
o	CYS37
o	SER39
o	CYS40
o	HIS41
o	ASN105
o	LEU113
o	ARG120
o	ILE158
o	GLY159
o	MET160
o	PRO163

---

site_id	AF8
Number of Residues	15
Details	binding site for residue HEM y 401

Chain	Residue
y	LEU41
y	GLN44
y	ILE45
y	GLY48
y	LEU49
y	LEU51
y	HIS83
y	ALA84
y	THR126
y	ALA127
y	GLY130
y	LEU133
y	PRO134
y	HIS182
y	PHE183

---

site_id	AF9
Number of Residues	16
Details	binding site for residue HEM y 402

Chain	Residue
y	TRP31
y	GLY34
y	LEU37
y	PHE90
y	LEU94
y	HIS97
y	ARG100
y	SER106
y	TRP113
y	GLY116
y	VAL117
y	LEU119
y	HIS196
y	LEU200
y	SER205
y	ASN206

---

site_id	AG1
Number of Residues	12
Details	binding site for residue HEC z 301

Chain	Residue
z	VAL36
z	CYS37
z	SER39
z	CYS40
z	HIS41
z	ASN105
z	LEU113
z	ARG120
z	ILE158
z	GLY159
z	MET160
z	PRO163

---

site_id	AG2
Number of Residues	6
Details	binding site for residue UQ2 A2 201

Chain	Residue
A2	SER10
A2	ARG11
A2	LEU13
A2	GLU14
A2	GLY15
A2	ARG17

---

Functional Information from PROSITE/UniProt

site_id	PS00012
Number of Residues	16
Details	PHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM

Chain	Residue	Details
M	ASP39-MET54

---

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI

Chain	Residue	Details
M	ASP64-ILE76

---

site_id	PS00077
Number of Residues	56
Details	COX1_CUB Heme-copper oxidase catalytic subunit, copper B binding region signature. WFFGHPeVyililpgfgmishivtyysgkkepfgymgmvwammsigflgfivwa.HH

Chain	Residue	Details
C3	TRP236-HIS291

---

site_id	PS00078
Number of Residues	49
Details	COX2 CO II and nitrous oxide reductase dinuclear copper centers signature. VlHswavpslglktdaipgrlnqttlmssrpglyygq......CseiCgsnHsfM

Chain	Residue	Details
C1	VAL159-MET207

---

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryensnnlGtSHLLRLAsSlTT

Chain	Residue	Details
l	GLY54-THR77

---

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaVCP

Chain	Residue	Details
E	CYS113-PRO124
E	CYS152-PRO163

---

site_id	PS00535
Number of Residues	12
Details	COMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK

Chain	Residue	Details
B	LEU116-LYS127

---

site_id	PS00542
Number of Residues	22
Details	COMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREiwDMFgvffanHpdlRrIL

Chain	Residue	Details
C	GLU169-LEU190

---

site_id	PS00641
Number of Residues	18
Details	COMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC

Chain	Residue	Details
A	PRO61-CYS78

---

site_id	PS00642
Number of Residues	13
Details	COMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ

Chain	Residue	Details
A	CYS128-GLN140

---

site_id	PS00643
Number of Residues	11
Details	COMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF

Chain	Residue	Details
A	ARG175-PHE185

---

site_id	PS00644
Number of Residues	16
Details	COMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES

Chain	Residue	Details
8	GLY200-SER215

---

site_id	PS00645
Number of Residues	12
Details	COMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG

Chain	Residue	Details
8	GLU377-GLY388

---

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpIaDAIKLFiKE

Chain	Residue	Details
1	GLY44-GLU59

---

site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G

Chain	Residue	Details
1	PRO197-GLY210

---

site_id	PS00848
Number of Residues	23
Details	COX5B_1 Cytochrome c oxidase subunit Vb, zinc binding region signature. VIWfwlhkgeaqrCpsCGthYKL

Chain	Residue	Details
A5	VAL69-LEU91

---

site_id	PS01099
Number of Residues	19
Details	COMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP

Chain	Residue	Details
9	ASP166-PRO184

---

site_id	PS01150
Number of Residues	17
Details	COMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP

Chain	Residue	Details
D	GLY172-PRO188

---

site_id	PS01329
Number of Residues	18
Details	COX6A Cytochrome c oxidase subunit VIa signature. IRtKpFsWGDGnHTfFhN

Chain	Residue	Details
A6	ILE55-ASN72

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
8	GLY87
2	ASN274-MET294
2	PHE325-VAL345
6	LEU413-GLY433
6	LEU457-ILE477
6	MET482-LEU502
6	GLY582-PHE602
y	TYR347-PRO367
8	ARG199
2	SER67-MET87
2	MET96-PRO116
2	ILE122-LEU142
2	ILE145-GLY165
2	ILE178-PRO198
2	MET200-MET220
2	ILE239-GLY259

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:27509854, ECO:0007744|PDB:5LC5, ECO:0007744|PDB:5LDW, ECO:0007744|PDB:5LDX

Chain	Residue	Details
8	CYS379
8	CYS382
8	CYS385
8	CYS425
A2	LYS82
A2	LYS95

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q91YT0

Chain	Residue	Details
8	LYS81
B6	ASN47-GLU63
A2	LYS77
A2	LYS87

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q91YT0

Chain	Residue	Details
8	LYS104
A1	SER163
8	LYS375
p	CYS158
p	HIS161
p	SER163
A1	CYS139
A1	HIS141
A1	CYS158
A1	HIS161

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine => ECO:0000250|UniProtKB:Q91YT0

Chain	Residue	Details
8	ARG257
z	HIS41
C1	GLU198
C1	CYS200
C1	HIS204
C1	MET207

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	BINDING: axial binding residue => ECO:0000269|PubMed:9651245, ECO:0007744|PDB:1BE3

Chain	Residue	Details
o	MET160
z	MET160
C3	VAL287-ASP298

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:P19783

Chain	Residue	Details
A7	LYS45

---

site_id	SWS_FT_FI8
Number of Residues	32
Details	TRANSMEM: Helical; Name=VI => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A9	GLY191-LEU223

---

site_id	SWS_FT_FI9
Number of Residues	23
Details	TRANSMEM: Helical; Name=VII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
A9	PHE233-ILE256

---

site_id	SWS_FT_FI10
Number of Residues	16
Details	TRANSMEM: Helical; Name=VII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	TYR270-ILE286

---

site_id	SWS_FT_FI11
Number of Residues	28
Details	TRANSMEM: Helical; Name=VIII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	VAL299-LEU327

---

site_id	SWS_FT_FI12
Number of Residues	7
Details	TOPO_DOM: Mitochondrial matrix => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	HIS328-SER335

---

site_id	SWS_FT_FI13
Number of Residues	21
Details	TRANSMEM: Helical; Name=IX => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	PRO336-VAL357

---

site_id	SWS_FT_FI14
Number of Residues	24
Details	TOPO_DOM: Mitochondrial intermembrane => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	LEU358-THR370
C3	SER434-ALA446

---

site_id	SWS_FT_FI15
Number of Residues	29
Details	TRANSMEM: Helical; Name=X => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	TYR371-PHE400

---

site_id	SWS_FT_FI16
Number of Residues	26
Details	TRANSMEM: Helical; Name=XI => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	ASP407-LEU433

---

site_id	SWS_FT_FI17
Number of Residues	31
Details	TRANSMEM: Helical; Name=XII => ECO:0000269|PubMed:27605664

Chain	Residue	Details
C3	TYR447-SER478

---

site_id	SWS_FT_FI18
Number of Residues	3
Details	BINDING: BINDING => ECO:0000269|PubMed:27605664, ECO:0000305|PubMed:23537388

Chain	Residue	Details
C3	GLU40
C3	GLY45
C3	SER441

---

site_id	SWS_FT_FI19
Number of Residues	3
Details	BINDING: axial binding residue => ECO:0000269|PubMed:20385840, ECO:0000269|PubMed:8638158

Chain	Residue	Details
C3	HIS61
C3	HIS376
C3	HIS378

---

site_id	SWS_FT_FI20
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:20385840, ECO:0000269|PubMed:8638158

Chain	Residue	Details
C3	HIS240
C3	HIS290
C3	HIS291
C3	HIS368
C3	ASP369

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	BINDING: BINDING => ECO:0000305

Chain	Residue	Details
C3	TYR244

---

site_id	SWS_FT_FI22
Number of Residues	1
Details	MOD_RES: N-formylmethionine => ECO:0000269|PubMed:2165784

Chain	Residue	Details
C3	MET1

---

site_id	SWS_FT_FI23
Number of Residues	2
Details	CROSSLNK: 1'-histidyl-3'-tyrosine (His-Tyr) => ECO:0000269|PubMed:10338009

Chain	Residue	Details
C3	HIS240
C3	TYR244

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	14
Details	M-CSA 124

Chain	Residue	Details
C3	HIS61	metal ligand
C3	HIS290	metal ligand
C3	HIS291	metal ligand, proton acceptor, proton donor
C3	THR316	proton acceptor, proton donor, proton relay
C3	LYS319	proton acceptor, proton donor, proton relay
C3	ARG438	proton acceptor, proton donor, proton relay
C3	ASP91	proton acceptor, proton donor, proton relay
C3	TRP126	proton acceptor, proton donor, proton relay
C3	SER156	proton acceptor, proton donor, proton relay
C3	SER157	proton acceptor, proton donor, proton relay
C3	HIS240	covalently attached, electrostatic stabiliser, metal ligand, radical stabiliser
C3	GLU242	proton acceptor, proton donor, proton relay
C3	TYR244	covalently attached, hydrogen radical donor, proton acceptor, proton donor, proton relay, single electron acceptor
C3	SER255	proton acceptor, proton donor, proton relay

---