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7DCI

Crystal structure of HSF2 DNA-binding domain in complex with 2-site HSE DNA in the head-to-head orientation

Functional Information from GO Data
ChainGOidnamespacecontents
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
A0043565molecular_functionsequence-specific DNA binding
Functional Information from PROSITE/UniProt
site_idPS00434
Number of Residues25
DetailsHSF_DOMAIN HSF-type DNA-binding domain signature. LpkyFKHnNmASFVRQLNmYgFRKV
ChainResidueDetails
ALEU49-VAL73

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS82

238268

PDB entries from 2025-07-02

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