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7D6R

Crystal structure of the Stx2a complexed with MMA betaAla peptide

Functional Information from GO Data
ChainGOidnamespacecontents
A0016787molecular_functionhydrolase activity
A0017148biological_processnegative regulation of translation
A0030598molecular_functionrRNA N-glycosylase activity
A0035821biological_processmodulation of process of another organism
A0090729molecular_functiontoxin activity
B0005576cellular_componentextracellular region
B0019836biological_processsymbiont-mediated hemolysis of host erythrocyte
B0035821biological_processmodulation of process of another organism
B0090729molecular_functiontoxin activity
C0005576cellular_componentextracellular region
C0019836biological_processsymbiont-mediated hemolysis of host erythrocyte
C0035821biological_processmodulation of process of another organism
C0090729molecular_functiontoxin activity
D0005576cellular_componentextracellular region
D0019836biological_processsymbiont-mediated hemolysis of host erythrocyte
D0035821biological_processmodulation of process of another organism
D0090729molecular_functiontoxin activity
E0005576cellular_componentextracellular region
E0019836biological_processsymbiont-mediated hemolysis of host erythrocyte
E0035821biological_processmodulation of process of another organism
E0090729molecular_functiontoxin activity
F0005576cellular_componentextracellular region
F0019836biological_processsymbiont-mediated hemolysis of host erythrocyte
F0035821biological_processmodulation of process of another organism
F0090729molecular_functiontoxin activity
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue 1PS B 101
ChainResidue
BASP16
BTHR18
BTRP29
BHOH216

site_idAC2
Number of Residues5
Detailsbinding site for residue 1PS C 101
ChainResidue
CASP16
CTHR18
CTRP29
CHOH220
DSER58

site_idAC3
Number of Residues7
Detailsbinding site for residue 1PS D 101
ChainResidue
CSER58
DASN14
DASP16
DTHR18
DTRP29
DHOH201
DHOH219

site_idAC4
Number of Residues4
Detailsbinding site for residue 1PS F 101
ChainResidue
FASP16
FTHR18
FTRP29
FHOH215

site_idAC5
Number of Residues6
Detailsbinding site for Di-peptide ALA G 10 and NH2 G 11
ChainResidue
AVAL78
ASER112
ATYR114
AVAL162
GARG9
GHOH103

Functional Information from PROSITE/UniProt
site_idPS00275
Number of Residues17
DetailsSHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. VtVTaEALRFRqIQreF
ChainResidueDetails
AVAL162-PHE178

246031

PDB entries from 2025-12-10

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