7D6Q
Crystal structure of the Stx2a
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017148 | biological_process | negative regulation of translation |
| A | 0030598 | molecular_function | rRNA N-glycosylase activity |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0090729 | molecular_function | toxin activity |
| B | 0005576 | cellular_component | extracellular region |
| B | 0019836 | biological_process | hemolysis by symbiont of host erythrocytes |
| C | 0005576 | cellular_component | extracellular region |
| C | 0019836 | biological_process | hemolysis by symbiont of host erythrocytes |
| D | 0005576 | cellular_component | extracellular region |
| D | 0019836 | biological_process | hemolysis by symbiont of host erythrocytes |
| E | 0005576 | cellular_component | extracellular region |
| E | 0019836 | biological_process | hemolysis by symbiont of host erythrocytes |
| F | 0005576 | cellular_component | extracellular region |
| F | 0019836 | biological_process | hemolysis by symbiont of host erythrocytes |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue 1PS B 101 |
| Chain | Residue |
| B | ASN14 |
| B | ASP16 |
| B | THR18 |
| B | TRP29 |
| B | HOH211 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue 1PS C 101 |
| Chain | Residue |
| C | HOH205 |
| C | HOH224 |
| D | SER58 |
| C | GLU15 |
| C | ASP16 |
| C | THR18 |
| C | TRP29 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue 1PS D 101 |
| Chain | Residue |
| C | SER58 |
| D | ASN14 |
| D | GLU15 |
| D | ASP16 |
| D | THR18 |
| D | TRP29 |
| D | HOH202 |
| D | HOH222 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue 1PS F 101 |
| Chain | Residue |
| F | ASN14 |
| F | ASP16 |
| F | THR18 |
| F | TRP29 |
| F | HOH208 |
Functional Information from PROSITE/UniProt
| site_id | PS00275 |
| Number of Residues | 17 |
| Details | SHIGA_RICIN Shiga/ricin ribosomal inactivating toxins active site signature. VtVTaEALRFRqIQreF |
| Chain | Residue | Details |
| A | VAL162-PHE178 |
