7D4U
ATP complex with double mutant cyclic trinucleotide synthase CdnD
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0009117 | biological_process | nucleotide metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051607 | biological_process | defense response to virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue ATP A 401 |
| Chain | Residue |
| A | GLY52 |
| A | ATP402 |
| A | HOH513 |
| A | HOH527 |
| A | HOH534 |
| A | HOH539 |
| A | HOH552 |
| A | SER53 |
| A | ARG56 |
| A | LYS71 |
| A | GLN210 |
| A | GLY249 |
| A | TYR250 |
| A | ASP296 |
| A | VAL304 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue ATP A 402 |
| Chain | Residue |
| A | GLN51 |
| A | ARG109 |
| A | LEU194 |
| A | ASP196 |
| A | ARG197 |
| A | ARG204 |
| A | THR205 |
| A | HIS302 |
| A | ARG307 |
| A | ATP401 |
| A | HOH501 |
| A | HOH502 |
| A | HOH522 |
| A | HOH540 |
| A | HOH543 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"33836064","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33836064","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"36755092","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"7D4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LJL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TO3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TQD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33836064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36755092","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7D4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LJL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TO3","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33836064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"36755092","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7D4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LJL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TO3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TQD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33836064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7D4S","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7D4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LJL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TO3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TQD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33836064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7D4J","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7D4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LJL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TO3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TQD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33836064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7D4S","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7D4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LJL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LJL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33836064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7D4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LJL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TO3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TQD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"7TO3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TQD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7LJL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TO3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7TQD","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33836064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7D4J","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7D4S","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"7D4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LJL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33836064","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7D4O","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7LJL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for GTP discrimination","evidences":[{"source":"PubMed","id":"34077735","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
