7D42
Structural basis of tropifexor as a potent and selective agonist for farnesoid X receptor
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0007744|PDB:6HL1 |
| Chain | Residue | Details |
| A | ARG331 | |
| A | TYR361 | |
| A | TYR369 | |
| A | HIS447 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by PKC/PRKCZ => ECO:0000305|PubMed:18668687 |
| Chain | Residue | Details |
| A | THR442 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000305|PubMed:23546875 |
| Chain | Residue | Details |
| A | LYS275 |
