7D0R
Crystal structure of human HBO1-BRPF2 in complex with crotonoyl-coenzyme A
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 25 |
| Details | ZN_FING: C2HC MYST-type => ECO:0000255|PROSITE-ProRule:PRU01063 |
| Chain | Residue | Details |
| A | LEU365-TRP390 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000305|PubMed:31827282 |
| Chain | Residue | Details |
| A | GLU508 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28334966, ECO:0000269|PubMed:31827282, ECO:0007744|PDB:5GK9, ECO:0007744|PDB:6MAJ, ECO:0007744|PDB:6MAK |
| Chain | Residue | Details |
| A | CYS368 | |
| A | CYS371 | |
| A | HIS384 | |
| A | CYS388 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:28334966, ECO:0000269|PubMed:31827282, ECO:0007744|PDB:5GK9, ECO:0007744|PDB:6MAK |
| Chain | Residue | Details |
| A | SER512 | |
| A | SER521 | |
| A | ILE475 | |
| A | ARG483 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-acetyllysine; by autocatalysis => ECO:0000250|UniProtKB:Q9H7Z6 |
| Chain | Residue | Details |
| A | ALY432 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER506 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23319590 |
| Chain | Residue | Details |
| A | LYS338 |
