7D0I

Cryo-EM structure of Schizosaccharomyces pombe Atg9

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0000045	biological_process	autophagosome assembly
B	0000139	cellular_component	Golgi membrane
B	0000329	cellular_component	fungal-type vacuole membrane
B	0000407	cellular_component	phagophore assembly site
B	0000423	biological_process	mitophagy
B	0005776	cellular_component	autophagosome
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005794	cellular_component	Golgi apparatus
B	0006869	biological_process	lipid transport
B	0006914	biological_process	autophagy
B	0016020	cellular_component	membrane
B	0016236	biological_process	macroautophagy
B	0017121	biological_process	plasma membrane phospholipid scrambling
B	0017128	molecular_function	phospholipid scramblase activity
B	0030659	cellular_component	cytoplasmic vesicle membrane
B	0031410	cellular_component	cytoplasmic vesicle
B	0034045	cellular_component	phagophore assembly site membrane
B	0034497	biological_process	protein localization to phagophore assembly site
B	0034727	biological_process	piecemeal microautophagy of the nucleus
B	0061709	biological_process	reticulophagy
D	0000045	biological_process	autophagosome assembly
D	0000139	cellular_component	Golgi membrane
D	0000329	cellular_component	fungal-type vacuole membrane
D	0000407	cellular_component	phagophore assembly site
D	0000423	biological_process	mitophagy
D	0005776	cellular_component	autophagosome
D	0005783	cellular_component	endoplasmic reticulum
D	0005789	cellular_component	endoplasmic reticulum membrane
D	0005794	cellular_component	Golgi apparatus
D	0006869	biological_process	lipid transport
D	0006914	biological_process	autophagy
D	0016020	cellular_component	membrane
D	0016236	biological_process	macroautophagy
D	0017121	biological_process	plasma membrane phospholipid scrambling
D	0017128	molecular_function	phospholipid scramblase activity
D	0030659	cellular_component	cytoplasmic vesicle membrane
D	0031410	cellular_component	cytoplasmic vesicle
D	0034045	cellular_component	phagophore assembly site membrane
D	0034497	biological_process	protein localization to phagophore assembly site
D	0034727	biological_process	piecemeal microautophagy of the nucleus
D	0061709	biological_process	reticulophagy
F	0000045	biological_process	autophagosome assembly
F	0000139	cellular_component	Golgi membrane
F	0000329	cellular_component	fungal-type vacuole membrane
F	0000407	cellular_component	phagophore assembly site
F	0000423	biological_process	mitophagy
F	0005776	cellular_component	autophagosome
F	0005783	cellular_component	endoplasmic reticulum
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0005794	cellular_component	Golgi apparatus
F	0006869	biological_process	lipid transport
F	0006914	biological_process	autophagy
F	0016020	cellular_component	membrane
F	0016236	biological_process	macroautophagy
F	0017121	biological_process	plasma membrane phospholipid scrambling
F	0017128	molecular_function	phospholipid scramblase activity
F	0030659	cellular_component	cytoplasmic vesicle membrane
F	0031410	cellular_component	cytoplasmic vesicle
F	0034045	cellular_component	phagophore assembly site membrane
F	0034497	biological_process	protein localization to phagophore assembly site
F	0034727	biological_process	piecemeal microautophagy of the nucleus
F	0061709	biological_process	reticulophagy
H	0000045	biological_process	autophagosome assembly
H	0000139	cellular_component	Golgi membrane
H	0000329	cellular_component	fungal-type vacuole membrane
H	0000407	cellular_component	phagophore assembly site
H	0000423	biological_process	mitophagy
H	0005776	cellular_component	autophagosome
H	0005783	cellular_component	endoplasmic reticulum
H	0005789	cellular_component	endoplasmic reticulum membrane
H	0005794	cellular_component	Golgi apparatus
H	0006869	biological_process	lipid transport
H	0006914	biological_process	autophagy
H	0016020	cellular_component	membrane
H	0016236	biological_process	macroautophagy
H	0017121	biological_process	plasma membrane phospholipid scrambling
H	0017128	molecular_function	phospholipid scramblase activity
H	0030659	cellular_component	cytoplasmic vesicle membrane
H	0031410	cellular_component	cytoplasmic vesicle
H	0034045	cellular_component	phagophore assembly site membrane
H	0034497	biological_process	protein localization to phagophore assembly site
H	0034727	biological_process	piecemeal microautophagy of the nucleus
H	0061709	biological_process	reticulophagy
J	0000045	biological_process	autophagosome assembly
J	0000139	cellular_component	Golgi membrane
J	0000329	cellular_component	fungal-type vacuole membrane
J	0000407	cellular_component	phagophore assembly site
J	0000423	biological_process	mitophagy
J	0005776	cellular_component	autophagosome
J	0005783	cellular_component	endoplasmic reticulum
J	0005789	cellular_component	endoplasmic reticulum membrane
J	0005794	cellular_component	Golgi apparatus
J	0006869	biological_process	lipid transport
J	0006914	biological_process	autophagy
J	0016020	cellular_component	membrane
J	0016236	biological_process	macroautophagy
J	0017121	biological_process	plasma membrane phospholipid scrambling
J	0017128	molecular_function	phospholipid scramblase activity
J	0030659	cellular_component	cytoplasmic vesicle membrane
J	0031410	cellular_component	cytoplasmic vesicle
J	0034045	cellular_component	phagophore assembly site membrane
J	0034497	biological_process	protein localization to phagophore assembly site
J	0034727	biological_process	piecemeal microautophagy of the nucleus
J	0061709	biological_process	reticulophagy
L	0000045	biological_process	autophagosome assembly
L	0000139	cellular_component	Golgi membrane
L	0000329	cellular_component	fungal-type vacuole membrane
L	0000407	cellular_component	phagophore assembly site
L	0000423	biological_process	mitophagy
L	0005776	cellular_component	autophagosome
L	0005783	cellular_component	endoplasmic reticulum
L	0005789	cellular_component	endoplasmic reticulum membrane
L	0005794	cellular_component	Golgi apparatus
L	0006869	biological_process	lipid transport
L	0006914	biological_process	autophagy
L	0016020	cellular_component	membrane
L	0016236	biological_process	macroautophagy
L	0017121	biological_process	plasma membrane phospholipid scrambling
L	0017128	molecular_function	phospholipid scramblase activity
L	0030659	cellular_component	cytoplasmic vesicle membrane
L	0031410	cellular_component	cytoplasmic vesicle
L	0034045	cellular_component	phagophore assembly site membrane
L	0034497	biological_process	protein localization to phagophore assembly site
L	0034727	biological_process	piecemeal microautophagy of the nucleus
L	0061709	biological_process	reticulophagy

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue LMN B 801

Chain	Residue
B	PHE264
B	GLN472
B	LMN802
B	ASP347
B	GLU376
B	TRP377
B	ASN378
B	ASN380
B	PHE425
B	VAL429
B	TRP463

---

site_id	AC2
Number of Residues	12
Details	binding site for residue LMN B 802

Chain	Residue
B	THR195
B	GLN209
B	PHE261
B	LEU268
B	TYR271
B	HIS373
B	TRP377
B	TYR432
B	ASN437
B	LEU607
B	GLU610
B	LMN801

---

site_id	AC3
Number of Residues	12
Details	binding site for residue LMN D 801

Chain	Residue
D	PHE264
D	ASP347
D	GLU376
D	TRP377
D	ASN378
D	ASN380
D	PHE425
D	VAL429
D	TRP463
D	GLN472
D	ASP476
D	LMN802

---

site_id	AC4
Number of Residues	12
Details	binding site for residue LMN D 802

Chain	Residue
D	THR195
D	GLN209
D	PHE261
D	LEU268
D	TYR271
D	HIS373
D	TRP377
D	TYR432
D	ASN437
D	LEU607
D	GLU610
D	LMN801

---

site_id	AC5
Number of Residues	11
Details	binding site for residue LMN F 801

Chain	Residue
F	ASP347
F	GLU376
F	TRP377
F	ASN378
F	ASN380
F	VAL429
F	TRP463
F	ARG466
F	GLN472
F	ASP476
F	LMN802

---

site_id	AC6
Number of Residues	9
Details	binding site for residue LMN F 802

Chain	Residue
F	THR195
F	GLN209
F	TYR271
F	HIS373
F	TRP377
F	TYR432
F	ARG440
F	GLU610
F	LMN801

---

site_id	AC7
Number of Residues	11
Details	binding site for residue LMN H 801

Chain	Residue
H	PHE264
H	ASP347
H	GLU376
H	TRP377
H	ASN378
H	ASN380
H	PHE425
H	VAL429
H	TRP463
H	GLN472
H	LMN802

---

site_id	AC8
Number of Residues	11
Details	binding site for residue LMN H 802

Chain	Residue
H	THR195
H	GLN209
H	PHE261
H	TYR271
H	HIS373
H	TRP377
H	TYR432
H	ASN437
H	LEU607
H	GLU610
H	LMN801

---

site_id	AC9
Number of Residues	12
Details	binding site for residue LMN J 801

Chain	Residue
J	ASP476
J	LMN802
J	PHE264
J	ASP347
J	GLU376
J	TRP377
J	ASN378
J	ASN380
J	TRP381
J	TRP463
J	ARG466
J	GLN472

---

site_id	AD1
Number of Residues	10
Details	binding site for residue LMN J 802

Chain	Residue
J	THR195
J	GLN209
J	TYR271
J	HIS373
J	TRP377
J	TYR432
J	ASN437
J	LEU607
J	GLU610
J	LMN801

---

site_id	AD2
Number of Residues	11
Details	binding site for residue LMN L 801

Chain	Residue
L	PHE264
L	GLU376
L	TRP377
L	ASN378
L	ASN380
L	ASN422
L	PHE425
L	VAL429
L	TRP463
L	GLN472
L	LMN802

---

site_id	AD3
Number of Residues	12
Details	binding site for residue LMN L 802

Chain	Residue
L	GLN209
L	PHE261
L	LEU268
L	TYR271
L	HIS373
L	TRP377
L	TYR432
L	LEU433
L	ASN437
L	LEU607
L	GLU610
L	LMN801

---

Functional Information from PROSITE/UniProt

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. RnPNSRkR

Chain	Residue	Details
B	ARG399-ARG406

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	462
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"33106658","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7D0I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	144
Details	Intramembrane: {"evidences":[{"source":"PubMed","id":"33106658","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7D0I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	576
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	120
Details	Intramembrane: {"evidences":[{"source":"PubMed","id":"33106658","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---