7CZ9
Crystal structure of multidrug efflux transporter OqxB from Klebsiella pneumoniae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0015562 | molecular_function | efflux transmembrane transporter activity |
| A | 0016020 | cellular_component | membrane |
| A | 0022857 | molecular_function | transmembrane transporter activity |
| A | 0042908 | biological_process | xenobiotic transport |
| A | 0042910 | molecular_function | xenobiotic transmembrane transporter activity |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0015562 | molecular_function | efflux transmembrane transporter activity |
| B | 0016020 | cellular_component | membrane |
| B | 0022857 | molecular_function | transmembrane transporter activity |
| B | 0042908 | biological_process | xenobiotic transport |
| B | 0042910 | molecular_function | xenobiotic transmembrane transporter activity |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0015562 | molecular_function | efflux transmembrane transporter activity |
| C | 0016020 | cellular_component | membrane |
| C | 0022857 | molecular_function | transmembrane transporter activity |
| C | 0042908 | biological_process | xenobiotic transport |
| C | 0042910 | molecular_function | xenobiotic transmembrane transporter activity |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0015562 | molecular_function | efflux transmembrane transporter activity |
| D | 0016020 | cellular_component | membrane |
| D | 0022857 | molecular_function | transmembrane transporter activity |
| D | 0042908 | biological_process | xenobiotic transport |
| D | 0042910 | molecular_function | xenobiotic transmembrane transporter activity |
| D | 0055085 | biological_process | transmembrane transport |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0015562 | molecular_function | efflux transmembrane transporter activity |
| E | 0016020 | cellular_component | membrane |
| E | 0022857 | molecular_function | transmembrane transporter activity |
| E | 0042908 | biological_process | xenobiotic transport |
| E | 0042910 | molecular_function | xenobiotic transmembrane transporter activity |
| E | 0055085 | biological_process | transmembrane transport |
| F | 0005886 | cellular_component | plasma membrane |
| F | 0015562 | molecular_function | efflux transmembrane transporter activity |
| F | 0016020 | cellular_component | membrane |
| F | 0022857 | molecular_function | transmembrane transporter activity |
| F | 0042908 | biological_process | xenobiotic transport |
| F | 0042910 | molecular_function | xenobiotic transmembrane transporter activity |
| F | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue LMT A 1101 |
| Chain | Residue |
| A | LEU388 |
| A | GLY390 |
| A | LMT1109 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue LMT A 1102 |
| Chain | Residue |
| A | GLU957 |
| A | HOH1248 |
| A | HOH1312 |
| C | ARG10 |
| C | PHE13 |
| C | LMT1104 |
| A | MET1 |
| A | GLY442 |
| A | ALA896 |
| A | LEU897 |
| A | GLU899 |
| A | ARG956 |
| site_id | AC3 |
| Number of Residues | 12 |
| Details | binding site for residue LMT A 1103 |
| Chain | Residue |
| A | ASP9 |
| A | ARG10 |
| A | PRO11 |
| A | ILE12 |
| A | ALA15 |
| A | ILE19 |
| A | PHE22 |
| A | ILE373 |
| A | LEU497 |
| B | GLU899 |
| B | TRP901 |
| B | PTY1111 |
| site_id | AC4 |
| Number of Residues | 21 |
| Details | binding site for residue LMT A 1104 |
| Chain | Residue |
| A | LYS81 |
| A | TYR579 |
| A | VAL616 |
| A | ALA623 |
| A | LEU624 |
| A | GLN625 |
| A | PHE626 |
| A | PHE636 |
| A | GLY638 |
| A | PRO674 |
| A | ILE676 |
| A | LEU677 |
| A | GLY678 |
| A | LEU679 |
| A | GLY680 |
| A | ASP867 |
| A | LMT1105 |
| A | HOH1226 |
| A | HOH1354 |
| A | HOH1469 |
| A | HOH1635 |
| site_id | AC5 |
| Number of Residues | 15 |
| Details | binding site for residue LMT A 1105 |
| Chain | Residue |
| A | GLN46 |
| A | ARG48 |
| A | GLN134 |
| A | ARG157 |
| A | GLN176 |
| A | GLN178 |
| A | ILE179 |
| A | PHE180 |
| A | PHE295 |
| A | PHE626 |
| A | LMT1104 |
| A | HOH1356 |
| A | HOH1400 |
| A | HOH1415 |
| A | HOH1534 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | binding site for residue LMT A 1106 |
| Chain | Residue |
| A | ILE29 |
| A | ASN301 |
| A | ASP304 |
| A | ASN307 |
| A | ARG337 |
| A | ILE340 |
| A | LEU348 |
| A | HOH1289 |
| A | HOH1337 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue LMT A 1107 |
| Chain | Residue |
| A | MET458 |
| A | PHE564 |
| A | ASN877 |
| A | PHE883 |
| A | ASN929 |
| A | GLN934 |
| A | VAL938 |
| A | LMT1108 |
| A | HOH1319 |
| site_id | AC8 |
| Number of Residues | 14 |
| Details | binding site for residue LMT A 1108 |
| Chain | Residue |
| A | PHE455 |
| A | TYR469 |
| A | ALA473 |
| A | ILE476 |
| A | GLY570 |
| A | PHE571 |
| A | SER842 |
| A | GLN872 |
| A | GLN875 |
| A | ASN877 |
| A | PHE883 |
| A | GLN934 |
| A | VAL935 |
| A | LMT1107 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue LMT A 1109 |
| Chain | Residue |
| A | LYS470 |
| A | GLN471 |
| A | LMT1101 |
| A | HOH1212 |
| A | PRO38 |
| A | ASP39 |
| A | GLY390 |
| A | SER392 |
| site_id | AD1 |
| Number of Residues | 11 |
| Details | binding site for residue LMT A 1110 |
| Chain | Residue |
| A | ARG170 |
| A | ARG771 |
| A | GOL1117 |
| B | GLU68 |
| B | ASN72 |
| B | MET78 |
| B | MET80 |
| B | ARG97 |
| B | ARG822 |
| B | ASN824 |
| B | GLY825 |
| site_id | AD2 |
| Number of Residues | 16 |
| Details | binding site for residue LMT A 1111 |
| Chain | Residue |
| A | GLU36 |
| A | TYR37 |
| A | PHE335 |
| A | SER339 |
| A | ALA342 |
| A | THR395 |
| A | VAL402 |
| A | GLY406 |
| A | GLN575 |
| A | LYS577 |
| A | ALA986 |
| A | LEU994 |
| A | GLY1001 |
| A | ARG1005 |
| A | THR1008 |
| A | HOH1245 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue PTY A 1112 |
| Chain | Residue |
| A | LEU888 |
| A | TRP901 |
| A | LEU1037 |
| A | ARG1040 |
| C | ILE19 |
| C | LMT1104 |
| site_id | AD4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 1113 |
| Chain | Residue |
| A | ARG310 |
| A | ALA314 |
| A | HOH1206 |
| D | PRO321 |
| D | GLU322 |
| D | HOH1464 |
| site_id | AD5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 1114 |
| Chain | Residue |
| A | PRO172 |
| A | GLY173 |
| A | ALA300 |
| A | ASN301 |
| A | ASP304 |
| A | LEU305 |
| A | HOH1223 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 1115 |
| Chain | Residue |
| A | SER702 |
| A | ASN705 |
| A | ALA706 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 1116 |
| Chain | Residue |
| A | VAL584 |
| A | ASN622 |
| A | ALA623 |
| A | THR632 |
| A | GLY633 |
| A | THR634 |
| A | PHE669 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 1117 |
| Chain | Residue |
| A | ASP166 |
| A | ARG170 |
| A | ARG771 |
| A | LMT1110 |
| A | HOH1476 |
| B | GLY825 |
| B | TYR826 |
| site_id | AD9 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 1118 |
| Chain | Residue |
| A | ALA118 |
| A | ARG119 |
| A | LEU120 |
| A | HOH1234 |
| C | GLN216 |
| C | ARG242 |
| C | ASN764 |
| C | ASP765 |
| C | HOH1418 |
| site_id | AE1 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 1119 |
| Chain | Residue |
| A | SER182 |
| A | GLY183 |
| A | GLU184 |
| A | SER277 |
| A | ARG774 |
| A | HOH1204 |
| site_id | AE2 |
| Number of Residues | 9 |
| Details | binding site for residue GOL A 1120 |
| Chain | Residue |
| A | GLN216 |
| A | ARG242 |
| A | TYR762 |
| A | ASN764 |
| A | ASP765 |
| A | HOH1203 |
| A | HOH1318 |
| B | ARG119 |
| B | LEU120 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 1121 |
| Chain | Residue |
| A | ALA198 |
| A | ARG199 |
| A | LYS255 |
| A | ALA257 |
| A | GLN258 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue LMT B 1101 |
| Chain | Residue |
| B | LEU31 |
| B | PRO33 |
| B | TYR387 |
| B | GLY390 |
| site_id | AE5 |
| Number of Residues | 23 |
| Details | binding site for residue LMT B 1102 |
| Chain | Residue |
| B | LYS81 |
| B | PRO329 |
| B | TYR330 |
| B | TYR579 |
| B | VAL616 |
| B | ALA623 |
| B | LEU624 |
| B | GLN625 |
| B | PHE626 |
| B | PHE636 |
| B | GLY638 |
| B | PRO674 |
| B | ILE676 |
| B | LEU677 |
| B | GLY678 |
| B | LEU679 |
| B | GLY680 |
| B | LMT1105 |
| B | HOH1228 |
| B | HOH1241 |
| B | HOH1315 |
| B | HOH1467 |
| B | HOH1522 |
| site_id | AE6 |
| Number of Residues | 17 |
| Details | binding site for residue LMT B 1103 |
| Chain | Residue |
| B | GLU36 |
| B | TYR37 |
| B | PHE335 |
| B | SER339 |
| B | ALA342 |
| B | THR395 |
| B | VAL402 |
| B | GLN575 |
| B | LYS577 |
| B | ALA986 |
| B | PHE987 |
| B | LEU994 |
| B | GLY1001 |
| B | ARG1005 |
| B | THR1008 |
| B | HOH1213 |
| B | HOH1226 |
| site_id | AE7 |
| Number of Residues | 11 |
| Details | binding site for residue LMT B 1104 |
| Chain | Residue |
| A | ARG10 |
| A | VAL16 |
| B | MET1 |
| B | PHE3 |
| B | GLY442 |
| B | ALA896 |
| B | LEU897 |
| B | GLU899 |
| B | ARG956 |
| B | GLU957 |
| B | HOH1382 |
| site_id | AE8 |
| Number of Residues | 14 |
| Details | binding site for residue LMT B 1105 |
| Chain | Residue |
| B | GLN46 |
| B | GLN134 |
| B | ARG157 |
| B | GLN176 |
| B | GLN178 |
| B | ILE179 |
| B | PHE180 |
| B | LEU280 |
| B | PHE626 |
| B | ASN628 |
| B | LMT1102 |
| B | HOH1320 |
| B | HOH1399 |
| B | HOH1532 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue LMT B 1106 |
| Chain | Residue |
| B | ASP304 |
| B | ASN307 |
| B | LEU347 |
| B | VAL380 |
| site_id | AF1 |
| Number of Residues | 8 |
| Details | binding site for residue LMT B 1107 |
| Chain | Residue |
| B | VAL454 |
| B | MET458 |
| B | PHE564 |
| B | PHE883 |
| B | MET915 |
| B | ASN929 |
| B | GLN934 |
| B | LMT1108 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue LMT B 1108 |
| Chain | Residue |
| B | MET458 |
| B | TYR469 |
| B | ASN877 |
| B | PHE883 |
| B | LMT1107 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue LMT B 1109 |
| Chain | Residue |
| B | LEU389 |
| B | GLY390 |
| B | LYS470 |
| site_id | AF4 |
| Number of Residues | 1 |
| Details | binding site for residue LMT B 1110 |
| Chain | Residue |
| B | VAL456 |
| site_id | AF5 |
| Number of Residues | 6 |
| Details | binding site for residue PTY B 1111 |
| Chain | Residue |
| A | LMT1103 |
| B | PHE891 |
| B | TRP901 |
| B | ARG1035 |
| B | VAL1038 |
| B | THR1039 |
| site_id | AF6 |
| Number of Residues | 3 |
| Details | binding site for residue PTY B 1112 |
| Chain | Residue |
| B | PRO30 |
| B | LEU31 |
| C | PHE460 |
| site_id | AF7 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 1113 |
| Chain | Residue |
| B | GLN435 |
| B | ARG438 |
| B | GLU957 |
| B | GLN961 |
| site_id | AF8 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 1114 |
| Chain | Residue |
| B | LYS963 |
| B | GLU967 |
| D | LYS541 |
| site_id | AF9 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 1115 |
| Chain | Residue |
| A | GLU439 |
| A | PHE954 |
| A | GLU957 |
| A | LEU958 |
| A | LEU975 |
| B | GLN258 |
| B | ASP259 |
| site_id | AG1 |
| Number of Residues | 7 |
| Details | binding site for residue LMT C 1101 |
| Chain | Residue |
| C | VAL454 |
| C | PHE564 |
| C | LYS565 |
| C | PHE883 |
| C | ASN929 |
| C | GLN934 |
| C | LMT1111 |
| site_id | AG2 |
| Number of Residues | 11 |
| Details | binding site for residue LMT C 1102 |
| Chain | Residue |
| B | ARG10 |
| C | MET1 |
| C | PHE3 |
| C | GLY442 |
| C | VAL893 |
| C | ALA896 |
| C | LEU897 |
| C | GLU899 |
| C | ARG956 |
| C | GLU957 |
| C | HOH1236 |
| site_id | AG3 |
| Number of Residues | 10 |
| Details | binding site for residue LMT C 1103 |
| Chain | Residue |
| B | ASP9 |
| B | ARG10 |
| B | PRO11 |
| B | ILE12 |
| B | ALA15 |
| B | PHE22 |
| B | VAL377 |
| B | LEU497 |
| C | GLU899 |
| C | TRP901 |
| site_id | AG4 |
| Number of Residues | 12 |
| Details | binding site for residue LMT C 1104 |
| Chain | Residue |
| A | GLU899 |
| A | TRP901 |
| A | LMT1102 |
| A | PTY1112 |
| A | HOH1342 |
| C | ARG10 |
| C | PRO11 |
| C | ILE12 |
| C | ILE19 |
| C | VAL377 |
| C | LEU497 |
| C | HOH1213 |
| site_id | AG5 |
| Number of Residues | 15 |
| Details | binding site for residue LMT C 1105 |
| Chain | Residue |
| C | GLU36 |
| C | TYR37 |
| C | PHE335 |
| C | ASP338 |
| C | SER339 |
| C | ALA342 |
| C | THR395 |
| C | PHE399 |
| C | GLN575 |
| C | LYS577 |
| C | ALA986 |
| C | LEU994 |
| C | GLY1001 |
| C | ARG1005 |
| C | HOH1246 |
| site_id | AG6 |
| Number of Residues | 8 |
| Details | binding site for residue LMT C 1106 |
| Chain | Residue |
| C | PRO38 |
| C | ASP39 |
| C | LEU389 |
| C | GLY390 |
| C | LYS470 |
| C | GLN471 |
| C | HOH1280 |
| C | HOH1389 |
| site_id | AG7 |
| Number of Residues | 21 |
| Details | binding site for residue LMT C 1107 |
| Chain | Residue |
| C | LYS81 |
| C | TYR330 |
| C | TYR579 |
| C | ALA623 |
| C | LEU624 |
| C | GLN625 |
| C | PHE626 |
| C | PHE636 |
| C | GLY638 |
| C | PRO674 |
| C | ILE676 |
| C | LEU677 |
| C | GLY678 |
| C | LEU679 |
| C | GLY680 |
| C | HOH1201 |
| C | HOH1206 |
| C | HOH1251 |
| C | HOH1284 |
| C | HOH1387 |
| C | HOH1596 |
| site_id | AG8 |
| Number of Residues | 14 |
| Details | binding site for residue LMT C 1108 |
| Chain | Residue |
| C | GLN46 |
| C | ARG48 |
| C | GLN134 |
| C | ARG157 |
| C | GLN176 |
| C | GLN178 |
| C | ILE179 |
| C | PHE180 |
| C | GLY181 |
| C | PHE626 |
| C | ASN628 |
| C | HOH1232 |
| C | HOH1585 |
| C | HOH1629 |
| site_id | AG9 |
| Number of Residues | 2 |
| Details | binding site for residue LMT C 1109 |
| Chain | Residue |
| C | TYR387 |
| C | HOH1330 |
| site_id | AH1 |
| Number of Residues | 9 |
| Details | binding site for residue LMT C 1110 |
| Chain | Residue |
| C | ILE29 |
| C | ASN301 |
| C | ASP304 |
| C | ASN307 |
| C | ARG337 |
| C | VAL343 |
| C | LEU347 |
| C | PHE383 |
| C | HOH1364 |
| site_id | AH2 |
| Number of Residues | 16 |
| Details | binding site for residue LMT C 1111 |
| Chain | Residue |
| C | MET458 |
| C | LEU461 |
| C | TYR469 |
| C | GLY570 |
| C | PHE571 |
| C | GLY682 |
| C | SER842 |
| C | GLN872 |
| C | GLN875 |
| C | ASN877 |
| C | PHE883 |
| C | GLN934 |
| C | VAL935 |
| C | LMT1101 |
| C | HOH1376 |
| C | HOH1398 |
| site_id | AH3 |
| Number of Residues | 10 |
| Details | binding site for residue LMT C 1112 |
| Chain | Residue |
| B | ARG170 |
| B | PRO172 |
| C | ASN72 |
| C | MET77 |
| C | MET78 |
| C | ARG97 |
| C | ASN824 |
| C | GLY825 |
| C | PHE870 |
| C | THR874 |
| site_id | AH4 |
| Number of Residues | 5 |
| Details | binding site for residue PTY C 1113 |
| Chain | Residue |
| A | PHE460 |
| A | THR878 |
| C | ASP304 |
| C | LEU388 |
| C | HOH1577 |
| site_id | AH5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL C 1114 |
| Chain | Residue |
| C | ARG310 |
| C | TRP326 |
| C | ALA327 |
| C | ALA328 |
| C | HOH1358 |
| C | HOH1443 |
| E | PRO147 |
| E | ASN148 |
| E | LYS287 |
| site_id | AH6 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 1115 |
| Chain | Residue |
| C | GLU246 |
| C | ILE271 |
| C | HOH1598 |
| site_id | AH7 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 1116 |
| Chain | Residue |
| C | ARG956 |
| C | GLU959 |
| C | ILE960 |
| C | TYR1031 |
| C | ARG1035 |
| C | HOH1294 |
| site_id | AH8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 1117 |
| Chain | Residue |
| C | GLY696 |
| C | TYR697 |
| C | GLY698 |
| C | HOH1461 |
| C | HOH1534 |
| site_id | AH9 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 1118 |
| Chain | Residue |
| C | SER708 |
| C | PHE719 |
| C | PRO720 |
| C | SER722 |
| C | LEU831 |
| C | HOH1209 |
| C | HOH1329 |
| C | HOH1506 |
| site_id | AI1 |
| Number of Residues | 3 |
| Details | binding site for residue GOL C 1119 |
| Chain | Residue |
| C | ASN525 |
| C | HOH1210 |
| F | HOH1573 |
| site_id | AI2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 1120 |
| Chain | Residue |
| C | GLU439 |
| C | GLU957 |
| C | LEU958 |
| C | LEU975 |
| C | HOH1351 |
| site_id | AI3 |
| Number of Residues | 11 |
| Details | binding site for residue LMT D 1101 |
| Chain | Residue |
| D | ASP9 |
| D | ARG10 |
| D | PRO11 |
| D | ILE12 |
| D | PHE22 |
| D | ILE373 |
| D | VAL377 |
| D | HOH1231 |
| E | GLU899 |
| E | TRP901 |
| E | PTY1114 |
| site_id | AI4 |
| Number of Residues | 12 |
| Details | binding site for residue LMT D 1102 |
| Chain | Residue |
| D | TYR37 |
| D | PHE335 |
| D | SER339 |
| D | ALA342 |
| D | THR395 |
| D | VAL402 |
| D | GLN575 |
| D | LYS577 |
| D | ALA986 |
| D | LEU994 |
| D | GLY1001 |
| D | ARG1005 |
| site_id | AI5 |
| Number of Residues | 18 |
| Details | binding site for residue LMT D 1103 |
| Chain | Residue |
| D | LYS81 |
| D | TYR330 |
| D | TYR579 |
| D | ALA623 |
| D | LEU624 |
| D | GLN625 |
| D | PHE626 |
| D | PHE636 |
| D | GLY638 |
| D | PRO674 |
| D | LEU677 |
| D | GLY678 |
| D | LEU679 |
| D | HOH1253 |
| D | HOH1289 |
| D | HOH1298 |
| D | HOH1392 |
| D | HOH1533 |
| site_id | AI6 |
| Number of Residues | 15 |
| Details | binding site for residue LMT D 1104 |
| Chain | Residue |
| D | GLN46 |
| D | ARG48 |
| D | GLN134 |
| D | VAL141 |
| D | ARG157 |
| D | GLN176 |
| D | GLN178 |
| D | ILE179 |
| D | PHE180 |
| D | LEU280 |
| D | PHE626 |
| D | ASN628 |
| D | HOH1202 |
| D | HOH1236 |
| D | HOH1454 |
| site_id | AI7 |
| Number of Residues | 7 |
| Details | binding site for residue LMT D 1105 |
| Chain | Residue |
| D | LEU31 |
| D | PRO33 |
| D | TYR387 |
| D | GLY390 |
| D | PHE391 |
| D | LMT1108 |
| E | LMT1110 |
| site_id | AI8 |
| Number of Residues | 6 |
| Details | binding site for residue LMT D 1106 |
| Chain | Residue |
| D | ILE29 |
| D | ASN301 |
| D | ILE303 |
| D | ASP304 |
| D | ASN307 |
| D | VAL344 |
| site_id | AI9 |
| Number of Residues | 12 |
| Details | binding site for residue LMT D 1107 |
| Chain | Residue |
| D | SER462 |
| D | THR465 |
| D | TYR469 |
| D | GLN875 |
| D | ASN877 |
| D | ALA879 |
| D | PHE883 |
| D | GLN934 |
| D | VAL935 |
| D | VAL938 |
| D | LMT1112 |
| D | HOH1331 |
| site_id | AJ1 |
| Number of Residues | 9 |
| Details | binding site for residue LMT D 1108 |
| Chain | Residue |
| D | PRO38 |
| D | ASP39 |
| D | LEU389 |
| D | GLY390 |
| D | SER392 |
| D | LYS470 |
| D | GLN471 |
| D | LMT1105 |
| D | HOH1313 |
| site_id | AJ2 |
| Number of Residues | 13 |
| Details | binding site for residue LMT D 1109 |
| Chain | Residue |
| D | GLU68 |
| D | ASN72 |
| D | MET77 |
| D | MET78 |
| D | MET80 |
| D | ARG97 |
| D | ASN824 |
| D | GLY825 |
| D | PHE870 |
| D | GLN871 |
| D | THR874 |
| D | GLN875 |
| F | ARG170 |
| site_id | AJ3 |
| Number of Residues | 3 |
| Details | binding site for residue LMT D 1110 |
| Chain | Residue |
| D | ALA623 |
| D | LEU624 |
| D | PHE669 |
| site_id | AJ4 |
| Number of Residues | 8 |
| Details | binding site for residue LMT D 1111 |
| Chain | Residue |
| D | MET1 |
| D | GLY442 |
| D | ALA896 |
| D | LEU897 |
| D | ARG956 |
| D | GLU957 |
| D | HOH1271 |
| F | LEU17 |
| site_id | AJ5 |
| Number of Residues | 8 |
| Details | binding site for residue LMT D 1112 |
| Chain | Residue |
| D | MET458 |
| D | PHE564 |
| D | ASN877 |
| D | ASN929 |
| D | GLN934 |
| D | LEU937 |
| D | MET941 |
| D | LMT1107 |
| site_id | AJ6 |
| Number of Residues | 6 |
| Details | binding site for residue PTY D 1113 |
| Chain | Residue |
| D | PRO30 |
| D | ASP304 |
| D | LEU388 |
| D | HOH1204 |
| D | HOH1395 |
| E | PHE460 |
| site_id | AJ7 |
| Number of Residues | 9 |
| Details | binding site for residue GOL D 1114 |
| Chain | Residue |
| A | PRO147 |
| A | ASN148 |
| A | LYS287 |
| D | ARG310 |
| D | TRP326 |
| D | ALA327 |
| D | ALA328 |
| D | HOH1295 |
| D | HOH1481 |
| site_id | AJ8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 1115 |
| Chain | Residue |
| A | MET607 |
| A | HOH1592 |
| D | PHE145 |
| D | ASN285 |
| D | HOH1206 |
| D | HOH1483 |
| site_id | AJ9 |
| Number of Residues | 9 |
| Details | binding site for residue GOL D 1116 |
| Chain | Residue |
| D | LEU162 |
| D | ASP166 |
| D | ARG771 |
| D | HOH1201 |
| D | HOH1264 |
| D | HOH1382 |
| E | GLY825 |
| E | TYR826 |
| E | HOH1509 |
| site_id | AK1 |
| Number of Residues | 1 |
| Details | binding site for residue GOL D 1117 |
| Chain | Residue |
| D | ILE271 |
| site_id | AK2 |
| Number of Residues | 11 |
| Details | binding site for residue LMT E 1101 |
| Chain | Residue |
| E | ARG10 |
| E | PRO11 |
| E | ILE12 |
| E | ALA15 |
| E | VAL377 |
| E | LEU497 |
| E | LMT1112 |
| F | GLU899 |
| F | TRP901 |
| F | LMT1101 |
| F | HOH1369 |
| site_id | AK3 |
| Number of Residues | 12 |
| Details | binding site for residue LMT E 1102 |
| Chain | Residue |
| D | ARG10 |
| D | PHE13 |
| D | LEU20 |
| E | MET1 |
| E | GLY442 |
| E | ALA446 |
| E | ALA896 |
| E | LEU897 |
| E | ARG956 |
| E | GLU957 |
| E | LMT1113 |
| E | HOH1401 |
| site_id | AK4 |
| Number of Residues | 14 |
| Details | binding site for residue LMT E 1103 |
| Chain | Residue |
| E | GLU36 |
| E | PHE335 |
| E | SER339 |
| E | ALA342 |
| E | THR395 |
| E | VAL402 |
| E | GLN575 |
| E | LYS577 |
| E | LEU994 |
| E | ALA1000 |
| E | GLY1001 |
| E | VAL1004 |
| E | ARG1005 |
| E | HOH1229 |
| site_id | AK5 |
| Number of Residues | 22 |
| Details | binding site for residue LMT E 1104 |
| Chain | Residue |
| E | LYS81 |
| E | TYR330 |
| E | TYR579 |
| E | VAL616 |
| E | ALA623 |
| E | LEU624 |
| E | GLN625 |
| E | PHE626 |
| E | PHE636 |
| E | GLY638 |
| E | PRO674 |
| E | ILE676 |
| E | LEU677 |
| E | GLY678 |
| E | LEU679 |
| E | GLY680 |
| E | ASP867 |
| E | LMT1105 |
| E | HOH1214 |
| E | HOH1262 |
| E | HOH1431 |
| E | HOH1587 |
| site_id | AK6 |
| Number of Residues | 15 |
| Details | binding site for residue LMT E 1105 |
| Chain | Residue |
| E | GLN46 |
| E | ARG48 |
| E | GLN134 |
| E | ARG157 |
| E | GLN176 |
| E | GLN178 |
| E | ILE179 |
| E | PHE180 |
| E | GLY181 |
| E | PHE295 |
| E | PHE626 |
| E | LMT1104 |
| E | GOL1123 |
| E | HOH1201 |
| E | HOH1493 |
| site_id | AK7 |
| Number of Residues | 4 |
| Details | binding site for residue LMT E 1106 |
| Chain | Residue |
| E | TYR387 |
| E | LEU388 |
| E | HOH1340 |
| F | LEU449 |
| site_id | AK8 |
| Number of Residues | 7 |
| Details | binding site for residue LMT E 1107 |
| Chain | Residue |
| E | ASN301 |
| E | ASP304 |
| E | ASN307 |
| E | ARG337 |
| E | ILE340 |
| E | ARG341 |
| E | HOH1277 |
| site_id | AK9 |
| Number of Residues | 16 |
| Details | binding site for residue LMT E 1108 |
| Chain | Residue |
| E | PHE455 |
| E | MET458 |
| E | TYR469 |
| E | ALA473 |
| E | GLY569 |
| E | GLY570 |
| E | PHE571 |
| E | SER842 |
| E | GLN872 |
| E | GLN875 |
| E | ASN877 |
| E | PHE883 |
| E | GLN934 |
| E | VAL935 |
| E | LMT1109 |
| E | HOH1516 |
| site_id | AL1 |
| Number of Residues | 10 |
| Details | binding site for residue LMT E 1109 |
| Chain | Residue |
| E | PHE564 |
| E | GLY569 |
| E | GLY570 |
| E | SER841 |
| E | PHE883 |
| E | VAL887 |
| E | ASN929 |
| E | GLN934 |
| E | MET941 |
| E | LMT1108 |
| site_id | AL2 |
| Number of Residues | 8 |
| Details | binding site for residue LMT E 1110 |
| Chain | Residue |
| D | LMT1105 |
| E | PRO38 |
| E | ASP39 |
| E | GLY390 |
| E | LYS470 |
| E | GLN471 |
| E | GOL1121 |
| E | HOH1437 |
| site_id | AL3 |
| Number of Residues | 1 |
| Details | binding site for residue LMT E 1111 |
| Chain | Residue |
| E | PHE3 |
| site_id | AL4 |
| Number of Residues | 5 |
| Details | binding site for residue LMT E 1112 |
| Chain | Residue |
| E | ILE19 |
| E | ARG366 |
| E | LEU497 |
| E | LMT1101 |
| F | TRP901 |
| site_id | AL5 |
| Number of Residues | 2 |
| Details | binding site for residue LMT E 1113 |
| Chain | Residue |
| D | PHE6 |
| E | LMT1102 |
| site_id | AL6 |
| Number of Residues | 5 |
| Details | binding site for residue PTY E 1114 |
| Chain | Residue |
| D | LMT1101 |
| E | VAL887 |
| E | PHE891 |
| E | TRP901 |
| E | VAL1038 |
| site_id | AL7 |
| Number of Residues | 6 |
| Details | binding site for residue PTY E 1115 |
| Chain | Residue |
| E | PRO30 |
| E | TYR387 |
| E | LEU388 |
| E | HOH1338 |
| F | PHE460 |
| F | ILE881 |
| site_id | AL8 |
| Number of Residues | 7 |
| Details | binding site for residue GOL E 1116 |
| Chain | Residue |
| E | SER900 |
| E | THR902 |
| E | LEU903 |
| E | ARG1035 |
| E | VAL1038 |
| E | HOH1307 |
| E | HOH1406 |
| site_id | AL9 |
| Number of Residues | 2 |
| Details | binding site for residue GOL E 1117 |
| Chain | Residue |
| E | LYS585 |
| E | PHE667 |
| site_id | AM1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL E 1118 |
| Chain | Residue |
| E | VAL584 |
| E | LEU621 |
| E | ASN622 |
| E | ALA623 |
| E | THR632 |
| E | GLY633 |
| E | THR634 |
| E | PHE669 |
| site_id | AM2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL E 1119 |
| Chain | Residue |
| E | GLU36 |
| E | PRO136 |
| E | THR137 |
| E | LEU138 |
| E | PRO332 |
| E | LEU677 |
| E | HOH1212 |
| E | HOH1592 |
| site_id | AM3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL E 1120 |
| Chain | Residue |
| E | ARG421 |
| E | GLU439 |
| E | GLU957 |
| E | HOH1240 |
| E | HOH1491 |
| F | GLN258 |
| F | ASP259 |
| site_id | AM4 |
| Number of Residues | 11 |
| Details | binding site for residue GOL E 1121 |
| Chain | Residue |
| E | PRO33 |
| E | VAL34 |
| E | SER35 |
| E | TYR37 |
| E | PRO38 |
| E | ASP39 |
| E | GLN296 |
| E | PRO298 |
| E | ALA300 |
| E | SER392 |
| E | LMT1110 |
| site_id | AM5 |
| Number of Residues | 9 |
| Details | binding site for residue GOL E 1122 |
| Chain | Residue |
| E | GLU50 |
| E | ASP87 |
| E | VAL89 |
| E | GLY276 |
| E | SER277 |
| E | ASN628 |
| E | GOL1123 |
| E | HOH1323 |
| E | HOH1463 |
| site_id | AM6 |
| Number of Residues | 8 |
| Details | binding site for residue GOL E 1123 |
| Chain | Residue |
| E | GLY183 |
| E | GLU184 |
| E | GLY276 |
| E | SER277 |
| E | ARG774 |
| E | LMT1105 |
| E | GOL1122 |
| E | HOH1205 |
| site_id | AM7 |
| Number of Residues | 11 |
| Details | binding site for residue LMT F 1101 |
| Chain | Residue |
| E | PHE13 |
| E | LMT1101 |
| F | MET1 |
| F | PHE3 |
| F | GLY442 |
| F | ALA896 |
| F | LEU897 |
| F | GLU899 |
| F | ARG956 |
| F | GLU957 |
| F | HOH1204 |
| site_id | AM8 |
| Number of Residues | 11 |
| Details | binding site for residue LMT F 1102 |
| Chain | Residue |
| D | GLU899 |
| D | TRP901 |
| D | HOH1290 |
| F | ASP9 |
| F | ARG10 |
| F | PRO11 |
| F | ILE12 |
| F | ALA15 |
| F | VAL377 |
| F | LEU494 |
| F | PTY1114 |
| site_id | AM9 |
| Number of Residues | 14 |
| Details | binding site for residue LMT F 1103 |
| Chain | Residue |
| F | PHE335 |
| F | ASP338 |
| F | SER339 |
| F | THR395 |
| F | PHE399 |
| F | VAL402 |
| F | GLN575 |
| F | LYS577 |
| F | LEU994 |
| F | ALA1000 |
| F | GLY1001 |
| F | ARG1005 |
| F | VAL1012 |
| F | HOH1221 |
| site_id | AN1 |
| Number of Residues | 18 |
| Details | binding site for residue LMT F 1104 |
| Chain | Residue |
| F | LYS81 |
| F | TYR579 |
| F | ILE581 |
| F | VAL616 |
| F | ALA623 |
| F | LEU624 |
| F | GLN625 |
| F | PHE636 |
| F | GLY638 |
| F | PRO674 |
| F | ILE676 |
| F | LEU677 |
| F | GLY678 |
| F | LEU679 |
| F | GLY680 |
| F | GOL1117 |
| F | HOH1246 |
| F | HOH1473 |
| site_id | AN2 |
| Number of Residues | 14 |
| Details | binding site for residue LMT F 1105 |
| Chain | Residue |
| F | GLN46 |
| F | ARG48 |
| F | GLN134 |
| F | ARG157 |
| F | GLN176 |
| F | GLN178 |
| F | ILE179 |
| F | PHE180 |
| F | GLY181 |
| F | PHE295 |
| F | PHE626 |
| F | HOH1343 |
| F | HOH1465 |
| F | HOH1471 |
| site_id | AN3 |
| Number of Residues | 7 |
| Details | binding site for residue LMT F 1106 |
| Chain | Residue |
| F | PRO38 |
| F | ASP39 |
| F | LEU389 |
| F | GLY390 |
| F | LYS470 |
| F | GLN471 |
| F | HOH1404 |
| site_id | AN4 |
| Number of Residues | 2 |
| Details | binding site for residue LMT F 1107 |
| Chain | Residue |
| F | ASN301 |
| F | ASP304 |
| site_id | AN5 |
| Number of Residues | 3 |
| Details | binding site for residue LMT F 1108 |
| Chain | Residue |
| F | MET458 |
| F | TYR469 |
| F | LMT1109 |
| site_id | AN6 |
| Number of Residues | 8 |
| Details | binding site for residue LMT F 1109 |
| Chain | Residue |
| F | MET458 |
| F | PHE564 |
| F | GLY569 |
| F | SER841 |
| F | SER843 |
| F | ASN929 |
| F | GLN934 |
| F | LMT1108 |
| site_id | AN7 |
| Number of Residues | 14 |
| Details | binding site for residue LMT F 1110 |
| Chain | Residue |
| E | ARG170 |
| E | GLY770 |
| E | ARG771 |
| F | GLU68 |
| F | GLU69 |
| F | MET77 |
| F | MET78 |
| F | MET80 |
| F | ARG97 |
| F | ARG822 |
| F | ASN824 |
| F | GLY825 |
| F | PHE870 |
| F | THR874 |
| site_id | AN8 |
| Number of Residues | 4 |
| Details | binding site for residue LMT F 1111 |
| Chain | Residue |
| F | LYS585 |
| F | PHE667 |
| F | PHE719 |
| F | ASP834 |
| site_id | AN9 |
| Number of Residues | 1 |
| Details | binding site for residue LMT F 1112 |
| Chain | Residue |
| F | PHE920 |
| site_id | AO1 |
| Number of Residues | 6 |
| Details | binding site for residue LMT F 1113 |
| Chain | Residue |
| C | HIS502 |
| F | ASN525 |
| F | PHE528 |
| F | HOH1329 |
| F | HOH1334 |
| F | HOH1416 |
| site_id | AO2 |
| Number of Residues | 4 |
| Details | binding site for residue PTY F 1114 |
| Chain | Residue |
| D | TRP901 |
| F | ILE373 |
| F | LEU498 |
| F | LMT1102 |
| site_id | AO3 |
| Number of Residues | 5 |
| Details | binding site for residue PTY F 1115 |
| Chain | Residue |
| D | VAL456 |
| F | PRO30 |
| F | TYR387 |
| F | LEU388 |
| F | HOH1361 |
| site_id | AO4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL F 1116 |
| Chain | Residue |
| F | SER204 |
| F | GLY752 |
| F | THR756 |
| F | HOH1442 |
| site_id | AO5 |
| Number of Residues | 12 |
| Details | binding site for residue GOL F 1117 |
| Chain | Residue |
| F | LYS81 |
| F | LEU624 |
| F | GLN625 |
| F | SER686 |
| F | LEU687 |
| F | TYR688 |
| F | ASP830 |
| F | LEU831 |
| F | ILE832 |
| F | ASP867 |
| F | LMT1104 |
| F | HOH1357 |
| site_id | AO6 |
| Number of Residues | 6 |
| Details | binding site for residue GOL F 1118 |
| Chain | Residue |
| F | GLY698 |
| F | GLN701 |
| F | SER702 |
| F | ASN705 |
| F | ASN727 |
| F | HOH1367 |
| site_id | AO7 |
| Number of Residues | 9 |
| Details | binding site for residue GOL F 1119 |
| Chain | Residue |
| D | ALA118 |
| D | LEU120 |
| F | GLN216 |
| F | ARG242 |
| F | TYR762 |
| F | ASN764 |
| F | ASP765 |
| F | HOH1229 |
| F | HOH1430 |
| site_id | AO8 |
| Number of Residues | 5 |
| Details | binding site for residue GOL F 1120 |
| Chain | Residue |
| F | GLU439 |
| F | GLU957 |
| F | LEU958 |
| F | GLN961 |
| F | HOH1211 |
