7CVU
Crystal structure of Catechol o-methyl transferase (COMT) from Niastella koreensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008171 | molecular_function | O-methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0008168 | molecular_function | methyltransferase activity |
| B | 0008171 | molecular_function | O-methyltransferase activity |
| B | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0032259 | biological_process | methylation |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0008168 | molecular_function | methyltransferase activity |
| C | 0008171 | molecular_function | O-methyltransferase activity |
| C | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| C | 0016740 | molecular_function | transferase activity |
| C | 0032259 | biological_process | methylation |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0008168 | molecular_function | methyltransferase activity |
| D | 0008171 | molecular_function | O-methyltransferase activity |
| D | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| D | 0016740 | molecular_function | transferase activity |
| D | 0032259 | biological_process | methylation |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 301 |
| Chain | Residue |
| C | CYS56 |
| C | GLN57 |
| C | LYS59 |
| C | ASP134 |
| C | ARG157 |
| C | TYR212 |
| C | HOH403 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL D 301 |
| Chain | Residue |
| D | LYS59 |
| D | ASP134 |
| D | ARG157 |
| D | TYR212 |
| D | HOH404 |
| D | CYS56 |
| D | GLN57 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 19 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33596655","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CVV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33596655","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"7CVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33596655","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CVV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33596655","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CVW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CVX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
