7CUY
Crystal structure of Primo-1
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003993 | molecular_function | acid phosphatase activity |
| A | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| A | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| A | 0004726 | molecular_function | non-membrane spanning protein tyrosine phosphatase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006470 | biological_process | protein dephosphorylation |
| B | 0003993 | molecular_function | acid phosphatase activity |
| B | 0004721 | molecular_function | phosphoprotein phosphatase activity |
| B | 0004725 | molecular_function | protein tyrosine phosphatase activity |
| B | 0004726 | molecular_function | non-membrane spanning protein tyrosine phosphatase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006470 | biological_process | protein dephosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue EPE A 201 |
| Chain | Residue |
| A | CYS9 |
| A | ASP124 |
| A | TYR126 |
| A | TYR127 |
| A | HOH307 |
| A | HOH312 |
| A | LEU10 |
| A | GLY11 |
| A | ASN12 |
| A | ILE13 |
| A | CYS14 |
| A | ARG15 |
| A | TRP45 |
| A | HIS46 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | binding site for residue EPE B 201 |
| Chain | Residue |
| B | CYS9 |
| B | LEU10 |
| B | GLY11 |
| B | ASN12 |
| B | ILE13 |
| B | CYS14 |
| B | ARG15 |
| B | TRP45 |
| B | HIS46 |
| B | ASP124 |
| B | TYR126 |
| B | HOH314 |
Functional Information from PROSITE/UniProt
| site_id | PS00028 |
| Number of Residues | 23 |
| Details | ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. Cvva.CaafMkerlqkleHhhhh.H |
| Chain | Residue | Details |
| A | CYS141-HIS163 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000250|UniProtKB:P11064 |
| Chain | Residue | Details |
| B | CYS9 | |
| A | CYS9 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P11064 |
| Chain | Residue | Details |
| B | ARG15 | |
| A | ARG15 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P11064 |
| Chain | Residue | Details |
| B | ASP124 | |
| A | ASP124 |
