7CU0
Crystal structure of Streptomyces albogriseolus flavin-dependent tryptophan 6-halogenase Thal in complex with tryptophan
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue TRP A 601 |
| Chain | Residue |
| A | PRO53 |
| A | PHE465 |
| A | TRP466 |
| A | SER470 |
| A | HOH859 |
| A | HOH918 |
| A | LYS79 |
| A | HIS110 |
| A | PRO111 |
| A | PHE112 |
| A | GLU358 |
| A | TYR454 |
| A | TYR455 |
| A | GLU461 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue TRP B 601 |
| Chain | Residue |
| B | PRO53 |
| B | HIS110 |
| B | PRO111 |
| B | PHE112 |
| B | GLU358 |
| B | TYR454 |
| B | TYR455 |
| B | GLU461 |
| B | PHE465 |
| B | TRP466 |
| B | SER470 |
| B | HOH738 |
| B | HOH780 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"30559288","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"33465708","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31589794","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33465708","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6SLS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6SLT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CU1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"33465708","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CU1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31589794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6SLS","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31589794","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6SLS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6SLT","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30559288","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31589794","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33465708","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6H44","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6SLT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CU0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"E9P162","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for activity","evidences":[{"source":"UniProtKB","id":"P95480","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
