Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

7CSE

AtPrR1 with NADP+ and (-)lariciresinol

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0009807	biological_process	lignan biosynthetic process
A	0010283	molecular_function	pinoresinol reductase activity
A	0016491	molecular_function	oxidoreductase activity
A	0050664	molecular_function	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
B	0005737	cellular_component	cytoplasm
B	0009807	biological_process	lignan biosynthetic process
B	0010283	molecular_function	pinoresinol reductase activity
B	0016491	molecular_function	oxidoreductase activity
B	0050664	molecular_function	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
C	0005737	cellular_component	cytoplasm
C	0009807	biological_process	lignan biosynthetic process
C	0010283	molecular_function	pinoresinol reductase activity
C	0016491	molecular_function	oxidoreductase activity
C	0050664	molecular_function	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
D	0005737	cellular_component	cytoplasm
D	0009807	biological_process	lignan biosynthetic process
D	0010283	molecular_function	pinoresinol reductase activity
D	0016491	molecular_function	oxidoreductase activity
D	0050664	molecular_function	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
E	0005737	cellular_component	cytoplasm
E	0009807	biological_process	lignan biosynthetic process
E	0010283	molecular_function	pinoresinol reductase activity
E	0016491	molecular_function	oxidoreductase activity
E	0050664	molecular_function	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor
F	0005737	cellular_component	cytoplasm
F	0009807	biological_process	lignan biosynthetic process
F	0010283	molecular_function	pinoresinol reductase activity
F	0016491	molecular_function	oxidoreductase activity
F	0050664	molecular_function	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue GFR E 401

Chain	Residue
E	PHE94
E	NDP402
E	HOH510
E	GLY124
E	MET125
E	TYR169
E	PHE170
E	ASN173
E	GLN176
E	MET177
E	HIS276

site_id	AC2
Number of Residues	29
Details	binding site for residue NDP E 402

Chain	Residue
E	GLY16
E	ALA17
E	THR18
E	GLY19
E	TYR20
E	ILE21
E	ARG41
E	LYS50
E	PHE69
E	ALA88
E	MET89
E	SER90
E	GLY91
E	VAL92
E	ARG95
E	ASN98
E	SER121
E	GLU122
E	PHE123
E	LYS144
E	ALA164
E	CYS165
E	PHE166
E	PHE170
E	GFR401
E	HOH518
E	HOH521
E	HOH523
E	HOH527

site_id	AC3
Number of Residues	12
Details	binding site for residue GFR F 401

Chain	Residue
F	PHE94
F	GLY124
F	MET125
F	TYR169
F	PHE170
F	ASN173
F	MET177
F	THR179
F	GLY273
F	HIS276
F	PHE277
F	NDP402

site_id	AC4
Number of Residues	31
Details	binding site for residue NDP F 402

Chain	Residue
F	GLY16
F	ALA17
F	THR18
F	GLY19
F	TYR20
F	ILE21
F	ARG41
F	LYS50
F	PHE69
F	ALA88
F	MET89
F	SER90
F	GLY91
F	VAL92
F	ARG95
F	ASN98
F	SER121
F	GLU122
F	PHE123
F	GLY124
F	LYS144
F	ALA164
F	CYS165
F	PHE166
F	PHE170
F	GFR401
F	HOH506
F	HOH507
F	HOH519
F	HOH521
F	HOH537

site_id	AC5
Number of Residues	13
Details	binding site for residue GFR A 401

Chain	Residue
A	PHE94
A	GLY124
A	MET125
A	TYR169
A	PHE170
A	ASN173
A	MET177
A	VAL178
A	THR179
A	HIS276
A	PHE277
A	NDP402
B	LEU46

site_id	AC6
Number of Residues	32
Details	binding site for residue NDP A 402

Chain	Residue
A	GLY19
A	TYR20
A	ILE21
A	ARG41
A	LYS50
A	PHE69
A	ALA88
A	MET89
A	SER90
A	GLY91
A	VAL92
A	ARG95
A	SER96
A	ASN98
A	SER121
A	GLU122
A	PHE123
A	GLY124
A	LYS144
A	ALA164
A	CYS165
A	PHE166
A	PHE170
A	GFR401
A	HOH527
A	HOH534
A	HOH551
A	HOH562
A	HOH574
A	GLY16
A	ALA17
A	THR18

site_id	AC7
Number of Residues	13
Details	binding site for residue GFR B 401

Chain	Residue
A	LEU46
B	PHE94
B	GLY124
B	MET125
B	TYR169
B	PHE170
B	ASN173
B	MET177
B	VAL178
B	THR179
B	HIS276
B	NDP402
B	HOH506

site_id	AC8
Number of Residues	30
Details	binding site for residue NDP B 402

Chain	Residue
B	GLY16
B	ALA17
B	THR18
B	GLY19
B	TYR20
B	ILE21
B	ARG41
B	LYS50
B	PHE69
B	ALA88
B	MET89
B	SER90
B	GLY91
B	ARG95
B	ASN98
B	SER121
B	GLU122
B	PHE123
B	GLY124
B	LYS144
B	ALA164
B	CYS165
B	PHE166
B	PHE170
B	GFR401
B	HOH508
B	HOH509
B	HOH537
B	HOH538
B	HOH552

site_id	AC9
Number of Residues	13
Details	binding site for residue GFR C 401

Chain	Residue
C	VAL92
C	PHE94
C	GLY124
C	MET125
C	LYS144
C	TYR169
C	PHE170
C	ASN173
C	MET177
C	THR179
C	HIS276
C	PHE277
C	NDP402

site_id	AD1
Number of Residues	29
Details	binding site for residue NDP C 402

Chain	Residue
C	GLY16
C	ALA17
C	THR18
C	GLY19
C	TYR20
C	ILE21
C	ARG41
C	LYS50
C	PHE69
C	ALA88
C	MET89
C	SER90
C	GLY91
C	ARG95
C	ASN98
C	SER121
C	GLU122
C	PHE123
C	GLY124
C	LYS144
C	ALA164
C	CYS165
C	PHE166
C	PHE170
C	GFR401
C	HOH516
C	HOH523
C	HOH524
C	HOH529

site_id	AD2
Number of Residues	12
Details	binding site for residue GFR D 401

Chain	Residue
D	PHE94
D	GLY124
D	MET125
D	TYR169
D	ASN173
D	GLN176
D	MET177
D	VAL178
D	HIS276
D	PHE277
D	NDP402
D	HOH551

site_id	AD3
Number of Residues	29
Details	binding site for residue NDP D 402

Chain	Residue
D	GLY16
D	ALA17
D	THR18
D	GLY19
D	TYR20
D	ILE21
D	ARG41
D	LYS50
D	ALA88
D	MET89
D	SER90
D	GLY91
D	ARG95
D	ASN98
D	SER121
D	GLU122
D	PHE123
D	GLY124
D	LYS144
D	ALA164
D	CYS165
D	PHE166
D	PHE170
D	GFR401
D	HOH515
D	HOH518
D	HOH521
D	HOH532
D	HOH549

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"UniProtKB","id":"Q9LD14","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	54
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33990581","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CSA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CSB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33990581","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CSB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CSC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33990581","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CSA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CSD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33990581","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CSC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"33990581","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CSB","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)