7CSD
AtPrR1 with NADP+ and (+)lariciresinol
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009807 | biological_process | lignan biosynthetic process |
| A | 0010283 | molecular_function | pinoresinol reductase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| B | 0009807 | biological_process | lignan biosynthetic process |
| B | 0010283 | molecular_function | pinoresinol reductase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| C | 0009807 | biological_process | lignan biosynthetic process |
| C | 0010283 | molecular_function | pinoresinol reductase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| D | 0009807 | biological_process | lignan biosynthetic process |
| D | 0010283 | molecular_function | pinoresinol reductase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue GFU C 401 |
| Chain | Residue |
| C | VAL92 |
| C | THR179 |
| C | GLY273 |
| C | HIS276 |
| C | PHE277 |
| C | NDP402 |
| C | HOH505 |
| C | HOH537 |
| D | LEU46 |
| C | PHE94 |
| C | GLY124 |
| C | MET125 |
| C | TYR169 |
| C | ASN173 |
| C | GLN176 |
| C | MET177 |
| C | VAL178 |
| site_id | AC2 |
| Number of Residues | 35 |
| Details | binding site for residue NDP C 402 |
| Chain | Residue |
| C | GLY16 |
| C | ALA17 |
| C | THR18 |
| C | GLY19 |
| C | TYR20 |
| C | ILE21 |
| C | ARG41 |
| C | LYS50 |
| C | PHE69 |
| C | ALA88 |
| C | MET89 |
| C | SER90 |
| C | GLY91 |
| C | ARG95 |
| C | ASN98 |
| C | SER121 |
| C | GLU122 |
| C | PHE123 |
| C | GLY124 |
| C | LYS144 |
| C | ALA164 |
| C | CYS165 |
| C | PHE166 |
| C | PHE170 |
| C | GFU401 |
| C | HOH508 |
| C | HOH549 |
| C | HOH559 |
| C | HOH561 |
| C | HOH580 |
| C | HOH616 |
| C | HOH619 |
| C | HOH665 |
| C | HOH683 |
| C | HOH737 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue GFU D 401 |
| Chain | Residue |
| C | LEU46 |
| D | VAL92 |
| D | PHE94 |
| D | GLY124 |
| D | MET125 |
| D | TYR169 |
| D | ASN173 |
| D | GLN176 |
| D | MET177 |
| D | VAL178 |
| D | THR179 |
| D | GLY273 |
| D | HIS276 |
| D | NDP402 |
| D | HOH532 |
| D | HOH676 |
| site_id | AC4 |
| Number of Residues | 34 |
| Details | binding site for residue NDP D 402 |
| Chain | Residue |
| D | HOH650 |
| D | HOH657 |
| D | HOH705 |
| D | GLY16 |
| D | ALA17 |
| D | THR18 |
| D | GLY19 |
| D | TYR20 |
| D | ILE21 |
| D | ARG41 |
| D | LYS50 |
| D | PHE69 |
| D | ALA88 |
| D | MET89 |
| D | SER90 |
| D | GLY91 |
| D | VAL92 |
| D | ARG95 |
| D | ASN98 |
| D | SER121 |
| D | GLU122 |
| D | PHE123 |
| D | GLY124 |
| D | LYS144 |
| D | ALA164 |
| D | CYS165 |
| D | PHE166 |
| D | PHE170 |
| D | GFU401 |
| D | HOH529 |
| D | HOH530 |
| D | HOH579 |
| D | HOH583 |
| D | HOH633 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | binding site for residue GFU A 401 |
| Chain | Residue |
| A | VAL92 |
| A | PHE94 |
| A | GLY124 |
| A | MET125 |
| A | TYR169 |
| A | PHE170 |
| A | ASN173 |
| A | GLN176 |
| A | MET177 |
| A | VAL178 |
| A | THR179 |
| A | GLY273 |
| A | HIS276 |
| A | PHE277 |
| A | NDP402 |
| A | HOH534 |
| A | HOH552 |
| B | LEU46 |
| site_id | AC6 |
| Number of Residues | 33 |
| Details | binding site for residue NDP A 402 |
| Chain | Residue |
| A | GLY16 |
| A | ALA17 |
| A | THR18 |
| A | GLY19 |
| A | TYR20 |
| A | ILE21 |
| A | ARG41 |
| A | LYS50 |
| A | ALA88 |
| A | MET89 |
| A | SER90 |
| A | GLY91 |
| A | VAL92 |
| A | ARG95 |
| A | ASN98 |
| A | SER121 |
| A | GLU122 |
| A | PHE123 |
| A | GLY124 |
| A | LYS144 |
| A | ALA164 |
| A | CYS165 |
| A | PHE166 |
| A | PHE170 |
| A | GFU401 |
| A | HOH526 |
| A | HOH528 |
| A | HOH530 |
| A | HOH563 |
| A | HOH569 |
| A | HOH600 |
| A | HOH614 |
| A | HOH629 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue GFU B 401 |
| Chain | Residue |
| A | LEU46 |
| B | VAL92 |
| B | PHE94 |
| B | GLY124 |
| B | MET125 |
| B | TYR169 |
| B | ASN173 |
| B | GLN176 |
| B | MET177 |
| B | VAL178 |
| B | THR179 |
| B | GLY273 |
| B | HIS276 |
| B | PHE277 |
| B | NDP402 |
| B | HOH537 |
| B | HOH557 |
| B | HOH601 |
| site_id | AC8 |
| Number of Residues | 34 |
| Details | binding site for residue NDP B 402 |
| Chain | Residue |
| B | GLY16 |
| B | ALA17 |
| B | THR18 |
| B | GLY19 |
| B | TYR20 |
| B | ILE21 |
| B | ARG41 |
| B | LYS50 |
| B | PHE69 |
| B | ALA88 |
| B | MET89 |
| B | SER90 |
| B | GLY91 |
| B | VAL92 |
| B | ARG95 |
| B | ASN98 |
| B | SER121 |
| B | GLU122 |
| B | PHE123 |
| B | GLY124 |
| B | LYS144 |
| B | ALA164 |
| B | CYS165 |
| B | PHE166 |
| B | PHE170 |
| B | GFU401 |
| B | HOH527 |
| B | HOH529 |
| B | HOH547 |
| B | HOH563 |
| B | HOH574 |
| B | HOH607 |
| B | HOH619 |
| B | HOH661 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:Q9LD14 |
| Chain | Residue | Details |
| C | LYS144 | |
| D | LYS144 | |
| A | LYS144 | |
| B | LYS144 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 36 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33990581, ECO:0007744|PDB:7CSA, ECO:0007744|PDB:7CSB |
| Chain | Residue | Details |
| C | THR18 | |
| D | THR18 | |
| D | TYR20 | |
| D | ILE21 | |
| D | ARG41 | |
| D | LYS50 | |
| D | SER90 | |
| D | SER121 | |
| D | LYS144 | |
| D | PHE166 | |
| A | THR18 | |
| C | TYR20 | |
| A | TYR20 | |
| A | ILE21 | |
| A | ARG41 | |
| A | LYS50 | |
| A | SER90 | |
| A | SER121 | |
| A | LYS144 | |
| A | PHE166 | |
| B | THR18 | |
| B | TYR20 | |
| C | ILE21 | |
| B | ILE21 | |
| B | ARG41 | |
| B | LYS50 | |
| B | SER90 | |
| B | SER121 | |
| B | LYS144 | |
| B | PHE166 | |
| C | ARG41 | |
| C | LYS50 | |
| C | SER90 | |
| C | SER121 | |
| C | LYS144 | |
| C | PHE166 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33990581, ECO:0007744|PDB:7CSB, ECO:0007744|PDB:7CSC |
| Chain | Residue | Details |
| C | GLY91 | |
| A | ARG95 | |
| A | ASN98 | |
| A | MET125 | |
| B | GLY91 | |
| B | ARG95 | |
| B | ASN98 | |
| B | MET125 | |
| C | ARG95 | |
| C | ASN98 | |
| C | MET125 | |
| D | GLY91 | |
| D | ARG95 | |
| D | ASN98 | |
| D | MET125 | |
| A | GLY91 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33990581, ECO:0007744|PDB:7CSA, ECO:0007744|PDB:7CSD |
| Chain | Residue | Details |
| C | GLU122 | |
| D | GLU122 | |
| A | GLU122 | |
| B | GLU122 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33990581, ECO:0007744|PDB:7CSC |
| Chain | Residue | Details |
| C | MET177 | |
| D | MET177 | |
| A | MET177 | |
| B | MET177 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:33990581, ECO:0007744|PDB:7CSB |
| Chain | Residue | Details |
| C | VAL178 | |
| D | VAL178 | |
| A | VAL178 | |
| B | VAL178 |
