7CSA

AtPrR1 with NADP+

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009807	biological_process	lignan biosynthetic process
A	0010283	molecular_function	pinoresinol reductase activity
A	0016491	molecular_function	oxidoreductase activity
B	0009807	biological_process	lignan biosynthetic process
B	0010283	molecular_function	pinoresinol reductase activity
B	0016491	molecular_function	oxidoreductase activity
C	0009807	biological_process	lignan biosynthetic process
C	0010283	molecular_function	pinoresinol reductase activity
C	0016491	molecular_function	oxidoreductase activity
D	0009807	biological_process	lignan biosynthetic process
D	0010283	molecular_function	pinoresinol reductase activity
D	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	33
Details	binding site for residue NDP A 401

Chain	Residue
A	GLY16
A	ALA88
A	MET89
A	SER90
A	VAL92
A	SER121
A	GLU122
A	PHE123
A	GLY124
A	LYS144
A	ALA164
A	ALA17
A	CYS165
A	PHE166
A	PHE170
A	HOH513
A	HOH515
A	HOH530
A	HOH542
A	HOH548
A	HOH549
A	HOH578
A	THR18
A	HOH598
A	HOH602
A	HOH622
A	HOH651
A	GLY19
A	TYR20
A	ILE21
A	ARG41
A	LYS50
A	PHE69

---

site_id	AC2
Number of Residues	32
Details	binding site for residue NDP B 401

Chain	Residue
B	GLY16
B	ALA17
B	THR18
B	GLY19
B	TYR20
B	ILE21
B	ARG41
B	LYS50
B	ALA88
B	MET89
B	SER90
B	VAL92
B	SER121
B	GLU122
B	PHE123
B	GLY124
B	LYS144
B	ALA164
B	CYS165
B	PHE166
B	PHE170
B	HOH520
B	HOH522
B	HOH532
B	HOH562
B	HOH566
B	HOH567
B	HOH573
B	HOH590
B	HOH616
B	HOH650
B	HOH683

---

site_id	AC3
Number of Residues	35
Details	binding site for residue NDP C 401

Chain	Residue
C	HOH860
C	GLY16
C	ALA17
C	THR18
C	GLY19
C	TYR20
C	ILE21
C	ARG41
C	LYS50
C	PHE69
C	ALA88
C	MET89
C	SER90
C	VAL92
C	SER121
C	GLU122
C	PHE123
C	GLY124
C	LYS144
C	ALA164
C	CYS165
C	PHE166
C	PHE170
C	HOH526
C	HOH550
C	HOH553
C	HOH585
C	HOH586
C	HOH587
C	HOH611
C	HOH625
C	HOH647
C	HOH679
C	HOH681
C	HOH706

---

site_id	AC4
Number of Residues	31
Details	binding site for residue NDP D 401

Chain	Residue
D	GLY16
D	ALA17
D	THR18
D	GLY19
D	TYR20
D	ILE21
D	ARG41
D	LYS50
D	ALA88
D	MET89
D	SER90
D	SER121
D	GLU122
D	PHE123
D	LYS144
D	ALA164
D	CYS165
D	PHE166
D	PHE170
D	HOH520
D	HOH522
D	HOH533
D	HOH546
D	HOH579
D	HOH583
D	HOH588
D	HOH627
D	HOH644
D	HOH677
D	HOH687
D	HOH701

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:Q9LD14

Chain	Residue	Details
A	LYS144
B	LYS144
C	LYS144
D	LYS144

---

site_id	SWS_FT_FI2
Number of Residues	36
Details	BINDING: BINDING => ECO:0000269|PubMed:33990581, ECO:0007744|PDB:7CSA, ECO:0007744|PDB:7CSB

Chain	Residue	Details
A	THR18
B	THR18
B	TYR20
B	ILE21
B	ARG41
B	LYS50
B	SER90
B	SER121
B	LYS144
B	PHE166
C	THR18
A	TYR20
C	TYR20
C	ILE21
C	ARG41
C	LYS50
C	SER90
C	SER121
C	LYS144
C	PHE166
D	THR18
D	TYR20
A	ILE21
D	ILE21
D	ARG41
D	LYS50
D	SER90
D	SER121
D	LYS144
D	PHE166
A	ARG41
A	LYS50
A	SER90
A	SER121
A	LYS144
A	PHE166

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:33990581, ECO:0007744|PDB:7CSB, ECO:0007744|PDB:7CSC

Chain	Residue	Details
A	GLY91
C	ARG95
C	ASN98
C	MET125
D	GLY91
D	ARG95
D	ASN98
D	MET125
A	ARG95
A	ASN98
A	MET125
B	GLY91
B	ARG95
B	ASN98
B	MET125
C	GLY91

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:33990581, ECO:0007744|PDB:7CSA, ECO:0007744|PDB:7CSD

Chain	Residue	Details
A	GLU122
B	GLU122
C	GLU122
D	GLU122

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:33990581, ECO:0007744|PDB:7CSC

Chain	Residue	Details
A	MET177
B	MET177
C	MET177
D	MET177

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:33990581, ECO:0007744|PDB:7CSB

Chain	Residue	Details
A	VAL178
B	VAL178
C	VAL178
D	VAL178

---