7CMC

CRYSTAL STRUCTURE OF DEOXYHYPUSINE SYNTHASE FROM PYROCOCCUS HORIKOSHII

Replaces:  4P63

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0008612	biological_process	peptidyl-lysine modification to peptidyl-hypusine
A	0016740	molecular_function	transferase activity
A	0034038	molecular_function	deoxyhypusine synthase activity
B	0005737	cellular_component	cytoplasm
B	0008612	biological_process	peptidyl-lysine modification to peptidyl-hypusine
B	0016740	molecular_function	transferase activity
B	0034038	molecular_function	deoxyhypusine synthase activity
C	0005737	cellular_component	cytoplasm
C	0008612	biological_process	peptidyl-lysine modification to peptidyl-hypusine
C	0016740	molecular_function	transferase activity
C	0034038	molecular_function	deoxyhypusine synthase activity
D	0005737	cellular_component	cytoplasm
D	0008612	biological_process	peptidyl-lysine modification to peptidyl-hypusine
D	0016740	molecular_function	transferase activity
D	0034038	molecular_function	deoxyhypusine synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	29
Details	binding site for residue NAD A 401

Chain	Residue
A	THR74
A	ILE136
A	ASP214
A	GLY260
A	GLY261
A	SER262
A	SER285
A	THR286
A	ALA287
A	GLY319
A	ASP320
A	SER75
A	ALA321
A	HOH515
A	HOH528
D	SER262
D	HIS266
D	ASP291
D	SER293
D	LEU294
D	SER295
D	NAD401
A	ASN76
A	SER79
A	THR101
A	ALA102
A	GLY103
A	GLU106
A	GLU107

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site_id	AC2
Number of Residues	24
Details	binding site for residue NAD D 401

Chain	Residue
A	SER262
A	LEU263
A	HIS266
A	NAD401
D	THR74
D	SER75
D	ASN76
D	SER79
D	THR101
D	ALA102
D	GLY103
D	GLU106
D	GLU107
D	ASP214
D	GLY260
D	GLY261
D	SER262
D	SER285
D	THR286
D	ALA287
D	GLY319
D	ASP320
D	ALA321
D	HOH546

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