7CJT
Crystal Structure of SETDB1 Tudor domain in complexed with (R,R)-59
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue G09 D 501 |
| Chain | Residue |
| D | THR210 |
| D | THR212 |
| D | TYR268 |
| D | TRP275 |
| D | TYR277 |
| D | ASP299 |
| D | TYR301 |
| D | GLU386 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue G09 A 501 |
| Chain | Residue |
| A | THR212 |
| A | TYR268 |
| A | TYR277 |
| A | PHE297 |
| A | ASP299 |
| A | TYR301 |
| A | GLU386 |
| B | ASP270 |
| B | TRP275 |
| B | G09501 |
| A | THR210 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue G09 B 501 |
| Chain | Residue |
| A | G09501 |
| B | THR212 |
| B | TYR268 |
| B | TRP275 |
| B | ASP299 |
| B | GLU386 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue G09 C 501 |
| Chain | Residue |
| B | ASP331 |
| B | GLU334 |
| B | THR338 |
| B | ALA339 |
| B | PRO341 |
| B | ASN342 |
| C | THR210 |
| C | THR212 |
| C | TYR268 |
| C | TRP275 |
| C | TYR277 |
| C | PHE297 |
| C | ASP299 |
| C | TYR301 |
| C | GLU386 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 200 |
| Details | Domain: {"description":"Tudor 1; degenerate","evidences":[{"source":"PubMed","id":"29234025","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6BHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 252 |
| Details | Domain: {"description":"Tudor 2","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29234025","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6BHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 224 |
| Details | Domain: {"description":"Tudor 3","evidences":[{"evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"29234025","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6BHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6BHI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
