7CIM
Crystal structure of L-methionine decarboxylase from Streptomyces sp.590 in complexed with 3-methlythiopropylamine (geminal diamine form).
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue G0F A 601 |
| Chain | Residue |
| A | GLY137 |
| A | HIS393 |
| A | LYS394 |
| A | HOH717 |
| B | TYR421 |
| B | SER432 |
| B | HOH735 |
| A | SER138 |
| A | THR139 |
| A | ASN142 |
| A | HIS195 |
| A | THR283 |
| A | ASP336 |
| A | ALA338 |
| A | SER391 |
| site_id | AC2 |
| Number of Residues | 22 |
| Details | binding site for Di-peptide G0F B 601 and LYS B 394 |
| Chain | Residue |
| A | SER432 |
| A | HOH714 |
| B | GLN64 |
| B | ALA65 |
| B | THR66 |
| B | GLY137 |
| B | SER138 |
| B | THR139 |
| B | ASN142 |
| B | HIS195 |
| B | GLY281 |
| B | THR283 |
| B | ASP336 |
| B | ALA338 |
| B | SER391 |
| B | GLY392 |
| B | HIS393 |
| B | TRP395 |
| B | ALA396 |
| B | GLY397 |
| B | MET532 |
| B | HOH704 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 54 |
| Details | Coiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Site: {"description":"Plays a key role in determining the substrate specificity","evidences":[{"source":"PubMed","id":"33452696","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for enzymatic activity","evidences":[{"source":"PubMed","id":"33452696","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"33452696","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7CIG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7CIM","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
