7CIA

Crystal structure of P.aeruginosa LpxC in complex with inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006796	biological_process	phosphate-containing compound metabolic process
A	0008759	molecular_function	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
A	0009245	biological_process	lipid A biosynthetic process
A	0016787	molecular_function	hydrolase activity
A	0019637	biological_process	organophosphate metabolic process
A	0046872	molecular_function	metal ion binding
A	0103117	molecular_function	UDP-3-O-acyl-N-acetylglucosamine deacetylase activity
A	1901135	biological_process	carbohydrate derivative metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue MPB A 1300

Chain	Residue
A	PHE152
A	PHE176
A	ILE243
A	SER252
A	LEU253
A	HOH1413
A	HOH1483

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site_id	AC2
Number of Residues	7
Details	binding site for residue MPB A 1301

Chain	Residue
A	MET194
A	ILE197
A	ALA214
A	VAL216
A	HOH1531
A	THR190
A	GLY192

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site_id	AC3
Number of Residues	6
Details	binding site for residue ZN A 1302

Chain	Residue
A	HIS78
A	HIS237
A	ASP241
A	HOH1407
A	HOH1542
A	HOH1566

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00388

Chain	Residue	Details
A	HIS264

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site_id	SWS_FT_FI2
Number of Residues	3
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00388

Chain	Residue	Details
A	HIS78
A	HIS237
A	ASP241

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