7CD9
Crystal Structure of SETDB1 tudor domain in complexed with Compound 6
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue FVR A 501 |
| Chain | Residue |
| A | THR212 |
| B | GLN273 |
| B | ASP299 |
| B | FVR501 |
| B | HOH676 |
| A | TYR268 |
| A | TRP275 |
| A | ASP299 |
| A | TYR301 |
| A | GLU386 |
| A | HOH657 |
| A | HOH698 |
| B | ASP270 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue CIT A 502 |
| Chain | Residue |
| A | PHE296 |
| A | PHE297 |
| A | GLY300 |
| A | TYR301 |
| A | ALA302 |
| A | PHE332 |
| A | TYR389 |
| A | SER392 |
| A | HOH601 |
| A | HOH606 |
| A | HOH758 |
| site_id | AC3 |
| Number of Residues | 13 |
| Details | binding site for residue FVR B 501 |
| Chain | Residue |
| A | ASP270 |
| A | GLN273 |
| A | ASP299 |
| A | FVR501 |
| A | HOH682 |
| B | THR212 |
| B | TYR268 |
| B | TRP275 |
| B | ASP299 |
| B | TYR301 |
| B | GLU386 |
| B | HOH650 |
| B | HOH707 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue CIT B 502 |
| Chain | Residue |
| B | PHE296 |
| B | PHE297 |
| B | GLY300 |
| B | TYR301 |
| B | ALA302 |
| B | PHE332 |
| B | TYR389 |
| B | SER392 |
| B | HOH612 |
| B | HOH725 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 126 |
| Details | Domain: {"description":"Tudor 1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 112 |
| Details | Domain: {"description":"Tudor 2"} |
| Chain | Residue | Details |
