7CBG
Crystal structure of threonyl-tRNA synthetase (ThrRS) from Salmonella enterica in complex with an inhibitor
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004829 | molecular_function | threonine-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006435 | biological_process | threonyl-tRNA aminoacylation |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004829 | molecular_function | threonine-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006435 | biological_process | threonyl-tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue FQL A 701 |
| Chain | Residue |
| A | TYR313 |
| A | HIS511 |
| A | ARG512 |
| A | ALA513 |
| A | ZN702 |
| A | HOH921 |
| A | MET317 |
| A | PRO331 |
| A | MET332 |
| A | CYS334 |
| A | ARG363 |
| A | GLN381 |
| A | ASP383 |
| A | HIS385 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 702 |
| Chain | Residue |
| A | CYS334 |
| A | HIS385 |
| A | HIS511 |
| A | FQL701 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue FQL B 701 |
| Chain | Residue |
| B | TYR313 |
| B | ALA316 |
| B | MET317 |
| B | PRO331 |
| B | CYS334 |
| B | ARG363 |
| B | GLN381 |
| B | ASP383 |
| B | HIS385 |
| B | HIS511 |
| B | ARG512 |
| B | ZN702 |
| B | HOH881 |
| B | HOH934 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 702 |
| Chain | Residue |
| B | CYS334 |
| B | HIS385 |
| B | HIS511 |
| B | FQL701 |
