7CB6
The silver-bound 6-phosphogluconate dehydrogenase from Staphylococcus aureus (strain Newman)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0008114 | molecular_function | phosphogluconate 2-dehydrogenase activity |
| A | 0009051 | biological_process | pentose-phosphate shunt, oxidative branch |
| A | 0016054 | biological_process | organic acid catabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019521 | biological_process | D-gluconate metabolic process |
| A | 0046177 | biological_process | D-gluconate catabolic process |
| A | 0050661 | molecular_function | NADP binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0008114 | molecular_function | phosphogluconate 2-dehydrogenase activity |
| B | 0009051 | biological_process | pentose-phosphate shunt, oxidative branch |
| B | 0016054 | biological_process | organic acid catabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019521 | biological_process | D-gluconate metabolic process |
| B | 0046177 | biological_process | D-gluconate catabolic process |
| B | 0050661 | molecular_function | NADP binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| C | 0005829 | cellular_component | cytosol |
| C | 0006098 | biological_process | pentose-phosphate shunt |
| C | 0008114 | molecular_function | phosphogluconate 2-dehydrogenase activity |
| C | 0009051 | biological_process | pentose-phosphate shunt, oxidative branch |
| C | 0016054 | biological_process | organic acid catabolic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019521 | biological_process | D-gluconate metabolic process |
| C | 0046177 | biological_process | D-gluconate catabolic process |
| C | 0050661 | molecular_function | NADP binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| D | 0005829 | cellular_component | cytosol |
| D | 0006098 | biological_process | pentose-phosphate shunt |
| D | 0008114 | molecular_function | phosphogluconate 2-dehydrogenase activity |
| D | 0009051 | biological_process | pentose-phosphate shunt, oxidative branch |
| D | 0016054 | biological_process | organic acid catabolic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019521 | biological_process | D-gluconate metabolic process |
| D | 0046177 | biological_process | D-gluconate catabolic process |
| D | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue AG A 501 |
| Chain | Residue |
| A | MET140 |
| A | HIS185 |
| A | MET357 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue AG A 502 |
| Chain | Residue |
| A | CYS168 |
| A | CYS363 |
| A | AG503 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue AG A 503 |
| Chain | Residue |
| A | CYS168 |
| A | MET357 |
| A | AG502 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue AG A 504 |
| Chain | Residue |
| A | SER138 |
| A | MET357 |
| A | ILE358 |
| A | TRP359 |
| A | CYS363 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue AG A 505 |
| Chain | Residue |
| A | HIS211 |
| A | GLU212 |
| A | PHE238 |
| A | MET239 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue AG B 501 |
| Chain | Residue |
| B | MET140 |
| B | HIS185 |
| B | MET357 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue AG B 502 |
| Chain | Residue |
| B | CYS168 |
| B | CYS363 |
| B | ILE364 |
| B | AG503 |
| B | AG504 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue AG B 503 |
| Chain | Residue |
| B | SER138 |
| B | MET357 |
| B | ILE358 |
| B | TRP359 |
| B | CYS363 |
| B | AG502 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue AG B 504 |
| Chain | Residue |
| B | CYS168 |
| B | MET357 |
| B | AG502 |
| site_id | AD1 |
| Number of Residues | 4 |
| Details | binding site for residue AG B 505 |
| Chain | Residue |
| B | HIS211 |
| B | GLU212 |
| B | PHE238 |
| B | MET239 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue AG C 501 |
| Chain | Residue |
| C | MET140 |
| C | HIS185 |
| C | MET357 |
| site_id | AD3 |
| Number of Residues | 4 |
| Details | binding site for residue AG C 502 |
| Chain | Residue |
| C | CYS168 |
| C | CYS363 |
| C | ILE364 |
| C | AG503 |
| site_id | AD4 |
| Number of Residues | 3 |
| Details | binding site for residue AG C 503 |
| Chain | Residue |
| C | CYS168 |
| C | MET357 |
| C | AG502 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue AG C 504 |
| Chain | Residue |
| C | SER138 |
| C | MET357 |
| C | ILE358 |
| C | TRP359 |
| C | CYS363 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue AG C 505 |
| Chain | Residue |
| C | HIS211 |
| C | GLU212 |
| C | PHE238 |
| C | MET239 |
| site_id | AD7 |
| Number of Residues | 3 |
| Details | binding site for residue AG D 501 |
| Chain | Residue |
| D | MET140 |
| D | HIS185 |
| D | MET357 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue AG D 502 |
| Chain | Residue |
| D | CYS168 |
| D | CYS363 |
| D | ILE364 |
| D | AG503 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue AG D 503 |
| Chain | Residue |
| D | CYS168 |
| D | MET357 |
| D | AG502 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue AG D 504 |
| Chain | Residue |
| D | SER138 |
| D | MET357 |
| D | ILE358 |
| D | TRP359 |
| D | CYS363 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue AG D 505 |
| Chain | Residue |
| D | HIS211 |
| D | PHE238 |
| D | MET239 |
Functional Information from PROSITE/UniProt
| site_id | PS00461 |
| Number of Residues | 13 |
| Details | 6PGD 6-phosphogluconate dehydrogenase signature. IlDtaGQKGTGkW |
| Chain | Residue | Details |
| A | ILE252-TRP264 |
