7CB5
The 6-phosphogluconate dehydrogenase from Staphylococcus aureus (6-phosphogluconate bound)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019521 | biological_process | D-gluconate metabolic process |
| A | 0050661 | molecular_function | NADP binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019521 | biological_process | D-gluconate metabolic process |
| B | 0050661 | molecular_function | NADP binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| C | 0006098 | biological_process | pentose-phosphate shunt |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019521 | biological_process | D-gluconate metabolic process |
| C | 0050661 | molecular_function | NADP binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| D | 0006098 | biological_process | pentose-phosphate shunt |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019521 | biological_process | D-gluconate metabolic process |
| D | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue 6PG A 501 |
| Chain | Residue |
| A | SER127 |
| A | ARG286 |
| A | ILE364 |
| A | HOH608 |
| B | ARG444 |
| B | PHE447 |
| B | HIS450 |
| A | GLY128 |
| A | GLY129 |
| A | LYS182 |
| A | HIS185 |
| A | ASN186 |
| A | TYR190 |
| A | LYS259 |
| A | THR261 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue 6PG B 501 |
| Chain | Residue |
| A | ARG444 |
| A | HIS450 |
| B | ASN101 |
| B | SER127 |
| B | GLY128 |
| B | GLY129 |
| B | LYS182 |
| B | HIS185 |
| B | ASN186 |
| B | GLU189 |
| B | TYR190 |
| B | GLN258 |
| B | LYS259 |
| B | ARG286 |
| B | ILE364 |
| B | HOH609 |
| B | HOH620 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue 6PG C 501 |
| Chain | Residue |
| C | VAL126 |
| C | SER127 |
| C | GLY128 |
| C | LYS182 |
| C | HIS185 |
| C | ASN186 |
| C | GLU189 |
| C | TYR190 |
| C | GLN258 |
| C | LYS259 |
| C | ARG286 |
| C | ILE364 |
| D | ARG444 |
| D | PHE447 |
| D | HIS450 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | binding site for residue 6PG D 501 |
| Chain | Residue |
| C | ARG444 |
| C | HIS450 |
| D | SER127 |
| D | GLY128 |
| D | GLY129 |
| D | LYS182 |
| D | ASN186 |
| D | GLU189 |
| D | TYR190 |
| D | GLY257 |
| D | GLN258 |
| D | LYS259 |
| D | THR261 |
| D | ARG286 |
| D | ILE364 |
Functional Information from PROSITE/UniProt
| site_id | PS00461 |
| Number of Residues | 13 |
| Details | 6PGD 6-phosphogluconate dehydrogenase signature. IlDtaGQKGTGkW |
| Chain | Residue | Details |
| A | ILE252-TRP264 |
