7CB2
The 6-phosphogluconate dehydrogenase (NADP-bound) from Staphylococcus aureus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| A | 0006098 | biological_process | pentose-phosphate shunt |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0019521 | biological_process | D-gluconate metabolic process |
| A | 0050661 | molecular_function | NADP binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| B | 0006098 | biological_process | pentose-phosphate shunt |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0019521 | biological_process | D-gluconate metabolic process |
| B | 0050661 | molecular_function | NADP binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| C | 0006098 | biological_process | pentose-phosphate shunt |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0019521 | biological_process | D-gluconate metabolic process |
| C | 0050661 | molecular_function | NADP binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0004616 | molecular_function | phosphogluconate dehydrogenase (decarboxylating) activity |
| D | 0006098 | biological_process | pentose-phosphate shunt |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0019521 | biological_process | D-gluconate metabolic process |
| D | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue NAP A 501 |
| Chain | Residue |
| A | GLY9 |
| A | ALA11 |
| A | ASN32 |
| A | ARG33 |
| A | SER34 |
| A | LYS37 |
| A | GLN74 |
| A | ALA78 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue NO3 A 502 |
| Chain | Residue |
| A | ASN149 |
| D | ARG340 |
| A | GLU145 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue NO3 A 503 |
| Chain | Residue |
| A | ARG340 |
| D | GLU145 |
| D | ASN149 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue NAP B 501 |
| Chain | Residue |
| B | GLY9 |
| B | ASN32 |
| B | ARG33 |
| B | SER34 |
| B | LYS37 |
| B | GLN74 |
| B | ALA78 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue NO3 B 502 |
| Chain | Residue |
| B | GLU145 |
| B | ASN149 |
| C | ARG340 |
| C | PRO381 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue NAP C 501 |
| Chain | Residue |
| C | ASN32 |
| C | ARG33 |
| C | SER34 |
| C | LYS37 |
| C | VAL73 |
| C | GLN74 |
| C | ALA78 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue CIT C 502 |
| Chain | Residue |
| C | ASN101 |
| C | LYS182 |
| C | ASN186 |
| C | GLU189 |
| C | TYR190 |
| C | MET193 |
| C | GLY260 |
| C | THR261 |
| C | ARG286 |
| D | ARG444 |
| D | HIS450 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | binding site for residue NAP D 501 |
| Chain | Residue |
| D | GLY9 |
| D | LEU10 |
| D | ALA11 |
| D | MET13 |
| D | ASN32 |
| D | ARG33 |
| D | SER34 |
| D | VAL73 |
| D | GLN74 |
| D | ALA78 |
| D | GLY100 |
| D | ASN101 |
| D | VAL126 |
| D | SER127 |
| D | GLY128 |
| D | GLY129 |
| D | CIT502 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | binding site for residue CIT D 502 |
| Chain | Residue |
| C | ARG444 |
| C | PHE447 |
| C | HIS450 |
| D | ASN101 |
| D | GLU189 |
| D | TYR190 |
| D | LYS259 |
| D | THR261 |
| D | ARG286 |
| D | NAP501 |
Functional Information from PROSITE/UniProt
| site_id | PS00461 |
| Number of Residues | 13 |
| Details | 6PGD 6-phosphogluconate dehydrogenase signature. IlDtaGQKGTGkW |
| Chain | Residue | Details |
| A | ILE252-TRP264 |
