7CAV
Versatile cis-prenyltransferase MM_0014 from Methanosarcina mazei (crystal type: co-FG+DMAPP)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002094 | molecular_function | polyprenyltransferase activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0009409 | biological_process | response to cold |
| A | 0009668 | biological_process | plastid membrane organization |
| A | 0016094 | biological_process | polyprenol biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| A | 0033850 | molecular_function | Z-farnesyl diphosphate synthase activity |
| A | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0002094 | molecular_function | polyprenyltransferase activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0009409 | biological_process | response to cold |
| B | 0009668 | biological_process | plastid membrane organization |
| B | 0016094 | biological_process | polyprenol biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0033850 | molecular_function | Z-farnesyl diphosphate synthase activity |
| B | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0002094 | molecular_function | polyprenyltransferase activity |
| C | 0005886 | cellular_component | plasma membrane |
| C | 0009409 | biological_process | response to cold |
| C | 0009668 | biological_process | plastid membrane organization |
| C | 0016094 | biological_process | polyprenol biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| C | 0033850 | molecular_function | Z-farnesyl diphosphate synthase activity |
| C | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0002094 | molecular_function | polyprenyltransferase activity |
| D | 0005886 | cellular_component | plasma membrane |
| D | 0009409 | biological_process | response to cold |
| D | 0009668 | biological_process | plastid membrane organization |
| D | 0016094 | biological_process | polyprenol biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| D | 0033850 | molecular_function | Z-farnesyl diphosphate synthase activity |
| D | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0002094 | molecular_function | polyprenyltransferase activity |
| E | 0005886 | cellular_component | plasma membrane |
| E | 0009409 | biological_process | response to cold |
| E | 0009668 | biological_process | plastid membrane organization |
| E | 0016094 | biological_process | polyprenol biosynthetic process |
| E | 0016740 | molecular_function | transferase activity |
| E | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| E | 0033850 | molecular_function | Z-farnesyl diphosphate synthase activity |
| E | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0002094 | molecular_function | polyprenyltransferase activity |
| F | 0005886 | cellular_component | plasma membrane |
| F | 0009409 | biological_process | response to cold |
| F | 0009668 | biological_process | plastid membrane organization |
| F | 0016094 | biological_process | polyprenol biosynthetic process |
| F | 0016740 | molecular_function | transferase activity |
| F | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| F | 0033850 | molecular_function | Z-farnesyl diphosphate synthase activity |
| F | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
| F | 0046872 | molecular_function | metal ion binding |
| G | 0002094 | molecular_function | polyprenyltransferase activity |
| G | 0005886 | cellular_component | plasma membrane |
| G | 0009409 | biological_process | response to cold |
| G | 0009668 | biological_process | plastid membrane organization |
| G | 0016094 | biological_process | polyprenol biosynthetic process |
| G | 0016740 | molecular_function | transferase activity |
| G | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| G | 0033850 | molecular_function | Z-farnesyl diphosphate synthase activity |
| G | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0002094 | molecular_function | polyprenyltransferase activity |
| H | 0005886 | cellular_component | plasma membrane |
| H | 0009409 | biological_process | response to cold |
| H | 0009668 | biological_process | plastid membrane organization |
| H | 0016094 | biological_process | polyprenol biosynthetic process |
| H | 0016740 | molecular_function | transferase activity |
| H | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| H | 0033850 | molecular_function | Z-farnesyl diphosphate synthase activity |
| H | 0045547 | molecular_function | dehydrodolichyl diphosphate synthase activity |
| H | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue DMA A 301 |
| Chain | Residue |
| A | ASP18 |
| A | MG303 |
| A | HOH413 |
| A | HOH415 |
| A | HOH447 |
| A | HOH465 |
| B | THR216 |
| B | LEU217 |
| B | GLY218 |
| B | HOH404 |
| A | PHE60 |
| A | GLY61 |
| A | ASN66 |
| A | ARG69 |
| A | ARG168 |
| A | ARG174 |
| A | SER176 |
| A | DMA302 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue DMA A 302 |
| Chain | Residue |
| A | PRO17 |
| A | ASP18 |
| A | GLY19 |
| A | ASN20 |
| A | ARG21 |
| A | ARG22 |
| A | TYR35 |
| A | GLY61 |
| A | ASN66 |
| A | ARG69 |
| A | DMA301 |
| A | MG303 |
| A | HOH415 |
| A | HOH432 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 303 |
| Chain | Residue |
| A | ASP18 |
| A | DMA301 |
| A | DMA302 |
| A | HOH413 |
| A | HOH415 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue MG B 301 |
| Chain | Residue |
| B | ASP18 |
| B | DPO303 |
| B | DPO304 |
| B | HOH411 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for residue FQ0 B 302 |
| Chain | Residue |
| B | ASP18 |
| B | ASN20 |
| B | TYR35 |
| B | ILE39 |
| B | GLY42 |
| B | PHE59 |
| B | GLY61 |
| B | ASN66 |
| B | ARG69 |
| B | ALA80 |
| B | SER84 |
| B | DPO303 |
| B | DPO304 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residue DPO B 303 |
| Chain | Residue |
| B | ASP18 |
| B | GLY19 |
| B | ASN20 |
| B | ARG21 |
| B | ARG22 |
| B | TYR35 |
| B | ARG69 |
| B | MG301 |
| B | FQ0302 |
| B | DPO304 |
| B | HOH411 |
| site_id | AC7 |
| Number of Residues | 10 |
| Details | binding site for residue DPO B 304 |
| Chain | Residue |
| B | ASP18 |
| B | ASN66 |
| B | ARG69 |
| B | ARG168 |
| B | ARG174 |
| B | SER176 |
| B | MG301 |
| B | FQ0302 |
| B | DPO303 |
| B | HOH411 |
| site_id | AC8 |
| Number of Residues | 17 |
| Details | binding site for residue DMA C 301 |
| Chain | Residue |
| C | ILE16 |
| C | PRO17 |
| C | ASP18 |
| C | PHE60 |
| C | ASN66 |
| C | ARG168 |
| C | ARG174 |
| C | SER176 |
| C | DMA302 |
| C | MG303 |
| C | HOH404 |
| C | HOH418 |
| C | HOH421 |
| D | TYR185 |
| D | THR216 |
| D | LEU217 |
| D | GLY218 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | binding site for residue DMA C 302 |
| Chain | Residue |
| C | GLY61 |
| C | ASN66 |
| C | ARG69 |
| C | DMA301 |
| C | MG303 |
| C | HOH404 |
| C | HOH421 |
| C | PRO17 |
| C | ASP18 |
| C | GLY19 |
| C | ASN20 |
| C | ARG21 |
| C | ARG22 |
| C | TYR35 |
| site_id | AD1 |
| Number of Residues | 5 |
| Details | binding site for residue MG C 303 |
| Chain | Residue |
| C | ASP18 |
| C | DMA301 |
| C | DMA302 |
| C | HOH404 |
| C | HOH421 |
| site_id | AD2 |
| Number of Residues | 15 |
| Details | binding site for residue DMA D 301 |
| Chain | Residue |
| D | PRO17 |
| D | ASP18 |
| D | GLY19 |
| D | ASN20 |
| D | ARG21 |
| D | ARG22 |
| D | TYR35 |
| D | GLY61 |
| D | ASN66 |
| D | ARG69 |
| D | PHE77 |
| D | DMA302 |
| D | MG303 |
| D | HOH404 |
| D | HOH424 |
| site_id | AD3 |
| Number of Residues | 20 |
| Details | binding site for residue DMA D 302 |
| Chain | Residue |
| C | TYR185 |
| C | THR216 |
| C | LEU217 |
| C | GLY218 |
| C | HOH403 |
| C | HOH437 |
| D | ILE16 |
| D | ASP18 |
| D | PHE60 |
| D | GLY61 |
| D | ASN66 |
| D | ARG69 |
| D | ARG168 |
| D | ARG174 |
| D | SER176 |
| D | DMA301 |
| D | MG303 |
| D | HOH404 |
| D | HOH420 |
| D | HOH424 |
| site_id | AD4 |
| Number of Residues | 5 |
| Details | binding site for residue MG D 303 |
| Chain | Residue |
| D | ASP18 |
| D | DMA301 |
| D | DMA302 |
| D | HOH404 |
| D | HOH424 |
| site_id | AD5 |
| Number of Residues | 18 |
| Details | binding site for residue DMA E 301 |
| Chain | Residue |
| E | ILE16 |
| E | PRO17 |
| E | ASP18 |
| E | PHE60 |
| E | ASN66 |
| E | ARG69 |
| E | ARG168 |
| E | ARG174 |
| E | SER176 |
| E | DMA302 |
| E | MG303 |
| E | HOH403 |
| E | HOH422 |
| E | HOH426 |
| F | TYR185 |
| F | THR216 |
| F | LEU217 |
| F | GLY218 |
| site_id | AD6 |
| Number of Residues | 13 |
| Details | binding site for residue DMA E 302 |
| Chain | Residue |
| E | PRO17 |
| E | ASP18 |
| E | GLY19 |
| E | ASN20 |
| E | ARG21 |
| E | ARG22 |
| E | TYR35 |
| E | GLY61 |
| E | ARG69 |
| E | DMA301 |
| E | MG303 |
| E | HOH403 |
| E | HOH431 |
| site_id | AD7 |
| Number of Residues | 5 |
| Details | binding site for residue MG E 303 |
| Chain | Residue |
| E | ASP18 |
| E | DMA301 |
| E | DMA302 |
| E | HOH403 |
| E | HOH422 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue MG F 301 |
| Chain | Residue |
| F | ASP18 |
| F | DPO303 |
| F | DPO304 |
| F | HOH406 |
| site_id | AD9 |
| Number of Residues | 16 |
| Details | binding site for residue FQ0 F 302 |
| Chain | Residue |
| F | PRO17 |
| F | ASP18 |
| F | ASN20 |
| F | TYR35 |
| F | ILE39 |
| F | GLY42 |
| F | PHE59 |
| F | GLY61 |
| F | ASN66 |
| F | ARG69 |
| F | ALA80 |
| F | SER84 |
| F | PHE128 |
| F | TRP195 |
| F | DPO303 |
| F | HOH432 |
| site_id | AE1 |
| Number of Residues | 11 |
| Details | binding site for residue DPO F 303 |
| Chain | Residue |
| F | ASP18 |
| F | GLY19 |
| F | ASN20 |
| F | ARG21 |
| F | ARG22 |
| F | TYR35 |
| F | ARG69 |
| F | MG301 |
| F | FQ0302 |
| F | DPO304 |
| F | HOH406 |
| site_id | AE2 |
| Number of Residues | 10 |
| Details | binding site for residue DPO F 304 |
| Chain | Residue |
| F | ASP18 |
| F | ARG21 |
| F | ARG69 |
| F | ARG168 |
| F | ARG174 |
| F | SER176 |
| F | MG301 |
| F | DPO303 |
| F | HOH406 |
| F | HOH432 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue MG G 301 |
| Chain | Residue |
| G | ASP18 |
| G | DPO303 |
| G | DPO304 |
| G | HOH410 |
| site_id | AE4 |
| Number of Residues | 13 |
| Details | binding site for residue FQ0 G 302 |
| Chain | Residue |
| G | ASP18 |
| G | ASN20 |
| G | TYR35 |
| G | GLY38 |
| G | ILE39 |
| G | GLY42 |
| G | PHE59 |
| G | GLY61 |
| G | ASN66 |
| G | ARG69 |
| G | PHE77 |
| G | SER84 |
| G | DPO303 |
| site_id | AE5 |
| Number of Residues | 11 |
| Details | binding site for residue DPO G 303 |
| Chain | Residue |
| G | ASP18 |
| G | GLY19 |
| G | ASN20 |
| G | ARG21 |
| G | ARG22 |
| G | TYR35 |
| G | ARG69 |
| G | MG301 |
| G | FQ0302 |
| G | DPO304 |
| G | HOH410 |
| site_id | AE6 |
| Number of Residues | 10 |
| Details | binding site for residue DPO G 304 |
| Chain | Residue |
| A | TYR-1 |
| G | ASP18 |
| G | ARG69 |
| G | ARG168 |
| G | ARG174 |
| G | SER176 |
| G | MG301 |
| G | DPO303 |
| G | HOH408 |
| G | HOH410 |
| site_id | AE7 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 G 305 |
| Chain | Residue |
| G | GLY219 |
| H | ASP18 |
| H | ARG168 |
| H | ARG172 |
| H | SER176 |
| H | MG301 |
| H | DPO303 |
| H | HOH431 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue MG H 301 |
| Chain | Residue |
| G | PO4305 |
| G | HOH418 |
| H | ASP18 |
| H | DPO303 |
| H | HOH431 |
| site_id | AE9 |
| Number of Residues | 14 |
| Details | binding site for residue FQ0 H 302 |
| Chain | Residue |
| H | PRO17 |
| H | ASP18 |
| H | ASN20 |
| H | TYR35 |
| H | GLY38 |
| H | ILE39 |
| H | GLY42 |
| H | PHE59 |
| H | GLY61 |
| H | ASN66 |
| H | ALA80 |
| H | SER84 |
| H | TRP195 |
| H | DPO303 |
| site_id | AF1 |
| Number of Residues | 13 |
| Details | binding site for residue DPO H 303 |
| Chain | Residue |
| G | PO4305 |
| G | HOH418 |
| H | ASP18 |
| H | GLY19 |
| H | ASN20 |
| H | ARG21 |
| H | ARG22 |
| H | TYR35 |
| H | ARG69 |
| H | MG301 |
| H | FQ0302 |
| H | HOH431 |
| H | HOH451 |
